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SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY
分子名称:	AGITOXIN 2
著者	Krezel, A.M, Kasibhatla, C, Hidalgo, P, Mackinnon, R, Wagner, G.
登録日	1995-04-14
公開日	1995-07-10
最終更新日	2017-11-29
実験手法	SOLUTION NMR
主引用文献	Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry. Protein Sci., 4, 1995

1BYW

STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN-ERG POTASSIUM CHANNEL
分子名称:	PROTEIN (HUMAN ERG POTASSIUM CHANNEL)
著者	Cabral, J.H.M, Lee, A, Mackinnon, R.
登録日	1998-10-15
公開日	1998-12-16
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Crystal Structure and Functional Analysis of the Herg Potassium Channel N-Terminus: A Eukaryotic Pas Domain Cell(Cambridge,Mass.), 95, 1998

1BFE

THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95
分子名称:	PSD-95
著者	Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日	1998-05-20
公開日	1998-10-21
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996

1BE9

THE THIRD PDZ DOMAIN FROM THE SYNAPTIC PROTEIN PSD-95 IN COMPLEX WITH A C-TERMINAL PEPTIDE DERIVED FROM CRIPT.
分子名称:	CRIPT, PSD-95
著者	Doyle, D.A, Lee, A, Lewis, J, Kim, E, Sheng, M, Mackinnon, R.
登録日	1998-05-20
公開日	1998-10-21
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (1.82 Å)
主引用文献	Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell(Cambridge,Mass.), 85, 1996

1BL8

POTASSIUM CHANNEL (KCSA) FROM STREPTOMYCES LIVIDANS
分子名称:	POTASSIUM ION, PROTEIN (POTASSIUM CHANNEL PROTEIN)
著者	Doyle, D.A, Cabral, J.M, Pfuetzner, R.A, Kuo, A, Gulbis, J.M, Cohen, S.L, Chait, B.T, Mackinnon, R.
登録日	1998-07-23
公開日	1998-07-29
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	The structure of the potassium channel: molecular basis of K+ conduction and selectivity. Science, 280, 1998

1EXB

STRUCTURE OF THE CYTOPLASMIC BETA SUBUNIT-T1 ASSEMBLY OF VOLTAGE-DEPENDENT K CHANNELS
分子名称:	KV BETA2 PROTEIN, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM CHANNEL KV1.1
著者	Gulbis, J.M, Zhou, M, Mann, S, MacKinnon, R.
登録日	2000-05-02
公開日	2000-07-19
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Structure of the cytoplasmic beta subunit-T1 assembly of voltage-dependent K+ channels. Science, 289, 2000

5U6O

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel
分子名称:	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者	Lee, C.-H, MacKinnon, R.
登録日	2016-12-08
公開日	2017-01-25
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.5 Å)
主引用文献	Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell, 168, 2017

5U6P

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
分子名称:	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11
著者	Lee, C.-H, MacKinnon, R.
登録日	2016-12-08
公開日	2017-01-25
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.51 Å)
主引用文献	Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell, 168, 2017

5U70

Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl
分子名称:	Potassium channel subfamily T member 1
著者	Hite, R.K, MacKinnon, R.
登録日	2016-12-09
公開日	2017-02-08
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.76 Å)
主引用文献	Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel. Cell, 168, 2017

5VA1

Cryo-EM structure of the human ether-a-go-go related K+ channel
分子名称:	Potassium voltage-gated channel subfamily H member 2
著者	Wang, W.W, MacKinnon, R.
登録日	2017-03-24
公開日	2017-05-03
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.7 Å)
主引用文献	Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG. Cell, 169, 2017

5VA3

Cryo-EM structure of the human ether-a-go-go related K+ channel
分子名称:	Potassium voltage-gated channel subfamily H member 2
著者	Wang, W.W, MacKinnon, R.
登録日	2017-03-24
公開日	2017-05-03
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (4 Å)
主引用文献	Cryo-EM Structure of the Open Human Ether-a-go-go-Related K(+) Channel hERG. Cell, 169, 2017

5U76

Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl
分子名称:	Potassium channel subfamily T member 1
著者	Hite, R.K, MacKinnon, R.
登録日	2016-12-11
公開日	2017-02-08
最終更新日	2024-03-13
実験手法	ELECTRON MICROSCOPY (3.76 Å)
主引用文献	Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel. Cell, 168, 2017

5TQQ

Cryo-electron microscopy structure of a bovine CLC-K chloride channel, main (class 1) conformation
分子名称:	Chloride channel protein, Monoclonal antibody, Fab fragment, ...
著者	Park, E, MacKinnon, R.
登録日	2016-10-24
公開日	2017-01-04
最終更新日	2019-11-20
実験手法	ELECTRON MICROSCOPY (3.76 Å)
主引用文献	Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature, 541, 2017

