1YM3
| Crystal Structure of carbonic anhydrase RV3588c from Mycobacterium tuberculosis | 分子名称: | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), MAGNESIUM ION, ZINC ION | 著者 | Covarrubias, A.S, Larsson, A.M, Hogbom, M, Lindberg, J, Bergfors, T, Bjorkelid, C, Mowbray, S.L, Unge, T, Jones, T.A, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-01-20 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure and function of carbonic anhydrases from Mycobacterium tuberculosis. J.Biol.Chem., 280, 2005
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2A5V
| Crystal structure of M. tuberculosis beta carbonic anhydrase, Rv3588c, tetrameric form | 分子名称: | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), THIOCYANATE ION, ZINC ION | 著者 | Covarrubias, A.S, Bergfors, T, Jones, T.A, Hogbom, M. | 登録日 | 2005-07-01 | 公開日 | 2005-09-20 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Mechanics of the pH-dependent Activity of beta-Carbonic Anhydrase from Mycobacterium tuberculosis J.Biol.Chem., 281, 2006
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1QK0
| CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-IODO-BENZYL ALCOHOL, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), ... | 著者 | Zou, J.-Y, Jones, T.A. | 登録日 | 1999-07-08 | 公開日 | 1999-09-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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1QK2
| WILD TYPE CEL6A WITH A NON-HYDROLYSABLE CELLOTETRAOSE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside, ... | 著者 | Zou, J.-Y, Jones, T.A. | 登録日 | 1999-07-09 | 公開日 | 1999-09-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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1QJW
| CEL6A (Y169F) WITH A NON-HYDROLYSABLE CELLOTETRAOSE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, CELLOBIOHYDROLASE CEL6A (FORMERLY CALLED CBH II), ... | 著者 | Zou, J.-Y, Jones, T.A. | 登録日 | 1999-07-06 | 公開日 | 1999-09-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic Evidence for Substrate Ring Distortion and Protein Conformational Changes During Catalysis in Cellobiohydrolase Cel6A from Trichoderma Reesei Structure, 7, 1999
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2D1F
| Structure of Mycobacterium tuberculosis threonine synthase | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, Threonine synthase | 著者 | Covarrubias, A.S, Bergfors, T, Mannerstedt, K, Oscarson, S, Jones, T.A, Mowbray, S.L, Hogbom, M. | 登録日 | 2005-08-20 | 公開日 | 2006-09-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural, biochemical, and in vivo investigations of the threonine synthase from Mycobacterium tuberculosis. J.Mol.Biol., 381, 2008
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2BOD
| Catalytic domain of endo-1,4-glucanase Cel6A from Thermobifida fusca in complex with methyl cellobiosyl-4-thio-beta-cellobioside | 分子名称: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | 著者 | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | 登録日 | 2005-04-10 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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2BNG
| Structure of an M.tuberculosis LEH-like epoxide hydrolase | 分子名称: | CALCIUM ION, MB2760 | 著者 | Johansson, P, Arand, M, Unge, T, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2005-03-24 | 公開日 | 2005-08-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of an Atypical Epoxide Hydrolase from Mycobacterium Tuberculosis Gives Insights Into its Function. J.Mol.Biol., 351, 2005
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2BOF
| Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca in complex with cellotetrose | 分子名称: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | 登録日 | 2005-04-10 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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2C2I
| Structure and function of Rv0130, a conserved hypothetical protein from M.tuberculosis | 分子名称: | RV0130 | 著者 | Johansson, P, Castell, A, Jones, T.A, Backbro, K. | 登録日 | 2005-09-29 | 公開日 | 2006-09-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Function of Rv0130, a Conserved Hypothetical Protein from Mycobacterium Tuberculosis. Protein Sci., 15, 2006
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2BOG
| Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca in complex with methyl cellobiosyl-4-thio-beta- cellobioside | 分子名称: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-4-thio-beta-D-glucopyranose-(1-4)-methyl beta-D-glucopyranoside | 著者 | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | 登録日 | 2005-04-10 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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2CAB
