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6IF7
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BU of 6if7 by Molmil
Crystal Structure of AA10 Lytic Polysaccharide Monooxygenase from Tectaria macrodonta
分子名称: COPPER (II) ION, Chitin binding protein, GLYCEROL, ...
著者Archana, A, Yadav, S.K, Singh, P.K, Vasudev, P.G.
登録日2018-09-18
公開日2019-04-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insecticidal fern protein Tma12 is possibly a lytic polysaccharide monooxygenase.
Planta, 249, 2019
6KML
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BU of 6kml by Molmil
2.09 Angstrom resolution crystal structure of tetrameric HigBA toxin-antitoxin complex from E.coli
分子名称: Antitoxin HigA, mRNA interferase toxin HigB
著者Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M.
登録日2019-07-31
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.095 Å)
主引用文献2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
6KMQ
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BU of 6kmq by Molmil
2.3 Angstrom resolution structure of dimeric HigBA toxin-antitoxin complex from E. coli
分子名称: Antitoxin HigA, mRNA interferase toxin HigB
著者Jadhav, P, Sinha, V.K, Rothweiler, U, Singh, M.
登録日2019-07-31
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献2.09 angstrom Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.
Biochem.J., 477, 2020
7M05
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BU of 7m05 by Molmil
CryoEM structure of PRMT5 bound to covalent PBM-site inhibitor BRD-6988
分子名称: 2-(5-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-{[2-(pyridin-2-yl)ethyl]sulfamoyl}phenyl)acetamide, Methylosome protein 50, Protein arginine N-methyltransferase 5
著者McMillan, B.J, McKinney, D.C, Timm, D.E.
登録日2021-03-10
公開日2021-03-17
最終更新日2021-08-25
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Discovery of a First-in-Class Inhibitor of the PRMT5-Substrate Adaptor Interaction.
J.Med.Chem., 64, 2021
5Z47
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BU of 5z47 by Molmil
Crystal structure of pyrrolidone carboxylate peptidase I with disordered loop A from Deinococcus radiodurans R1
分子名称: DIMETHYL SULFOXIDE, Pyrrolidone-carboxylate peptidase
著者Agrawal, R, Kumar, A, Kumar, A, Makde, R.D.
登録日2018-01-10
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of pyrrolidone-carboxylate peptidase I from Deinococcus radiodurans reveal the mechanism of L-pyroglutamate recognition.
Acta Crystallogr D Struct Biol, 75, 2019
5ZAU
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BU of 5zau by Molmil
Complex of the human FYN SH3 and monobody binder
分子名称: Monobody Binder, Tyrosine-protein kinase Fyn
著者Reddy, P.P, Gulyani, A, Das, R.
登録日2018-02-09
公開日2019-09-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献A Fyn biosensor reveals pulsatile, spatially localized kinase activity and signaling crosstalk in live mammalian cells.
Elife, 9, 2020
5Z48
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BU of 5z48 by Molmil
Crystal structure of pyrrolidone carboxylate peptidase I from Deinococcus radiodurans R1 bound to pyroglutamate
分子名称: DIMETHYL SULFOXIDE, PYROGLUTAMIC ACID, Pyrrolidone-carboxylate peptidase, ...
著者Agrawal, R, Kumar, A, Kumar, A, Makde, R.D.
登録日2018-01-10
公開日2019-01-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Crystal structures of pyrrolidone-carboxylate peptidase I from Deinococcus radiodurans reveal the mechanism of L-pyroglutamate recognition.
Acta Crystallogr D Struct Biol, 75, 2019
5L02
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BU of 5l02 by Molmil
S324T variant of B. pseudomallei KatG
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, PHOSPHATE ION, ...
著者Loewen, P.C.
登録日2016-07-26
公開日2016-08-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural characterization of the Ser324Thr variant of the catalase-peroxidase (KatG) from Burkholderia pseudomallei
J. Mol. Biol., 345, 2005
6IFF
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BU of 6iff by Molmil
Crystal structure of M1 zinc metallopeptidase E323A mutant from Deinococcus radiodurans
分子名称: SODIUM ION, TYROSINE, ZINC ION, ...
著者Agrawal, R, Kumar, A, Kumar, A, Gaur, N.K, Makde, R.D.
登録日2018-09-20
公開日2019-09-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
6KP1
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BU of 6kp1 by Molmil
Crystal structure of two domain M1 zinc metallopeptidase E323A mutant bound to L-methionine amino acid
分子名称: METHIONINE, SODIUM ION, ZINC ION, ...
著者Agrawal, R, Kumar, A, Kumar, A, Makde, R.D.
登録日2019-08-13
公開日2020-06-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
6KP0
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BU of 6kp0 by Molmil
Crystal structure of two domain M1 zinc metallopeptidase E323A mutant bound to L-arginine
分子名称: ARGININE, SODIUM ION, ZINC ION, ...
著者Agrawal, R, Kumar, A, Kumar, A, Makde, R.D.
登録日2019-08-13
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
6KOZ
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BU of 6koz by Molmil
Crystal structure of two domain M1 zinc metallopeptidase E323 mutant bound to L-Leucine amino acid
分子名称: LEUCINE, SODIUM ION, ZINC ION, ...
著者Agrawal, R, Kumar, A, Kumar, A, Makde, R.D.
登録日2019-08-13
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for the unusual substrate specificity of unique two-domain M1 metallopeptidase.
