1MM7
| Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Quisqualate in a Zinc Crystal Form at 1.65 Angstroms Resolution | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, ZINC ION | 著者 | Jin, R, Horning, M, Mayer, M.L, Gouaux, E. | 登録日 | 2002-09-03 | 公開日 | 2003-02-04 | 最終更新日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mechanism of Activation and Selectivity in a Ligand-Gated Ion Channel: Structural and Functional Studies of GluR2 and Quisqualate Biochemistry, 41, 2003
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1MM6
| crystal structure of the GluR2 ligand binding core (S1S2J) in complex with quisqualate in a non zinc crystal form at 2.15 angstroms resolution | 分子名称: | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, GLUTAMATE RECEPTOR 2, GLYCEROL, ... | 著者 | Jin, R, Horning, M, Mayer, M.L, Gouaux, E. | 登録日 | 2002-09-03 | 公開日 | 2003-02-04 | 最終更新日 | 2017-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Mechanism of activation and selectivity in a ligand-gated ion channel: Structural and functional studies of GluR2 and quisqualate Biochemistry, 41, 2002
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5IXO
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3DXB
| Structure of the UHM domain of Puf60 fused to thioredoxin | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) | 著者 | Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. | 登録日 | 2008-07-24 | 公開日 | 2008-10-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60. J.Biol.Chem., 284, 2009
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2HRA
| Crystal structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA aminoacylation and nuclear export cofactor Arc1p reveal a novel function for an old fold | 分子名称: | Glutamyl-tRNA synthetase, cytoplasmic, IODIDE ION | 著者 | Simader, H, Hothorn, M, Suck, D. | 登録日 | 2006-07-20 | 公開日 | 2006-09-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of the interacting domains from yeast glutamyl-tRNA synthetase and tRNA-aminoacylation and nuclear-export cofactor Arc1p reveal a novel function for an old fold. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2HQT
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2V9K
| Crystal structure of human PUS10, a novel pseudouridine synthase. | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | McCleverty, C.J, Hornsby, M, Spraggon, G, Kreusch, A. | 登録日 | 2007-08-23 | 公開日 | 2007-10-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Pus10, a Novel Pseudouridine Synthase. J.Mol.Biol., 373, 2007
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3E0N
| The X-ray structure of Human Prostasin in complex with DFFR-chloromethyl ketone inhibitor | 分子名称: | DPN-PHE-ARM, GLYCEROL, Prostasin heavy chain, ... | 著者 | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | 登録日 | 2008-07-31 | 公開日 | 2009-06-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci., 18, 2009
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3E1X
| The Crystal Structure of Apo Prostasin at 1.7 Angstroms Resolution | 分子名称: | GLYCEROL, Prostasin | 著者 | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | 登録日 | 2008-08-04 | 公開日 | 2009-05-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci., 18, 2009
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2HHN
| Cathepsin S in complex with non covalent arylaminoethyl amide. | 分子名称: | Cathepsin S, N-[(1R)-1-[(BENZYLSULFONYL)METHYL]-2-{[(1S)-1-METHYL-2-{[4-(TRIFLUOROMETHOXY)PHENYL]AMINO}ETHYL]AMINO}-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE, SULFATE ION | 著者 | Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K. | 登録日 | 2006-06-28 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers Bioorg.Med.Chem.Lett., 16, 2006
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2HH5
| Crystal Structure of Cathepsin S in complex with a Zinc mediated non-covalent arylaminoethyl amide | 分子名称: | CHLORIDE ION, Cathepsin S, N-[(1R)-1-[(BENZYLSULFONYL)METHYL]-2-{[(1S)-1-METHYL-2-{[4-(TRIFLUOROMETHOXY)PHENYL]AMINO}ETHYL]AMINO}-2-OXOETHYL]MORPHOLINE-4-CARBOXAMIDE, ... | 著者 | Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S. | 登録日 | 2006-06-27 | 公開日 | 2006-08-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers. Bioorg.Med.Chem.Lett., 16, 2006
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5LPY
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5IXT
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5IXQ
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5IYV
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5IYX
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3CB6
| Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form B) | 分子名称: | FACT complex subunit spt16 | 著者 | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | 登録日 | 2008-02-21 | 公開日 | 2008-06-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Proc.Natl.Acad.Sci.USA, 105, 2008
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3CB5
| Crystal Structure of the S. pombe Peptidase Homology Domain of FACT complex subunit Spt16 (form A) | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FACT complex subunit spt16 | 著者 | Stuwe, T, Hothorn, M, Lejeune, E, Bortfeld-Miller, M, Scheffzek, K, Ladurner, A.G. | 登録日 | 2008-02-21 | 公開日 | 2008-06-17 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module Proc.Natl.Acad.Sci.USA, 105, 2008
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6GRF
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6XZM
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6XZN
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6XZL
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6GRE
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2PEH
| Crystal structure of the UHM domain of human SPF45 in complex with SF3b155-ULM5 | 分子名称: | Splicing factor 3B subunit 1, Splicing factor 45 | 著者 | Corsini, L, Basquin, J, Hothorn, M, Sattler, M. | 登録日 | 2007-04-03 | 公開日 | 2007-06-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat.Struct.Mol.Biol., 14, 2007
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2PE8
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