1ECX
 
 | | NIFS-LIKE PROTEIN | | 分子名称: | AMINOTRANSFERASE, CYSTEINE, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Kaiser, J.T, Clausen, T.C, Bourenkow, G.P, Bartunik, H.-D, Steinbacher, S, Huber, R. | | 登録日 | 2000-01-26 | | 公開日 | 2000-03-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J.Mol.Biol., 297, 2000
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5BYZ
 | | ERK5 in complex with small molecule | | 分子名称: | 4-({5-fluoro-4-[2-methyl-1-(propan-2-yl)-1H-imidazol-5-yl]pyrimidin-2-yl}amino)-N-[2-(piperidin-1-yl)ethyl]benzamide, GLYCEROL, Mitogen-activated protein kinase 7 | | 著者 | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | | 登録日 | 2015-06-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
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5BYY
 | | ERK5 IN COMPLEX WITH SMALL MOLECULE | | 分子名称: | 2-{[2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Mitogen-activated protein kinase 7 | | 著者 | Chen, H, Tucker, J, Wang, X, Gavine, P.R, Philips, C, Augustin, M.A, Schreiner, P, Steinbacher, S, Preston, M, Ogg, D. | | 登録日 | 2015-06-11 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Discovery of a novel allosteric inhibitor-binding site in ERK5: comparison with the canonical kinase hinge ATP-binding site.
Acta Crystallogr D Struct Biol, 72, 2016
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1EG5
 | | NIFS-LIKE PROTEIN | | 分子名称: | AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Kaiser, J.T, Clausen, T, Bourenkow, G.P, Bartunik, H.-D, Steinbacher, S, Huber, R. | | 登録日 | 2000-02-13 | | 公開日 | 2000-04-02 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly.
J.Mol.Biol., 297, 2000
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1B9L
 | | 7,8-DIHYDRONEOPTERIN TRIPHOSPHATE EPIMERASE | | 分子名称: | PROTEIN (EPIMERASE) | | 著者 | Ploom, T, Haussmann, C, Hof, P, Steinbacher, S, Bacher, A, Richardson, J, Huber, R. | | 登録日 | 1999-02-11 | | 公開日 | 2000-02-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of 7,8-dihydroneopterin triphosphate epimerase.
Structure Fold.Des., 7, 1999
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1ALL
 | | ALLOPHYCOCYANIN | | 分子名称: | ALLOPHYCOCYANIN, PHYCOCYANOBILIN | | 著者 | Brejc, K, Ficner, R, Huber, R, Steinbacher, S. | | 登録日 | 1995-03-01 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Isolation, crystallization, crystal structure analysis and refinement of allophycocyanin from the cyanobacterium Spirulina platensis at 2.3 A resolution.
J.Mol.Biol., 249, 1995
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1A6E
 | | THERMOSOME-MG-ADP-ALF3 COMPLEX | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | | 著者 | Ditzel, L, Loewe, J, Stock, D, Stetter, K.-O, Huber, H, Huber, R, Steinbacher, S. | | 登録日 | 1998-02-24 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT.
Cell(Cambridge,Mass.), 93, 1998
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1A6D
 | | THERMOSOME FROM T. ACIDOPHILUM | | 分子名称: | THERMOSOME (ALPHA SUBUNIT), THERMOSOME (BETA SUBUNIT) | | 著者 | Ditzel, L, Loewe, J, Stock, D, Stetter, K.-O, Huber, H, Huber, R, Steinbacher, S. | | 登録日 | 1998-02-24 | | 公開日 | 1999-03-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT.
Cell(Cambridge,Mass.), 93, 1998
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5MU8
 | | HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525 | | 分子名称: | Tumor necrosis factor, ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine | | 著者 | Blevitt, J.M, Hack, M.D, Herman, K.L, Jackson, P.F, Krawczuk, P.J, Lebsack, A.D, Liu, A.X, Mirzadegan, T, Nelen, M.I, Patrick, A.P, Steinbacher, S, Milla, M.E, Lumb, K.J. | | 登録日 | 2017-01-12 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-02-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
J. Med. Chem., 60, 2017
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1KZ6
 | | Mutant enzyme W63Y/L119F Lumazine Synthase from S.pombe | | 分子名称: | 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KYY
 | | Lumazine Synthase from S.pombe bound to nitropyrimidinedione | | 分子名称: | 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KZ1
 | | Mutant enzyme W27G Lumazine Synthase from S.pombe | | 分子名称: | 6,7-Dimethyl-8-ribityllumazine Synthase | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KZ9
 | | Mutant Enzyme L119F Lumazine Synthase from S.pombe | | 分子名称: | 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KYX
 | | Lumazine Synthase from S.pombe bound to carboxyethyllumazine | | 分子名称: | 3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID, 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KZ4
 | | Mutant enzyme W63Y Lumazine Synthase from S.pombe | | 分子名称: | 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1KZL
 | | Riboflavin Synthase from S.pombe bound to Carboxyethyllumazine | | 分子名称: | 3-[8-((2S,3S,4R)-2,3,4,5-TETRAHYDROXYPENTYL)-2,4,7-TRIOXO-1,3,8-TRIHYDROPTERIDIN-6-YL]PROPANOIC ACID, MERCURY (II) ION, Riboflavin Synthase | | 著者 | Gerhardt, S, Schott, A.K, Kairies, N, Cushman, M, Illarionov, B, Eisenreich, W, Bacher, A, Huber, R, Steinbacher, S, Fischer, M. | | 登録日 | 2002-02-07 | | 公開日 | 2002-11-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Studies on the Reaction Mechanism of Riboflavin Synthase; X-Ray Crystal Structure of a Complex with 6-Carboxyethyl-7-Oxo-8-Ribityllumazine
STRUCTURE, 10, 2002
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1KYV
 | | Lumazine Synthase from S.pombe bound to riboflavin | | 分子名称: | 6,7-Dimethyl-8-ribityllumazine Synthase, PHOSPHATE ION, RIBOFLAVIN | | 著者 | Gerhardt, S, Haase, I, Steinbacher, S, Kaiser, J.T, Cushman, M, Bacher, A, Huber, R, Fischer, M. | | 登録日 | 2002-02-06 | | 公開日 | 2002-07-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The structural basis of riboflavin binding to Schizosaccharomyces pombe 6,7-dimethyl-8-ribityllumazine synthase.
