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3UI6
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BU of 3ui6 by Molmil
0.89 A resolution crystal structure of human Parvulin 14 in complex with oxidized DTT
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4, SODIUM ION, ...
著者Mueller, J.W, Link, N.M, Matena, A, Hoppstock, L, Rueppel, A, Bayer, P, Blankenfeldt, W.
登録日2011-11-04
公開日2012-11-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献0.89 A resolution crystal structure of human Parvulin 14 in complex with oxidized DTT
To be Published
5K1S
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BU of 5k1s by Molmil
crystal structure of AibC
分子名称: Oxidoreductase, zinc-binding dehydrogenase family, ZINC ION
著者Bock, T, Mueller, R, Blankenfeldt, W.
登録日2016-05-18
公開日2016-08-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of AibC, a reductase involved in alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Acta Crystallogr.,Sect.F, 72, 2016
5K7F
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BU of 5k7f by Molmil
Crystal structure of apo AibR
分子名称: ACETATE ION, Transcriptional regulator, TetR family
著者Bock, T, Volz, C, Mueller, R, Blankenfeldt, W.
登録日2016-05-26
公開日2016-12-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
5K7Z
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BU of 5k7z by Molmil
Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA
分子名称: DNA (32-MER), Isovaleryl-coenzyme A, Transcriptional regulator, ...
著者Bock, T, Volz, C, Mueller, R, Blankenfeldt, W.
登録日2016-05-27
公開日2016-12-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Crystal structure of AibR in complex with isovaleryl coenzyme A and operator DNA
to be published
5K7H
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BU of 5k7h by Molmil
Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A
分子名称: CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ...
著者Bock, T, Volz, C, Mueller, R, Blankenfeldt, W.
登録日2016-05-26
公開日2016-12-21
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
3ZHH
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BU of 3zhh by Molmil
X-ray structure of the full-length beta-lactamase from M.tuberculosis
分子名称: BETA-LACTAMASE, SULFATE ION
著者Feiler, C, Fisher, A.C, Marrichi, M.J, Wright, L, Schmidpeter, P.A.M, Blankenfeldt, W, Pavelka, M, DeLisa, M.P.
登録日2012-12-21
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Directed Evolution of Mycobacterium Tuberculosis Beta-Lactamase Reveals Gatekeeper Residue that Regulates Antibiotic Resistance and Catalytic Efficiency.
Plos One, 8, 2013
3N6O
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BU of 3n6o by Molmil
Crystal structure of the GEF and P4M domain of DrrA/SidM from Legionella pneumophila
分子名称: SULFATE ION, guanine nucleotide exchange factor
著者Schoebel, S, Blankenfeldt, W, Goody, R.S, Itzen, A.
登録日2010-05-26
公開日2010-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献High-affinity binding of phosphatidylinositol 4-phosphate by Legionella pneumophila DrrA.
Embo Rep., 11, 2010
3NKU
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BU of 3nku by Molmil
Crystal structure of the N-terminal domain of DrrA/SidM from Legionella pneumophila
分子名称: DI(HYDROXYETHYL)ETHER, DrrA, TRIETHYLENE GLYCOL
著者Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A.
登録日2010-06-21
公開日2010-08-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science, 329, 2010
3NKV
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BU of 3nkv by Molmil
Crystal structure of Rab1b covalently modified with AMP at Y77
分子名称: ADENOSINE MONOPHOSPHATE, BARIUM ION, MAGNESIUM ION, ...
著者Mueller, M.P, Peters, H, Blankenfeldt, W, Goody, R.S, Itzen, A.
登録日2010-06-21
公開日2010-08-04
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b.
Science, 329, 2010
7AL5
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BU of 7al5 by Molmil
Crystal structure of the selenomethionine substituted hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Feiler, C.G, Blankenfeldt, W.
登録日2020-10-05
公開日2020-11-11
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Crystal structure of the selenomethionine substituted hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
To Be Published
7AL6
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BU of 7al6 by Molmil
Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Probable hydrolase, ...
著者Feiler, C.G, Blankenfeldt, W.
登録日2020-10-05
公開日2020-10-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1
To Be Published
5OE5
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BU of 5oe5 by Molmil
Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 3)
分子名称: 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate--CoA ligase, DI(HYDROXYETHYL)ETHER
著者Witzgall, F, Ewert, W, Blankenfeldt, W.
登録日2017-07-07
公開日2017-09-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis.
Chembiochem, 18, 2017
5OE6
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BU of 5oe6 by Molmil
Crystal structure of the N-terminal domain of PqsA in complex with 6-fluoroanthraniloyl-AMP (crystal form 1)
分子名称: 6-fluoroanthraniloyl-AMP, Anthranilate--CoA ligase, TRIETHYLENE GLYCOL
著者Witzgall, F, Ewert, W, Blankenfeldt, W.
登録日2017-07-07
公開日2017-09-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis.
Chembiochem, 18, 2017
5OE3
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BU of 5oe3 by Molmil
Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 1)
分子名称: 1,2-ETHANEDIOL, 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, ACETATE ION, ...