8EP0

Eag Kv channel with voltage sensor in the intermediate conformation
分子名称:	Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者	Mandala, V.S, MacKinnon, R.
登録日	2022-10-04
公開日	2022-11-16
実験手法	ELECTRON MICROSCOPY (4.9 Å)
主引用文献	Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022

8EOW

Eag Kv channel with voltage sensor in the up conformation
分子名称:	Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者	Mandala, V.S, MacKinnon, R.
登録日	2022-10-04
公開日	2022-11-16
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022

8EP1

Eag Kv channel with voltage sensor in the down conformation
分子名称:	Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者	Mandala, V.S, MacKinnon, R.
登録日	2022-10-04
公開日	2022-11-16
実験手法	ELECTRON MICROSCOPY (5.4 Å)
主引用文献	Voltage-sensor movements in the Eag Kv channel under an applied electric field. Proc.Natl.Acad.Sci.USA, 119, 2022

5TR1

Cryo-electron microscopy structure of a bovine CLC-K chloride channel, alternate (class 2) conformation
分子名称:	CHOLESTEROL HEMISUCCINATE, Chloride channel protein, Monoclonal antibody, ...
著者	Park, E, MacKinnon, R.
登録日	2016-10-25
公開日	2017-01-11
最終更新日	2019-11-20
実験手法	ELECTRON MICROSCOPY (3.95 Å)
主引用文献	Structure of a CLC chloride ion channel by cryo-electron microscopy. Nature, 541, 2017

1ORQ

X-ray structure of a voltage-dependent potassium channel in complex with an Fab
分子名称:	6E1 Fab heavy chain, 6E1 Fab light chain, CADMIUM ION, ...
著者	Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
登録日	2003-03-14
公開日	2003-05-06
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	X-ray structure of a voltage-dependent K+ channel Nature, 423, 2003

1K4C

Potassium Channel KcsA-Fab complex in high concentration of K+
分子名称:	DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
著者	Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
登録日	2001-10-07
公開日	2001-11-14
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001

1K4D

Potassium Channel KcsA-Fab complex in low concentration of K+
分子名称:	DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ...
著者	Zhou, Y, Morais-Cabral, J.H, Kaufman, A, MacKinnon, R.
登録日	2001-10-07
公開日	2001-11-14
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Chemistry of ion coordination and hydration revealed by a K+ channel-Fab complex at 2.0 A resolution. Nature, 414, 2001

1ORS

X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab
分子名称:	33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel
著者	Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R.
登録日	2003-03-14
公開日	2003-05-06
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	X-ray structure of a voltage-dependent K+ channel Nature, 423, 2003

1N9P

Crystal Structure of the Cytoplasmic Domain of G-protein Activated Inward Rectifier Potassium Channel 1
分子名称:	G protein-activated inward rectifier potassium channel 1
著者	Nishida, M, MacKinnon, R.
登録日	2002-11-26
公開日	2003-01-07
最終更新日	2017-08-02
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Structural Basis of Inward Rectification: Cytoplasmic Pore of the G Protein-Gated Inward Rectifier GIRK1 at 1.8 A Resolution Cell(Cambridge,Mass.), 111, 2002

1ID1

CRYSTAL STRUCTURE OF THE RCK DOMAIN FROM E.COLI POTASSIUM CHANNEL
分子名称:	PUTATIVE POTASSIUM CHANNEL PROTEIN
著者	Jiang, Y, Pico, A, Cadene, M, Chait, B.T, MacKinnon, R.
登録日	2001-04-02
公開日	2001-04-11
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel. Neuron, 29, 2001

1QRQ

STRUCTURE OF A VOLTAGE-DEPENDENT K+ CHANNEL BETA SUBUNIT
分子名称:	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (KV BETA2 PROTEIN)
著者	Gulbis, J.M, Mann, S, MacKinnon, R.
登録日	1999-06-15
公開日	1999-10-27
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Structure of a voltage-dependent K+ channel beta subunit. Cell(Cambridge,Mass.), 97, 1999

1JVM

KCSA POTASSIUM CHANNEL WITH TBA (TETRABUTYLAMMONIUM) AND RUBIDIUM
分子名称:	RUBIDIUM ION, TETRABUTYLAMMONIUM ION, Voltage-gated potassium channel
著者	Morais-Cabral, J.H, Zhou, Y, MacKinnon, R.
登録日	2001-08-30
公開日	2001-12-05
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Energetic optimization of ion conduction rate by the K+ selectivity filter. Nature, 414, 2001

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