5XRH
 
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5XRN
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5Y03
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5XRL
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5YT4
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5XRJ
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5XRG
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5XRK
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8U7I
 | | Structure of the phage immune evasion protein Gad1 bound to the Gabija GajAB complex | | 分子名称: | Endonuclease GajA, Gabija Anti-Defense 1, Gabija protein GajB | | 著者 | Antine, S.P, Johnson, A.G, Mooney, S.E, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2023-09-15 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structural basis of Gabija anti-phage defence and viral immune evasion.
Nature, 625, 2024
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7O4D
 | | QR2 inhibitor from a novel sulfanamide series to tackle age related oxidative stress and cognitive decline | | 分子名称: | 8-methyl-2-(4-methyl-3-piperazin-1-ylsulfonyl-phenyl)imidazo[1,2-a]pyridine, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... | | 著者 | Gould, N.L, Scherer, G.R, Carvalh, S, Shurrush, K, Edry, E, Elkobi, A, David, O, Dym, O, Albeck, S, Peleg, Y, Germain, N, Babaev, I, Sharir, H, Lefker, B, Subramanyam, C, Barr, H, Rosenblum, K. | | 登録日 | 2021-04-06 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.249 Å) | | 主引用文献 | Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer's disease phenotype in mice.
J.Clin.Invest., 133, 2023
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8OIK
 | | D-PHAT domain (NTD) of human SAMD4A | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Protein Smaug homolog 1 | | 著者 | Kubikova, J, Jeske, M. | | 登録日 | 2023-03-23 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Structural basis for binding of Drosophila Smaug to the GPCR Smoothened and to the germline inducer Oskar.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8SM3
 | | Structure of Bacillus cereus VD045 Gabija GajA-GajB Complex | | 分子名称: | Endonuclease GajA, Gabija protein GajB, SULFATE ION | | 著者 | Antine, S.P, Mooney, S.E, Johnson, A.G, Kranzusch, P.J. | | 登録日 | 2023-04-25 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of Gabija anti-phage defence and viral immune evasion.
Nature, 625, 2024
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8TTO
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7N51
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7N50
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7N52
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6UW1
 | | The crystal structure of FbiA from Mycobacterium Smegmatis, Fo bound form | | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, Phosphoenolpyruvate transferase | | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | | 登録日 | 2019-11-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
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6UW7
 | | The crystal structure of FbiA from Mycobacterium smegmatis, Dehydro-F420-0 bound form | | 分子名称: | 2-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[2,4,8-tris(oxidanylidene)-1,9-dihydropyrimido[4,5-b]quinolin-10-yl]pentoxy]phosphoryl]oxyprop-2-enoic acid, CALCIUM ION, GLYCEROL, ... | | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Izore, T, Greening, C. | | 登録日 | 2019-11-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.342 Å) | | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
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6UW3
 | | The crystal structure of FbiA from Mycobacterium Smegmatis, GDP Bound form | | 分子名称: | CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | | 登録日 | 2019-11-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
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6UVX
 | | The crystal structure of FbiA from Mycobacterium Smegmatis, Apo state | | 分子名称: | CALCIUM ION, Phosphoenolpyruvate transferase | | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | | 登録日 | 2019-11-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
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6UW5
 | | The crystal structure of FbiA from Mycobacterium smegmatis, GDP and Fo bound form | | 分子名称: | 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. | | 登録日 | 2019-11-04 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
mSystems, 5, 2020
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8FNW
 | | Structure of RdrA-RdrB complex from Escherichia coli RADAR defense system | | 分子名称: | Adenosine deaminase, Archaeal ATPase, ZINC ION | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (6.73 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNT
 | | Structure of RdrA from Escherichia coli RADAR defense system | | 分子名称: | Archaeal ATPase | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNV
 | | Structure of RdrB from Escherichia coli RADAR defense system | | 分子名称: | Adenosine deaminase, ZINC ION | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.11 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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8FNU
 | | Structure of RdrA from Streptococcus suis RADAR defense system | | 分子名称: | KAP NTPase domain-containing protein | | 著者 | Duncan-Lowey, B, Johnson, A.G, Rawson, S, Mayer, M.L, Kranzusch, P.J. | | 登録日 | 2022-12-28 | | 公開日 | 2023-02-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.
Cell, 186, 2023
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