7QQR
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7QQV
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![BU of 7qqv by Molmil](/molmil-images/mine/7qqv) | SpCas9 bound to FANCF off-target3 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target3 non-target strand, FANCF off-target3 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR5
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7QQO
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![BU of 7qqo by Molmil](/molmil-images/mine/7qqo) | |
7QQQ
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7QQU
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![BU of 7qqu by Molmil](/molmil-images/mine/7qqu) | SpCas9 bound to FANCF off-target2 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QQT
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![BU of 7qqt by Molmil](/molmil-images/mine/7qqt) | SpCas9 bound to FANCF off-target1 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR8
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![BU of 7qr8 by Molmil](/molmil-images/mine/7qr8) | |
7QQP
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![BU of 7qqp by Molmil](/molmil-images/mine/7qqp) | |
7QQS
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![BU of 7qqs by Molmil](/molmil-images/mine/7qqs) | SpCas9 bound to FANCF on-target DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QQX
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![BU of 7qqx by Molmil](/molmil-images/mine/7qqx) | SpCas9 bound to FANCF off-target5 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR0
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7QQZ
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![BU of 7qqz by Molmil](/molmil-images/mine/7qqz) | SpCas9 bound to FANCF off-target7 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QQW
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![BU of 7qqw by Molmil](/molmil-images/mine/7qqw) | SpCas9 bound to FANCF off-target4 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR1
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![BU of 7qr1 by Molmil](/molmil-images/mine/7qr1) | |
7QR7
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![BU of 7qr7 by Molmil](/molmil-images/mine/7qr7) | |
7PLH
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![BU of 7plh by Molmil](/molmil-images/mine/7plh) | Scytonema hofmannii TnsC bound to AMPPNP and DNA | 分子名称: | DNA (5'-D(P*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*TP*AP*T)-3'), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Querques, I, Jinek, M. | 登録日 | 2021-08-31 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | Target site selection and remodelling by type V CRISPR-transposon systems. Nature, 599, 2021
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7ZYH
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![BU of 7zyh by Molmil](/molmil-images/mine/7zyh) | Crystal structure of human CPSF30 in complex with hFip1 | 分子名称: | Cleavage and polyadenylation specificity factor subunit 4, Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1, ZINC ION | 著者 | Muckenfuss, L.M, Jinek, M, Migenda Herranz, A.C, Clerici, M. | 登録日 | 2022-05-24 | 公開日 | 2022-09-14 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11, 2022
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7ZO1
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8BD5
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![BU of 8bd5 by Molmil](/molmil-images/mine/8bd5) | Cas12k-sgRNA-dsDNA-S15-TniQ-TnsC transposon recruitment complex | 分子名称: | 30S ribosomal protein S15, ADENOSINE-5'-TRIPHOSPHATE, DNA non-target strand, ... | 著者 | Schmitz, M, Querques, I, Oberli, S, Chanez, C, Jinek, M. | 登録日 | 2022-10-18 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for the assembly of the type V CRISPR-associated transposon complex. Cell, 185, 2022
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8BD4
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![BU of 8bd4 by Molmil](/molmil-images/mine/8bd4) | TniQ-capped Tns-ATP-dsDNA complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*AP*TP*CP*GP*AP*TP*CP*GP*AP*TP*CP*GP*AP*TP*C)-3'), MAGNESIUM ION, ... | 著者 | Querques, I, Schmitz, M, Oberli, S, Chanez, C, Jinek, M. | 登録日 | 2022-10-18 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.44 Å) | 主引用文献 | Structural basis for the assembly of the type V CRISPR-associated transposon complex. Cell, 185, 2022
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8BD6
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![BU of 8bd6 by Molmil](/molmil-images/mine/8bd6) | Cas12k-sgRNA-dsDNA-TnsC non-productive complex. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cas12k, DNA, ... | 著者 | Schmitz, M, Querques, I, Oberli, S, Chanez, C, Jinek, M. | 登録日 | 2022-10-18 | 公開日 | 2022-12-28 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for the assembly of the type V CRISPR-associated transposon complex. Cell, 185, 2022
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7ZY4
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8BQF
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![BU of 8bqf by Molmil](/molmil-images/mine/8bqf) | Adenylate Kinase L107I MUTANT | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | 著者 | Scheerer, D, Adkar, B.V, Bhattacharyya, S, Levy, D, Iljina, M, Iljina, I, Dym, O, Haran, G, Shakhnovich, E.I. | 登録日 | 2022-11-21 | 公開日 | 2023-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase. Proc.Natl.Acad.Sci.USA, 120, 2023
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1GEA
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![BU of 1gea by Molmil](/molmil-images/mine/1gea) | RECEPTOR-BOUND CONFORMATION OF PACAP21 | 分子名称: | PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE | 著者 | Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M. | 登録日 | 2000-10-20 | 公開日 | 2001-04-20 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformation of a peptide ligand bound to its G-protein coupled receptor. Nat.Struct.Biol., 8, 2001
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