6VGN
 
 | | ClpP1P2 complex from M. tuberculosis bound to ADEP | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, R0M-WFP-ALO-PRO-YCP-ALA-MP8 | | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | | 登録日 | 2020-01-08 | | 公開日 | 2020-03-18 | | 最終更新日 | 2020-04-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
5GAR
 | | Thermus thermophilus V/A-ATPase, conformation 1 | | 分子名称: | Archaeal/vacuolar-type H+-ATPase subunit I, V-type ATP synthase alpha chain, V-type ATP synthase beta chain, ... | | 著者 | Schep, D.G, Zhao, J, Rubinstein, J.L. | | 登録日 | 2016-02-05 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | | 主引用文献 | Models for the a subunits of the Thermus thermophilus V/A-ATPase and Saccharomyces cerevisiae V-ATPase enzymes by cryo-EM and evolutionary covariance.
Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
8SMR
 | |
8SNH
 | |
8SQL
 | |
8SQ0
 | | Cleaved Ycf1p Dimer in the IFwide-beta conformation | | 分子名称: | (1R)-2-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(pentadecanoyloxy)methyl]ethyl (12E)-hexadeca-9,12-dienoate, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Metal resistance protein YCF1, ... | | 著者 | Bickers, S.C, Benlekbir, S, Rubinstein, J.L, Kanelis, V. | | 登録日 | 2023-05-04 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of a dimeric ABC transporter
To Be Published
|
|
8SQM
 | |
7MPE
 | |
7LKF
 | | WT Chicken Scap L1-L7 / Fab 4G10 complex focused refinement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4G10 heavy chain, 4G10 light chain, ... | | 著者 | Kober, D.L, Radhakrishnan, A, Goldstein, J.L, Brown, M.S, Clark, L.D, Bai, X.-C, Rosenbaum, D.M. | | 登録日 | 2021-02-02 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing.
Cell, 184, 2021
|
|
7LKH
 | | Chicken Scap D435V L1-L7 domain / Fab complex focused map | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4G10 Fab heavy chain, 4G10 Fab kappa chain, ... | | 著者 | Kober, D.L, Radhakrishnan, A, Goldstein, J.L, Brown, M.S, Clark, L.D, Bai, X.-C, Rosenbaum, D.M. | | 登録日 | 2021-02-02 | | 公開日 | 2021-06-30 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing.
Cell, 184, 2021
|
|
7MD2
 | | The F1 region of ammocidin-bound Saccharomyces cerevisiae ATP synthase | | 分子名称: | (3~{E},5~{Z},7~{E},9~{R},10~{S},11~{E},13~{E},15~{E},17~{R},18~{S},20~{S})-20-[(1~{R})-1-[(2~{S},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},4~{S},5~{S},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-4-oxidanyl-oxan-2-yl]oxy-3-methoxy-6-(3-methoxypropyl)-5-methyl-2,4-bis(oxidanyl)oxan-2-yl]ethyl]-5,18-dimethoxy-3,7,9,11,13,15-hexamethyl-10-[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13,15-hexaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | | 著者 | Guo, H, Rubinstein, J.L. | | 登録日 | 2021-04-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
|
|
7MD3
 | | The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase | | 分子名称: | (3~{E},5~{E},7~{E},9~{R},10~{R},11~{E},13~{E},17~{S},18~{S},20~{S})-18-methoxy-20-[(~{R})-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(2~{R})-3-methoxy-2-[(2~{R},4~{S},5~{S},6~{S})-5-[(2~{S},4~{R},5~{R},6~{R})-4-methoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4,6-dimethyl-4-oxidanyl-oxan-2-yl]oxy-propyl]-3,5-dimethyl-2,4-bis(oxidanyl)oxan-2-yl]-oxidanyl-methyl]-10-[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-methoxy-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-3,5,7,9,13-pentamethyl-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... | | 著者 | Guo, H, Rubinstein, J.L. | | 登録日 | 2021-04-03 | | 公開日 | 2021-08-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia
Biorxiv, 2021
|
|
5I1M
 | |
6HWH
 | | Structure of a functional obligate respiratory supercomplex from Mycobacterium smegmatis | | 分子名称: | CARDIOLIPIN, COPPER (II) ION, Co-purified unknown peptide built as polyALA, ... | | 著者 | Wiseman, B, Nitharwal, R.G, Fedotovskaya, O, Schafer, J, Guo, H, Kuang, Q, Benlekbir, S, Sjostrand, D, Adelroth, P, Rubinstein, J.L, Brzezinski, P, Hogbom, M. | | 登録日 | 2018-10-12 | | 公開日 | 2018-11-07 | | 最終更新日 | 2019-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structure of a functional obligate complex III2IV2respiratory supercomplex from Mycobacterium smegmatis.