著者Witzgall, F, Ewert, W, Blankenfeldt, W.
登録日2017-07-07
公開日2017-09-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis.
Chembiochem, 18, 2017
5OE4
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BU of 5oe4 by Molmil
Crystal structure of the N-terminal domain of PqsA in complex with anthraniloyl-AMP (crystal form 2)
分子名称: 5'-O-[(S)-[(2-aminobenzoyl)oxy](hydroxy)phosphoryl]adenosine, Anthranilate--CoA ligase
著者Witzgall, F, Ewert, W, Blankenfeldt, W.
登録日2017-07-07
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.904 Å)
主引用文献Structures of the N-Terminal Domain of PqsA in Complex with Anthraniloyl- and 6-Fluoroanthraniloyl-AMP: Substrate Activation in Pseudomonas Quinolone Signal (PQS) Biosynthesis.
Chembiochem, 18, 2017
6YA1
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BU of 6ya1 by Molmil
Zinc metalloprotease ProA
分子名称: ACETATE ION, CALCIUM ION, ZINC ION, ...
著者Schmelz, S, Blankenfeldt, W.
登録日2020-03-11
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
7NBW
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BU of 7nbw by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist
分子名称: Transcriptional regulator MvfR, ~{N}-[3-(4-fluorophenyl)prop-2-ynyl]-2-(trifluoromethyl)pyridin-4-amine
著者Schmelz, S, Blankenfeldt, W.
登録日2021-01-28
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.
Eur.J.Med.Chem., 226, 2021
6YIZ
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BU of 6yiz by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with triazolo-pyridine inverse agonist A
分子名称: 7-oxidanylidene-8-[2-(4-sulfonaphthalen-1-yl)hydrazinyl]-8~{H}-naphthalene-1,3-disulfonic acid, MAGNESIUM ION, Transcriptional regulator MvfR, ...
著者Schmelz, S, Blankenfeldt, W.
登録日2020-04-01
公開日2021-04-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.163 Å)
主引用文献A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Adv Sci, 8, 2021
6YZE
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BU of 6yze by Molmil
Zinc metalloprotease ProA from native source
分子名称: ZINC ION, Zinc metalloproteinase
著者Schmelz, S, Blankenfeldt, W.
登録日2020-05-06
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Zinc metalloprotease ProA of Legionella pneumophila increases alveolar septal thickness in human lung tissue explants by collagen IV degradation.
Cell.Microbiol., 23, 2021
6ZDT
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BU of 6zdt by Molmil
Crystal structure of eukaryotic Fibrillarin with Nop56 N-terminal domain
分子名称: Nucleolar protein 56, rRNA 2'-O-methyltransferase fibrillarin
著者Hoefler, S, Lukat, P, Carlomagno, T, Blankenfeldt, W.
登録日2020-06-15
公開日2021-02-03
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献High-resolution structure of eukaryotic Fibrillarin interacting with Nop56 amino-terminal domain.
Rna, 27, 2021
7OC5
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BU of 7oc5 by Molmil
Alpha-humulene synthase AsR6 from Sarocladium schorii
分子名称: Alpha-humulene synthase AsR6, MAGNESIUM ION, ZINC ION
著者Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J.
登録日2021-04-26
公開日2021-07-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OC6
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BU of 7oc6 by Molmil
Selenomethionine derivative of alpha-humulene synthase AsR6 from Sarocladium schorii
分子名称: Alpha-humulene synthase asR6, GLYCEROL, SULFATE ION, ...
著者Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J.
登録日2021-04-26
公開日2021-07-07
最終更新日2021-09-15
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
7OC4
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BU of 7oc4 by Molmil
Alpha-humulene synthase AsR6 from Sarocladium schorii in complex with thiolodiphosphate and a cyclized reaction product.
分子名称: (1E,4E,8E)-2,6,6,9-Tetramethyl-1,4-8-cycloundecatriene, (R,R)-2,3-BUTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Schotte, C, Lukat, P, Deuschmann, A, Blankenfeldt, W, Cox, R.J.
登録日2021-04-26
公開日2021-07-07
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Understanding and Engineering the Stereoselectivity of Humulene Synthase.
Angew.Chem.Int.Ed.Engl., 60, 2021
7ZPN
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BU of 7zpn by Molmil
Crystal Structure of IscR from Dinoroseobacter shibae
分子名称: GLYCEROL, HTH-type transcriptional regulator, SULFATE ION
著者Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E.
登録日2022-04-28
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
8AJQ
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BU of 8ajq by Molmil
Crystal structure of PA2722 from Pseudomonas aeruginosa PAO1
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CENP-V/GFA domain-containing protein, GLYCEROL, ...
著者Popp, M.A, Blankenfeldt, W.
登録日2022-07-28
公開日2022-10-05
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of PA2722 from P. aeruginosa PAO1
To Be Published

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件を2024-06-12に公開中

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