Int.J.Biol.Macromol., 147, 2020
6URI
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BU of 6uri by Molmil
HIV-1 Nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex
分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Jia, X, Kwon, Y.
登録日2019-10-23
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of CD4 downregulation by HIV-1 Nef.
Nat.Struct.Mol.Biol., 27, 2020
5QTZ
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BU of 5qtz by Molmil
TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 6-[1-(2,2-DIFLUOROETHYL)-4-(6-METHYLPYRIDIN-2-YL)-1H-IMIDAZOL-5-YL]IMIDAZO[1,2-A]PYRIDINE
分子名称: 6-[1-(2,2-difluoroethyl)-4-(6-methylpyridin-2-yl)-1H-imidazol-5-yl]imidazo[1,2-a]pyridine, GLYCEROL, TGF-beta receptor type-1
著者Sheriff, S.
登録日2019-11-19
公開日2020-02-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGF beta R1 Inhibitor as an Immuno-oncology Agent.
Acs Med.Chem.Lett., 11, 2020
5QU0
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BU of 5qu0 by Molmil
TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 6-[4-(3-CHLORO-4-FLUOROPHENYL)-1-(2-HYDROXYETHYL)-1H-IMIDAZOL-5-YL]IMIDAZO[1,2-B]PYRIDAZINE-3-CARBONITRILE
分子名称: 6-[4-(3-chloro-4-fluorophenyl)-1-(2-hydroxyethyl)-1H-imidazol-5-yl]imidazo[1,2-b]pyridazine-3-carbonitrile, GLYCEROL, TGF-beta receptor type-1
著者Sheriff, S.
登録日2019-11-19
公開日2020-02-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGF beta R1 Inhibitor as an Immuno-oncology Agent.
Acs Med.Chem.Lett., 11, 2020
5SW5
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BU of 5sw5 by Molmil
Crystal structure of native catalase-peroxidase KatG at pH7.5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-08
公開日2016-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.
EMBO Rep., 6, 2005
5SX3
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BU of 5sx3 by Molmil
Crystal structure of the catalase-peroxidase KatG of B. pseudomaallei at pH 4.5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-09
公開日2016-08-31
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes.
Biochemistry, 45, 2006
5SW6
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BU of 5sw6 by Molmil
Crystal structure of an oxoferryl species of catalase-peroxidase KatG at pH5.6
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, OXYGEN ATOM, ...
著者Loewen, P.C.
登録日2016-08-08
公開日2016-08-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.
EMBO Rep., 6, 2005
5SX0
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BU of 5sx0 by Molmil
Crystal structure of an oxoferryl species of catalase-peroxidase KatG at pH7.5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-09
公開日2016-08-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.
EMBO Rep., 6, 2005
5SX7
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BU of 5sx7 by Molmil
Crystal structure of catalase-peroxidase KatG of B. pseudomallei at pH 8.5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-09
公開日2016-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes.
Biochemistry, 45, 2006
5SX6
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BU of 5sx6 by Molmil
Crystal structure of the catalase-peroxidase KatG of B. pseudomallei at pH 6.5
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-09
公開日2016-08-31
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Roles for Arg426 and Trp111 in the modulation of NADH oxidase activity of the catalase-peroxidase KatG from Burkholderia pseudomallei inferred from pH-induced structural changes.
Biochemistry, 45, 2006
5SW4
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BU of 5sw4 by Molmil
Crystal structure of native catalase-peroxidase KatG at pH8.0
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Catalase-peroxidase, ...
著者Loewen, P.C.
登録日2016-08-08
公開日2016-08-24
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A molecular switch and electronic circuit modulate catalase activity in catalase-peroxidases.
EMBO Rep., 6, 2005
8AVA
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BU of 8ava by Molmil
Leukotriene A4 hydrolase in complex with 4-(4-benzylphenyl)-oxazol-2-amine
分子名称: 4-[4-(phenylmethyl)phenyl]-1,3-oxazol-2-amine, ACETATE ION, GLYCEROL, ...
著者Teder, T, Haeggstrom, J.Z.
登録日2022-08-26
公開日2023-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.354 Å)
主引用文献Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase.
Int J Mol Sci, 24, 2023
8AWH
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BU of 8awh by Molmil
Leukotriene A4 hydrolase in complex with 4-(4-Benzylphenyl)-selenazol-2-amine
分子名称: 4-[4-(phenylmethyl)phenyl]-1,3-selenazol-2-amine, ACETATE ION, GLYCEROL, ...
著者Teder, T, Haeggstrom, J.Z.
登録日2022-08-29
公開日2023-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Modulation of the 5-Lipoxygenase Pathway by Chalcogen-Containing Inhibitors of Leukotriene A 4 Hydrolase.
Int J Mol Sci, 24, 2023
5A7Z
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BU of 5a7z by Molmil
Crystal structure of Sulfolobus acidocaldarius Trm10 at 2.1 angstrom resolution.
分子名称: TRNA (ADENINE(9)-N1)-METHYLTRANSFERASE
著者Van Laer, B, Roovers, M, Wauters, L, Kasprzak, J, Dyzma, M, Deyaert, E, Feller, A, Bujnicki, J, Droogmans, L, Versees, W.
登録日2015-07-10
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and Functional Insights Into tRNA Binding and Adenosine N1-Methylation by an Archaeal Trm10 Homologue.
Nucleic Acids Res., 44, 2016

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