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1HIH
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BU of 1hih by Molmil
COMPARATIVE ANALYSIS OF THE X-RAY STRUCTURES OF HIV-1 AND HIV-2 PROTEASES IN COMPLEX WITH CGP 53820, A NOVEL PSEUDOSYMMETRIC INHIBITOR
分子名称: ACETYL-NH-VAL-CYCLOHEXYL-CH2[NCH2CHOH]CH2-BENZYL-VAL-NH-ACETYL, BETA-MERCAPTOETHANOL, HIV-1 PROTEASE
著者Priestle, J.P, Gruetter, M.G.
登録日1995-03-31
公開日1995-07-10
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Comparative analysis of the X-ray structures of HIV-1 and HIV-2 proteases in complex with CGP 53820, a novel pseudosymmetric inhibitor.
Structure, 3, 1995
4J7W
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BU of 4j7w by Molmil
E3_5 DARPin L86A mutant
分子名称: DARPin_E3_5_L86A
著者Seeger, M.A, Gruetter, M.G.
登録日2013-02-14
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
4J8Y
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BU of 4j8y by Molmil
E3_5 DARPin D77S mutant
分子名称: DARPin_E3_5_D77S
著者Seeger, M.A, Gruetter, M.G.
登録日2013-02-15
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
4JB8
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BU of 4jb8 by Molmil
Caspase-7 in Complex with DARPin C7_16
分子名称: Caspase-7 subunit p11, Caspase-7 subunit p20, DARPin C7_16
著者Fluetsch, A, Seeger, M.A, Gruetter, M.G.
登録日2013-02-19
公開日2013-08-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity.
Protein Sci., 22, 2013
4LSZ
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BU of 4lsz by Molmil
Caspase-7 in Complex with DARPin D7.18
分子名称: Caspase-7 subunit p10, Caspase-7 subunit p20, DARPin D7.18
著者Fluetsch, A, Lukarska, M, Gruetter, M.G.
登録日2013-07-23
公開日2014-07-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Combined inhibition of caspase 3 and caspase 7 by two highly selective DARPins slows down cellular demise.
Biochem.J., 461, 2014
3QF4
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BU of 3qf4 by Molmil
Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
分子名称: ABC transporter, ATP-binding protein, MAGNESIUM ION, ...
著者Hohl, M, Briand, C, Gruetter, M.G, Seeger, M.A.
登録日2011-01-21
公開日2012-03-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation
Nat.Struct.Mol.Biol., 19, 2012
1BX8
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BU of 1bx8 by Molmil
HIRUSTASIN FROM HIRUDO MEDICINALIS AT 1.4 ANGSTROMS
分子名称: HIRUSTASIN, SULFATE ION
著者Uson, I, Sheldrick, G.M, De La Fortelle, E, Bricogne, G, Di Marco, S, Priestle, J.P, Gruetter, M.G, Mittl, P.R.E.
登録日1998-10-14
公開日1999-04-27
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.2 A crystal structure of hirustasin reveals the intrinsic flexibility of a family of highly disulphide-bridged inhibitors.
Structure Fold.Des., 7, 1999
2MIB
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BU of 2mib by Molmil
THE STRUCTURE OF MURINE INTERLEUKIN-1 BETA AT 2.8 ANGSTROMS RESOLUTION
分子名称: INTERLEUKIN-1 BETA
著者Priestle, J.P, Van Oostrum, J, Schmitz, A, Gruetter, M.G.
登録日1993-12-06
公開日1994-01-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献The structure of murine interleukin-1 beta at 2.8 A resolution.
J.Struct.Biol., 107, 1991
2P2C
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BU of 2p2c by Molmil
Inhibition of caspase-2 by a designed ankyrin repeat protein (DARPin)
分子名称: Caspase-2
著者Roschitzki Voser, H, Briand, C, Capitani, G, Gruetter, M.G.
登録日2007-03-07
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Inhibition of Caspase-2 by a Designed Ankyrin Repeat Protein: Specificity, Structure, and Inhibition Mechanism.
Structure, 15, 2007
4Q4A
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BU of 4q4a by Molmil
Improved model of AMP-PNP bound TM287/288
分子名称: ABC transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q4J
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BU of 4q4j by Molmil
Structure of crosslinked TM287/288_S498C_S520C mutant
分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q7K
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BU of 4q7k by Molmil
Structure of NBD287 of TM287/288
分子名称: ABC transporter
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
4Q7L
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BU of 4q7l by Molmil
Structure of NBD288 of TM287/288
分子名称: NICKEL (II) ION, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
4Q4H
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BU of 4q4h by Molmil
TM287/288 in its apo state
分子名称: ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-14
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.527 Å)
主引用文献Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Proc.Natl.Acad.Sci.USA, 111, 2014
4Q7M
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BU of 4q7m by Molmil
Structure of NBD288-Avi of TM287/288
分子名称: Uncharacterized ABC transporter ATP-binding protein TM_0288
著者Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A.