J.Mol.Biol., 318, 2002
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1TKU
 | | Crystal Structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans in complex with Ribulose-5-phosphate | | 分子名称: | 3,4-Dihydroxy-2-butanone 4-phosphate Synthase, RIBULOSE-5-PHOSPHATE | | 著者 | Echt, S, Bauer, S, Steinbacher, S, Huber, R, Bacher, A, Fischer, M. | | 登録日 | 2004-06-09 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
J.Mol.Biol., 341, 2004
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1TKS
 | | Crystal structure of 3,4-Dihydroxy-2-butanone 4-phosphate Synthase of Candida albicans | | 分子名称: | 3,4-dihydroxy-2-butanone 4-phosphate synthase | | 著者 | Echt, S, Bauer, S, Steinbacher, S, Huber, R, Bacher, A, Fischer, M. | | 登録日 | 2004-06-09 | | 公開日 | 2004-09-07 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Potential anti-infective targets in pathogenic yeasts: structure and properties of 3,4-dihydroxy-2-butanone 4-phosphate synthase of Candida albicans.
J.Mol.Biol., 341, 2004
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1QRC
 | | TAILSPIKE PROTEIN, MUTANT W391A | | 分子名称: | TAILSPIKE PROTEIN | | 著者 | Schuler, B, Furst, F, Osterroth, F, Steinbacher, S, Huber, R, Seckler, R. | | 登録日 | 1999-06-13 | | 公開日 | 2000-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein.
Proteins, 39, 2000
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1QQ1
 | | TAILSPIKE PROTEIN, MUTANT E359G | | 分子名称: | TAILSPIKE PROTEIN | | 著者 | Schuler, B, Furst, F, Osterroth, F, Steinbacher, S, Huber, R, Seckler, R. | | 登録日 | 1999-06-10 | | 公開日 | 2000-04-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Plasticity and steric strain in a parallel beta-helix: rational mutations in the P22 tailspike protein.
Proteins, 39, 2000
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1U7Z
 | | Phosphopantothenoylcysteine synthetase from E. coli, 4'-phosphopantothenoyl-CMP complex | | 分子名称: | Coenzyme A biosynthesis bifunctional protein coaBC, PHOSPHORIC ACID MONO-[3-(3-{[5-(4-AMINO-2-OXO-2H-PYRIMIDIN-1-YL)-3,4- DIHYDROXY-TETRAHYDRO-FURAN-2- YLMETHOXY]-HYDROXY-PHOSPHORYLOXY}-3-OXO-PROPYLCARBAMOYL)-3-HYDROXY-2,2- DIMETHYL-PROPYL] ESTER | | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | | 登録日 | 2004-08-04 | | 公開日 | 2004-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase
STRUCTURE, 12, 2004
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1U7U
 | | Phosphopantothenoylcysteine synthetase from E. coli | | 分子名称: | Coenzyme A biosynthesis bifunctional protein coaBC | | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | | 登録日 | 2004-08-04 | | 公開日 | 2004-11-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase
STRUCTURE, 12, 2004
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1U80
 | | Phosphopantothenoylcysteine synthetase from E. coli, CMP complex | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, Coenzyme A biosynthesis bifunctional protein coaBC, PHOSPHATE ION | | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | | 登録日 | 2004-08-04 | | 公開日 | 2004-11-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase
STRUCTURE, 12, 2004
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1U7W
 | | Phosphopantothenoylcysteine synthetase from E. coli, CTP-complex | | 分子名称: | CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, Coenzyme A biosynthesis bifunctional protein coaBC | | 著者 | Stanitzek, S, Augustin, M.A, Huber, R, Kupke, T, Steinbacher, S. | | 登録日 | 2004-08-04 | | 公開日 | 2004-11-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Basis of CTP-Dependent Peptide Bond Formation in Coenzyme A Biosynthesis Catalyzed by Escherichia coli PPC Synthetase
STRUCTURE, 12, 2004
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