8G9X
 
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Changela, A, Gorman, J, Kwong, P.D. | | 登録日 | 2023-02-22 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
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1C9S
 | | CRYSTAL STRUCTURE OF A COMPLEX OF TRP RNA-BINDING ATTENUATION PROTEIN WITH A 53-BASE SINGLE STRANDED RNA CONTAINING ELEVEN GAG TRIPLETS SEPARATED BY AU DINUCLEOTIDES | | 分子名称: | SINGLE STRANDED RNA (55-MER), TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN | | 著者 | Antson, A.A, Dodson, E.J, Dodson, G.G, Greaves, R.B, Chen, X.-P, Gollnick, P. | | 登録日 | 1999-08-03 | | 公開日 | 1999-09-15 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA.
Nature, 401, 1999
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7YAA
 | | Crystal structure analysis of cp3 bound BCLxl | | 分子名称: | Bcl-2-like protein 1, GLYCEROL, N-(2-acetamidoethyl)-4-(4-methanoyl-1,3-thiazol-2-yl)benzamide, ... | | 著者 | Li, F.W, Liu, C, Wu, C.L, Wu, D.L. | | 登録日 | 2022-06-27 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
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7Y90
 | | Crystal Structure Analysis of cp1 bound BCL2 | | 分子名称: | (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, Apoptosis regulator Bcl-2, cp1 peptide | | 著者 | Li, F.W. | | 登録日 | 2022-06-24 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
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7Y8D
 | | Crystal structure of cp1 bound BCLxl | | 分子名称: | (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, Bcl-2-like protein 1, cp1 peptide | | 著者 | Li, F.W, Liu, C, Wu, C.L, Wu, D.L. | | 登録日 | 2022-06-23 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
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7YA5
 | | Crystal structure analysis of cp1 bound BCL2/G101V | | 分子名称: | (2R)-3-[2-(aminomethyl)-3-azanyl-1-[4-[2-(2-chloranylethanoylamino)ethylcarbamoyl]phenyl]prop-1-enyl]sulfanyl-2-(carboxyamino)propanoic acid, Apoptosis regulator Bcl-2, cp1 peptide | | 著者 | Li, F.W, Liu, C, Wu, C.L, Wu, D.L. | | 登録日 | 2022-06-27 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
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7YB7
 | | anti-apoptotic protein BCL-2-M12 | | 分子名称: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1, N-(2-acetamidoethyl)-4-(4,5-dihydro-1,3-thiazol-2-yl)benzamide, cp2 peptide | | 著者 | Li, F.W, Liu, C, Wu, D.L. | | 登録日 | 2022-06-29 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cyclic peptides discriminate BCL-2 and its clinical mutants from BCL-X L by engaging a single-residue discrepancy.
Nat Commun, 15, 2024
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8ABV
 | | Crystal structure of SpLdpA in complex with erythro-DGPD | | 分子名称: | (1R,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, GLYCEROL, ... | | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.683 Å) | | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABT
 | | Crystal structure of NaLdpA in complex with the product analog Resveratrol | | 分子名称: | RESVERATROL, SULFATE ION, SnoaL-like domain-containing protein | | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABU
 | | Crystal structure of NaLdpA mutant H97Q in complex with erythro-DGPD | | 分子名称: | (1S,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SnoaL-like domain-containing protein | | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.661 Å) | | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8ABW
 | | Crystal structure of SpLdpA in complex with threo-DGPD | | 分子名称: | (1R,2R)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, (1S,2S)-1,2-bis(3-methoxy-4-oxidanyl-phenyl)propane-1,3-diol, SULFATE ION, ... | | 著者 | Zahn, M, Kuatsjah, E, Beckham, G.T, McGeehan, J.E. | | 登録日 | 2022-07-04 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5HD0
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5HDU
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5HDX
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5HE4
 | | BACE-1 in complex with (4aR,7aS)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-3-methyl-4-oxooctahydro-2H-pyrrolo[3,4-d]pyrimidin-2-iminium | | 分子名称: | (2E,4aR,7aS)-7a-(2,6-difluorophenyl)-6-(5-fluoro-4-methoxy-6-methylpyrimidin-2-yl)-2-imino-3-methyloctahydro-4H-pyrrolo[3,4-d]pyrimidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID | | 著者 | Orth, P. | | 登録日 | 2016-01-05 | | 公開日 | 2016-03-16 | | 最終更新日 | 2016-04-27 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structure-Based Design of an Iminoheterocyclic beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central A beta in Nonhuman Primates.
J.Med.Chem., 59, 2016
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6KRG
 | | Crystal structure of sfGFP Y182TMSiPhe | | 分子名称: | CHLORIDE ION, GLYCEROL, Green fluorescent protein, ... | | 著者 | Sun, J.P, Wang, J.Y, Zhu, Z.L, He, Q.T, Xiao, P. | | 登録日 | 2019-08-21 | | 公開日 | 2020-09-09 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1 H-NMR probe.
Nat Commun, 11, 2020
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7AL0
 | | Crystal Structure of Heymonin, a Novel Frog-derived Peptide | | 分子名称: | CHLORIDE ION, Heymonin | | 著者 | Kascakova, B, Prudnikova, T, Kuta Smatanova, I, Xu, X. | | 登録日 | 2020-10-03 | | 公開日 | 2021-04-21 | | 最終更新日 | 2021-05-05 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Characterization and functional analysis of cathelicidin-MH, a novel frog-derived peptide with anti-septicemic properties.
Elife, 10, 2021
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8EBU
 | | XPC release from Core7-XPA-DNA (Cy5) | | 分子名称: | DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, DNA1, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBS
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8EBT
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8EBY
 | | XPC release from Core7-XPA-DNA (AP) | | 分子名称: | DNA, DNA repair protein complementing XP-A cells, DNA repair protein complementing XP-C cells, ... | | 著者 | Kim, J, Yang, W. | | 登録日 | 2022-08-31 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Lesion recognition by XPC, TFIIH and XPA in DNA excision repair.
Nature, 617, 2023
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8EBV
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8EBW
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8EBX
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7YGI
 | | Crystal structure of p53 DBD domain in complex with azurin | | 分子名称: | Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ... | | 著者 | Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q. | | 登録日 | 2022-07-11 | | 公開日 | 2023-02-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination.
Commun Biol, 6, 2023
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