登録日2014-04-25
公開日2015-05-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter.
Biochemistry, 54, 2015
3G7Y
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BU of 3g7y by Molmil
Crystal structure of oxidized Ost6L
分子名称: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6
著者Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M.
登録日2009-02-11
公開日2009-06-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.215 Å)
主引用文献Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
3GA4
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BU of 3ga4 by Molmil
Crystal structure of Ost6L (photoreduced form)
分子名称: 1,2-ETHANEDIOL, Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6, TETRAETHYLENE GLYCOL
著者Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M.
登録日2009-02-16
公開日2009-06-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
3G9B
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BU of 3g9b by Molmil
Crystal structure of reduced Ost6L
分子名称: Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit OST6
著者Stirnimann, C.U, Grimshaw, J.P.A, Schulz, B.L, Brozzo, M.S, Fritsch, F, Glockshuber, R, Capitani, G, Gruetter, M.G, Aebi, M.
登録日2009-02-13
公開日2009-06-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Oxidoreductase activity of oligosaccharyltransferase subunits Ost3p and Ost6p defines site-specific glycosylation efficiency.
Proc.Natl.Acad.Sci.USA, 106, 2009
2MJM
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BU of 2mjm by Molmil
The solution NMR structure of the NLRC5 caspase recruitment domain (CARD)
分子名称: Protein NLRC5
著者Gutte, P.G.M, Zerbe, O.
登録日2014-01-12
公開日2014-09-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Unusual structural features revealed by the solution NMR structure of the NLRC5 caspase recruitment domain.
Biochemistry, 53, 2014
2QYJ
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BU of 2qyj by Molmil
Crystal structure of a designed full consensus ankyrin
分子名称: SULFATE ION, ankyrin NI3C
著者Merz, T.
登録日2007-08-15
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Stabilizing ionic interactions in a full-consensus ankyrin repeat protein.
J.Mol.Biol., 376, 2008
1TGJ
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BU of 1tgj by Molmil
HUMAN TRANSFORMING GROWTH FACTOR-BETA 3, CRYSTALLIZED FROM DIOXANE
分子名称: 1,4-DIETHYLENE DIOXIDE, TRANSFORMING GROWTH FACTOR-BETA 3
著者Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
登録日1996-07-09
公開日1997-01-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
1TGK
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BU of 1tgk by Molmil
HUMAN TRANSFORMING GROWTH FACTOR BETA 3, CRYSTALLIZED FROM PEG 4000
分子名称: TRANSFORMING GROWTH FACTOR BETA 3
著者Mittl, P.R.E, Priestle, J.P, Gruetter, M.G.
登録日1996-07-10
公開日1997-03-12
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding.
Protein Sci., 5, 1996
3NOG
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BU of 3nog by Molmil
Designed ankyrin repeat protein (DARPin) Binders to AcrB: Plasticity of the Interface
分子名称: Acriflavine resistance protein B, Designed ankyrin repeat protein
著者Monroe, N, Briand, C, Gruetter, M.G.
登録日2010-06-25
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface
J.Struct.Biol., 174, 2011
3NOC
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BU of 3noc by Molmil
Designed ankyrin repeat protein (DARPin) binders to AcrB: Plasticity of the Interface
分子名称: Acriflavine resistance protein B, Designed ankyrin repeat protein
著者Monroe, N, Briand, C, Gruetter, M.G.
登録日2010-06-25
公開日2011-05-18
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Designed ankyrin repeat protein binders for the crystallization of AcrB: Plasticity of the dominant interface
J.Struct.Biol., 174, 2011
3N5I
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BU of 3n5i by Molmil
Crystal structure of the precursor (S250A mutant) of the N-terminal beta-aminopeptidase BapA
分子名称: Beta-peptidyl aminopeptidase, GLYCEROL, SULFATE ION
著者Merz, T, Heck, T, Geueke, B, Kohler, H.-P, Gruetter, M.G.
登録日2010-05-25
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Autoproteolytic and catalytic mechanisms for the beta-aminopeptidase BapA--a member of the Ntn hydrolase family.
Structure, 20, 2012

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