Nat. Struct. Mol. Biol., 25, 2018
|
|
6B8H
 | | Mosaic model of yeast mitochondrial ATP synthase monomer | | 分子名称: | AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ... | | 著者 | Guo, H, Bueler, S.A, Rubinstein, J.L. | | 登録日 | 2017-10-07 | | 公開日 | 2018-01-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Atomic model for the dimeric FO region of mitochondrial ATP synthase.
Science, 358, 2017
|
|
6B2Z
 | |
6BTM
 | | Structure of Alternative Complex III from Flavobacterium johnsoniae (Wild Type) | | 分子名称: | (2S)-3-hydroxypropane-1,2-diyl ditetradecanoate, Alternative Complex III subunit A, Alternative Complex III subunit B, ... | | 著者 | Sun, C, Benlekbir, S, Venkatakrishnan, P, Yuhang, W, Tajkhorshid, E, Rubinstein, J.L, Gennis, R.B. | | 登録日 | 2017-12-07 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of the alternative complex III in a supercomplex with cytochrome oxidase.
Nature, 557, 2018
|
|
2P3F
 | | Crystal structure of the factor Xa/NAP5 complex | | 分子名称: | Anti-coagulant protein 5, Coagulation factor X, SODIUM ION | | 著者 | Rios-Steiner, J.L, Murakami, M.T, Tulinsky, A, Arni, R.K. | | 登録日 | 2007-03-08 | | 公開日 | 2007-11-06 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Active and exo-site inhibition of human factor Xa: structure of des-Gla factor Xa inhibited by NAP5, a potent nematode anticoagulant protein from Ancylostoma caninum
J.Mol.Biol., 371, 2007
|
|
7RH6
 | | Mycobacterial CIII2CIV2 supercomplex, inhibitor free, -Lpqe cyt cc open | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
|
|
7RH7
 | | Mycobacterial CIII2CIV2 supercomplex, Telacebec (Q203) bound | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
|
|
7RH5
 | | Mycobacterial CIII2CIV2 supercomplex, Inhibitor free | | 分子名称: | (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-(palmitoyloxy)propyl (E)-octadec-9-enoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... | | 著者 | Di Trani, J.M, Yanofsky, D.J, Rubinstein, J.L. | | 登録日 | 2021-07-16 | | 公開日 | 2021-08-04 | | 最終更新日 | 2021-11-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structure of mycobacterial CIII 2 CIV 2 respiratory supercomplex bound to the tuberculosis drug candidate telacebec (Q203).
Elife, 10, 2021
|
|
7RJA
 | |
7RJE
 | | Complex III2 from Candida albicans, Inz-5 bound | | 分子名称: | 3-[2-fluoro-5-(trifluoromethyl)phenyl]-7-methyl-1-[(2-methyl-2H-tetrazol-5-yl)methyl]-1H-indazole, Cytochrome b, Cytochrome b-c1 complex subunit 2, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
|
|
7RJD
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in c position | | 分子名称: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
|
|
7RJC
 | | Complex III2 from Candida albicans, inhibitor free, Rieske head domain in intermediate position | | 分子名称: | Cytochrome b, Cytochrome b-c1 complex subunit 2, mitochondrial, ... | | 著者 | Di Trani, J.M, Rubinstein, J.L. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-15 | | 最終更新日 | 2022-01-19 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III.
Structure, 30, 2022
|
|