| STRUCTURE, REFINEMENT AND FUNCTION OF CARBONIC ANHYDRASE ISOZYMES. REFINEMENT OF HUMAN CARBONIC ANHYDRASE I | 分子名称: | CARBONIC ANHYDRASE FORM B, ZINC ION | 著者 | Kannan, K.K, Ramanadham, M, Jones, T.A. | 登録日 | 1983-10-05 | 公開日 | 1984-02-02 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure, refinement, and function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase I Ann.N.Y.Acad.Sci., 429, 1984
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2CHR
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2BOE
| Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca | 分子名称: | ENDOGLUCANASE E-2 | 著者 | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | 登録日 | 2005-04-10 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
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2BI0
| RV0216, A conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdogfold | 分子名称: | CHLORIDE ION, HYPOTHETICAL PROTEIN RV0216 | 著者 | Castell, A, Johansson, P, Unge, T, Jones, T.A, Backbro, K. | 登録日 | 2005-01-20 | 公開日 | 2005-04-25 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rv0216, a Conserved Hypothetical Protein from Mycobacterium Tuberculosis that is Essential for Bacterial Survival During Infection, Has a Double Hotdog Fold Protein Sci., 14, 2005
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2BVC
| Crystal structure of Mycobacterium tuberculosis glutamine synthetase in complex with a transition state mimic | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ... | 著者 | Krajewski, W.W, Jones, T.A, Mowbray, S.L. | 登録日 | 2005-06-23 | 公開日 | 2005-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of Mycobacterium Tuberculosis Glutamine Synthetase in Complex with a Transition-State Mimic Provides Functional Insights. Proc.Natl.Acad.Sci.USA, 102, 2005
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2B43
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4Y6R
| Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, RC137, and manganese | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, CHLORIDE ION, ... | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2015-02-13 | 公開日 | 2015-04-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase. J.Med.Chem., 58, 2015
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4Y6S
| Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, RC134, and manganese | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, MANGANESE (II) ION, ... | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2015-02-13 | 公開日 | 2015-04-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase. J.Med.Chem., 58, 2015
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4Y67
| Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, RC176, and manganese | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, MANGANESE (II) ION, ... | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2015-02-12 | 公開日 | 2015-04-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase. J.Med.Chem., 58, 2015
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4Y6P
| Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, RC177, and manganese | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, CALCIUM ION, ... | 著者 | Sooriyaarachchi, S, Bergfors, T, Jones, T.A, Mowbray, S.L. | 登録日 | 2015-02-13 | 公開日 | 2015-04-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis and Bioactivity of beta-Substituted Fosmidomycin Analogues Targeting 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase. J.Med.Chem., 58, 2015
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1CB2
| CELLOBIOHYDROLASE II, CATALYTIC DOMAIN, MUTANT Y169F | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CELLOBIOHYDROLASE II, alpha-D-mannopyranose | 著者 | Kleywegt, G.J, Szardenings, M, Jones, T.A. | 登録日 | 1995-11-25 | 公開日 | 1996-10-14 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The active site of Trichoderma reesei cellobiohydrolase II: the role of tyrosine 169. Protein Eng., 9, 1996
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1CA2
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4BFY
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4BFT
| Crystal structure of Mycobacterium tuberculosis PanK in complex with a triazole inhibitory compound (1b) and phosphate | 分子名称: | 2-chloro-N-[1-(5-{[2-(4-fluorophenoxy)ethyl]sulfanyl}-4-methyl-4H-1,2,4-triazol-3-yl)ethyl]benzamide, PANTOTHENATE KINASE, PHOSPHATE ION | 著者 | Bjorkelid, C, Bergfors, T, Jones, T.A. | 登録日 | 2013-03-22 | 公開日 | 2013-05-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural and Biochemical Characterization of Compounds Inhibiting Mycobacterium Tuberculosis Pank J.Biol.Chem., 288, 2013
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