4BKM
 
 | | Crystal structure of the murine AUM (phosphoglycolate phosphatase) capping domain as a fusion protein with the catalytic core domain of murine chronophin (pyridoxal phosphate phosphatase) | | 分子名称: | MAGNESIUM ION, NITRATE ION, PYRIDOXAL PHOSPHATE PHOSPHATASE, ... | | 著者 | Knobloch, G, Seifried, A, Gohla, A, Schindelin, H. | | 登録日 | 2013-04-26 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Evolutionary and Structural Analyses of the Mammalian Haloacid Dehalogenase-Type Phosphatases Aum and Chronophin Provide Insight Into the Basis of Their Different Substrate Specificities.
J.Biol.Chem., 289, 2014
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4BX2
 | | Crystal Structure of murine Chronophin (Pyridoxal Phosphate Phosphatase) in complex with Beryllium trifluoride | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | | 著者 | Knobloch, G, Gohla, A, Schindelin, H. | | 登録日 | 2013-07-08 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.193 Å) | | 主引用文献 | Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop.
J.Biol.Chem., 289, 2014
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6FGC
 | | Crystal structure of Gephyrin E domain in complex with Artesunate | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | | 著者 | Kasaragod, V.B, Schindelin, H. | | 登録日 | 2018-01-10 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101, 2019
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4BX3
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4BX0
 | | Crystal Structure of a Monomeric Variant of murine Chronophin (Pyridoxal Phosphate phosphatase) | | 分子名称: | GLYCEROL, MAGNESIUM ION, PYRIDOXAL PHOSPHATE PHOSPHATASE | | 著者 | Kestler, C, Knobloch, G, Gohla, A, Schindelin, H. | | 登録日 | 2013-07-08 | | 公開日 | 2013-12-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Chronophin Dimerization is Required for Proper Positioning of its Substrate Specificity Loop
J.Biol.Chem., 289, 2014
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7PYV
 | | Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10 | | 分子名称: | UBD, Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-like modifier-activating enzyme 1,Ubiquitin-like modifier-activating enzyme 6 | | 著者 | Li, S, Truongvan, N, Schindelin, H. | | 登録日 | 2021-10-11 | | 公開日 | 2022-08-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.27 Å) | | 主引用文献 | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
Nat Commun, 13, 2022
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7PVN
 | | Crystal Structure of Human UBA6 in Complex with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Truongvan, N, Li, S, Schindelin, H. | | 登録日 | 2021-10-05 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10.
Nat Commun, 13, 2022
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7PUX
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7POE
 | | Phosphoglycolate Phosphatase with Inhibitor CP1 | | 分子名称: | 2-[[4-[4-[(2-carboxyphenyl)carbamoyl]phenoxy]phenyl]carbonylamino]benzoic acid, GLYCEROL, Glycerol-3-phosphate phosphatase, ... | | 著者 | Schloetzer, J, Fratz, S, Schindelin, H. | | 登録日 | 2021-09-08 | | 公開日 | 2022-12-21 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (3.16 Å) | | 主引用文献 | Glycolytic flux control by drugging phosphoglycolate phosphatase.
Nat Commun, 13, 2022
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6GXY
 | | Tryparedoxin from Trypanosoma brucei in complex with CFT | | 分子名称: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, Tryparedoxin | | 著者 | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | | 登録日 | 2018-06-27 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes.
Angew. Chem. Int. Ed. Engl., 58, 2019
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6GXG
 | | Tryparedoxin from Trypanosoma brucei in complex with CFT | | 分子名称: | 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one, GLYCEROL, Tryparedoxin | | 著者 | Bader, N, Wagner, A, Hellmich, U, Schindelin, H. | | 登録日 | 2018-06-27 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes.
Angew. Chem. Int. Ed. Engl., 58, 2019
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6FGD
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6HSO
 | | Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), ACETATE ION, ... | | 著者 | Kasaragod, V.B, Schindelin, H. | | 登録日 | 2018-10-01 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins.
Neuron, 101, 2019
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4TK4
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4TK2
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4TK1
 | | Geph E in complex with a GABA receptor alpha3 subunit derived peptide in space group P21212 | | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, Gamma-aminobutyric acid receptor subunit alpha-3, ... | | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | | 登録日 | 2014-05-25 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin.
Nat Commun, 5, 2014
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4TK3
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1JW9
 | | Structure of the Native MoeB-MoaD Protein Complex | | 分子名称: | MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 1, ... | | 著者 | Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H. | | 登録日 | 2001-09-03 | | 公開日 | 2001-11-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.
Nature, 414, 2001
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1JLJ
 | | 1.6 Angstrom crystal structure of the human neuroreceptor anchoring and molybdenum cofactor biosynthesis protein gephyrin | | 分子名称: | FORMIC ACID, SODIUM ION, gephyrin | | 著者 | Schwarz, G, Schrader, N, Mendel, R.R, Hecht, H.-J, Schindelin, H. | | 登録日 | 2001-07-16 | | 公開日 | 2001-09-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications.
J.Mol.Biol., 312, 2001
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4U90
 | | GephE in complex with PEG crosslinked GABA receptor alpha3 subunit derived dimeric peptide | | 分子名称: | 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), 1,4-BUTANEDIOL, Gamma-aminobutyric acid receptor subunit alpha-3, ... | | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | | 登録日 | 2014-08-05 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors.
Angew.Chem.Int.Ed.Engl., 54, 2015
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4U91
 | | GephE in complex with Para-Phenyl crosslinked Glycine receptor beta subunit derived dimeric peptide | | 分子名称: | 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | | 登録日 | 2014-08-05 | | 公開日 | 2014-12-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors.
Angew.Chem.Int.Ed.Engl., 54, 2015
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1JWA
 | | Structure of the ATP-bound MoeB-MoaD Protein Complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, ... | | 著者 | Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H. | | 登録日 | 2001-09-03 | | 公開日 | 2001-11-21 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.
Nature, 414, 2001
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1JWB
 | | Structure of the Covalent Acyl-Adenylate Form of the MoeB-MoaD Protein Complex | | 分子名称: | ADENOSINE MONOPHOSPHATE, MOLYBDOPTERIN BIOSYNTHESIS MOEB PROTEIN, MOLYBDOPTERIN [MPT] CONVERTING FACTOR, ... | | 著者 | Lake, M.W, Wuebbens, M.M, Rajagopalan, K.V, Schindelin, H. | | 登録日 | 2001-09-03 | | 公開日 | 2001-11-21 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Mechanism of ubiquitin activation revealed by the structure of a bacterial MoeB-MoaD complex.
Nature, 414, 2001
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4PD1
 | | Structure of gephyrin E domain with Glycine-beta receptor peptide | | 分子名称: | ACETATE ION, GLYCEROL, Gephyrin, ... | | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | | 登録日 | 2014-04-17 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | | 主引用文献 | Modulation of gephyrin-glycine receptor affinity by multivalency.
Acs Chem.Biol., 9, 2014
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6HRS
 | | Structure of the TRPML2 ELD at pH 4.5 | | 分子名称: | GLYCEROL, Mucolipin-2 | | 著者 | Bader, N, Viet, K.K, Wagner, A, Hellmich, U.A, Schindelin, H. | | 登録日 | 2018-09-28 | | 公開日 | 2019-06-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure of the Human TRPML2 Ion Channel Extracytosolic/Lumenal Domain.
Structure, 27, 2019
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