1B9T
 
 | | NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE | | 分子名称: | 1-(4-CARBOXY-2-GUANIDINOPENTYL)-5,5'-DI(HYDROXYMETHYL)PYRROLIDIN-2-ONE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Finley, J.B, Atigadda, V.R, Duarte, F, Zhao, J.J, Brouillette, W.J, Air, G.M, Luo, M. | | 登録日 | 1999-02-15 | | 公開日 | 1999-02-27 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
J.Mol.Biol., 293, 1999
|
|
8FKJ
 | | Yeast ATP Synthase in conformation-3, at pH 6 | | 分子名称: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | | 著者 | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | 登録日 | 2022-12-21 | | 公開日 | 2024-01-24 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8FL8
 | | Yeast ATP Synthase structure in presence of MgATP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | | 著者 | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | 登録日 | 2022-12-21 | | 公開日 | 2024-01-17 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8F39
 | | Yeast ATP synthase in conformation-2, at pH 6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | | 著者 | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | 登録日 | 2022-11-09 | | 公開日 | 2024-02-07 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
|
|
8F29
 | | Yeast ATP synthase in conformation-1 at pH 6 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP synthase protein 8, ATP synthase subunit 4, ... | | 著者 | Sharma, S, Patel, H, Luo, M, Mueller, D.M, Liao, M. | | 登録日 | 2022-11-07 | | 公開日 | 2024-02-07 | | 最終更新日 | 2025-05-28 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Conformational ensemble of yeast ATP synthase at low pH reveals unique intermediates and plasticity in F 1 -F o coupling.
Nat.Struct.Mol.Biol., 31, 2024
|
|
1YIS
 | | Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase | | 分子名称: | SULFATE ION, adenylosuccinate lyase | | 著者 | Symersky, J, Schormann, N, Lu, S, Zhang, Y, Karpova, E, Qiu, S, Huang, W, Cao, Z, Zhou, J, Luo, M, Arabshahi, A, McKinstry, A, Luan, C.-H, Luo, D, Johnson, D, An, J, Tsao, J, Delucas, L, Shang, Q, Gray, R, Li, S, Bray, T, Chen, Y.-J, Southeast Collaboratory for Structural Genomics (SECSG) | | 登録日 | 2005-01-12 | | 公開日 | 2005-01-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
To be Published
|
|
4EIJ
 | |
5EG9
 | | The cap binding site of influenza virus protein PB2 as a drug target | | 分子名称: | Polymerase basic protein 2 | | 著者 | Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M. | | 登録日 | 2015-10-26 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
|
|
5EG7
 | | The cap binding site of influenza virus protein PB2 as a drug target | | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Polymerase basic protein 2 | | 著者 | Severin, C, Rocha de Moura, T, Liu, Y, Li, K, Zheng, X, Luo, M. | | 登録日 | 2015-10-26 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
|
|
5EG8
 | | The cap binding site of influenza virus protein PB2 as a drug target | | 分子名称: | Polymerase basic protein 2, THIOCYANATE ION | | 著者 | Liu, Y, Zheng, X, Severin, C, Rocha de Moura, T, Li, K, Luo, M. | | 登録日 | 2015-10-26 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | The cap-binding site of influenza virus protein PB2 as a drug target.
Acta Crystallogr D Struct Biol, 72, 2016
|
|
8I6O
 | |
8I6R
 | | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Xu, X, Li, J, Luo, M. | | 登録日 | 2023-01-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8I6S
 | | Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Xu, X, Li, J, Luo, M. | | 登録日 | 2023-01-29 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-07-03 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site.
Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
6BJY
 | | VSV Nucleocapsid with Polyamide Bound | | 分子名称: | 4-{[4-(acetylamino)-1-methyl-1H-pyrrole-2-carbonyl]amino}-1-methyl-N-{4-[(1-methyl-1H-pyrrol-3-yl)amino]-4-oxobutyl}-1H-imidazole-2-carboxamide, Nucleoprotein, RNA (45-MER), ... | | 著者 | Gumpper, R.H, Luo, M. | | 登録日 | 2017-11-07 | | 公開日 | 2018-02-28 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | A Polyamide Inhibits Replication of Vesicular Stomatitis Virus by Targeting RNA in the Nucleocapsid.
J. Virol., 92, 2018
|
|
8W6I
 | |
8W6J
 | | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | | 著者 | Li, J, Xu, X, He, Y, Luo, M. | | 登録日 | 2023-08-29 | | 公開日 | 2023-12-20 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of Escherichia coli Str K12 FtsE(E163Q)X/EnvC complex with ATP in peptidisc
To Be Published
|
|
6DVR
 | | Crystal structure of human CARM1 with (R)-SKI-72 | | 分子名称: | (2R,5S)-2-amino-6-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]-5-[(benzylamino)methyl]-N-[2-(4-methoxyphenyl)ethyl]hexanamide (non-preferred name), 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Histone-arginine methyltransferase CARM1, ... | | 著者 | Dong, A, Zeng, H, Hutchinson, A, Seitova, A, Luo, M, Cai, X.C, Ke, W, Wang, J, Shi, C, Zheng, W, Lee, J.P, Ibanez, G, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2018-06-25 | | 公開日 | 2018-07-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystal structure of human CARM1 with (R)-SKI-72
to be published
|
|
8W7A
 | | Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC in the presence of GTP. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Protein kinase domain-containing protein | | 著者 | Li, Y, Luo, M, Shao, K, Li, J. | | 登録日 | 2023-08-30 | | 公開日 | 2024-08-28 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | | 主引用文献 | Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers.
Nat Commun, 15, 2024
|
|
8W7J
 | | Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC with chain A bounded to substrate PneA and GTP. | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, PHOSPHATE ION, PneA LP, ... | | 著者 | Li, Y, Luo, M, Shao, K, Li, J, Li, Z. | | 登録日 | 2023-08-30 | | 公開日 | 2024-08-28 | | 最終更新日 | 2025-06-18 | | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | | 主引用文献 | Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers.
Nat Commun, 15, 2024
|
|
8WGO
 | | Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC in the presence of PneA and GTPrS. | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Li, Y, Luo, M, Shao, K, Li, J. | | 登録日 | 2023-09-22 | | 公開日 | 2024-08-28 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers.
Nat Commun, 15, 2024
|
|
8W7L
 | | Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC mutant H522A. | | 分子名称: | PHOSPHATE ION, PneA, Protein kinase domain-containing protein | | 著者 | Li, Y, Luo, M, Shao, K, Li, J, Li, Z. | | 登録日 | 2023-08-30 | | 公開日 | 2024-09-04 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Structure of PneA bound PneKC at 3.75 Angstroms resolution.
To Be Published
|
|
1IVF
 | |
1IVG
 | |
4Q72
 | | Crystal Structure of Bradyrhizobium japonicum Proline Utilization A (PutA) Mutant D779Y | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Proline dehydrogenase, ... | | 著者 | Tanner, J.J, Pemberton, T.A, Luo, M. | | 登録日 | 2014-04-23 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Kinetic and Structural Characterization of Tunnel-Perturbing Mutants in Bradyrhizobium japonicum Proline Utilization A.
Biochemistry, 53, 2014
|
|
4Q73
 | | Crystal Structure of Bradyrhizobium japonicum Proline Utilization A (PutA) Mutant D778Y | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Proline dehydrogenase, ... | | 著者 | Tanner, J.J, Luo, M, Pemberton, T.A. | | 登録日 | 2014-04-23 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Kinetic and Structural Characterization of Tunnel-Perturbing Mutants in Bradyrhizobium japonicum Proline Utilization A.
Biochemistry, 53, 2014
|
|
