5U4W
| Cryo-EM Structure of Immature Zika Virus | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, E protein, M protein, ... | 著者 | Mangala Prasad, V, Miller, A.S, Klose, T, Sirohi, D, Buda, G, Jiang, W, Kuhn, R.J, Rossmann, M.G. | 登録日 | 2016-12-06 | 公開日 | 2017-01-11 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | 主引用文献 | Structure of the immature Zika virus at 9 angstrom resolution. Nat. Struct. Mol. Biol., 24, 2017
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7K56
| Structure of VCP dodecamer purified from H1299 cells | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K59
| Structure of apo VCP hexamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K57
| Structure of apo VCP dodecamer generated from bacterially recombinant VCP/p97 | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Yu, G, Bai, Y, Li, K, Jiang, W, Zhang, Z.Y. | 登録日 | 2020-09-16 | 公開日 | 2021-10-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Cryo-electron microscopy structures of VCP/p97 reveal a new mechanism of oligomerization regulation. Iscience, 24, 2021
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7K5W
| Cryo-EM structure of heterologous protein complex loaded Thermotoga maritima encapsulin capsid | 分子名称: | Maritimacin | 著者 | Xiong, X, Sun, C, Vago, F.S, Klose, T, Zhu, J, Jiang, W. | 登録日 | 2020-09-17 | 公開日 | 2020-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Cryo-EM Structure of Heterologous Protein Complex Loaded Thermotoga Maritima Encapsulin Capsid. Biomolecules, 10, 2020
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7KEI
| DQA1*01:02/DQB1*06:02 in complex with a hemagglutinin peptide from the H1N1 pandemic flu virus. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA peptide from 2009 H1N1 pandemic flu virus., ... | 著者 | Birtley, J.R, Stern, L.J, Mellins, E.D, Jiang, W. | 登録日 | 2020-10-10 | 公開日 | 2021-10-13 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a flu peptide. To Be Published
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7KH1
| Baseplate Complex for Myoviridae Phage XM1 | 分子名称: | baseplate organization protein, gp11, baseplate stabilizing protein, ... | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | 登録日 | 2020-10-19 | 公開日 | 2021-10-27 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine Biorxiv, 2021
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7KLN
| Myoviridae Phage XM1 Neck Region (12-fold) | 分子名称: | Head completion protein, gp1, Portal protein | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | 登録日 | 2020-10-30 | 公開日 | 2021-11-03 | 最終更新日 | 2022-05-25 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine Biorxiv, 2021
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7KJK
| The Neck region of Phage XM1 (6-fold symmetry) | 分子名称: | Collar spike protein, Head completion protein, Tail sheath protein, ... | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | 登録日 | 2020-10-26 | 公開日 | 2021-11-03 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine Biorxiv, 2021
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7KMX
| The capsid of Myoviridae Phage XM1 | 分子名称: | Major capsid protein, Minor capsid protein | 著者 | Wang, Z, Klose, T, Jiang, W, Kuhn, R.J. | 登録日 | 2020-11-03 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of Vibrio phage XM1, a simple contractile DNA injection machine Biorxiv, 2021
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7TMC
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7UN5
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7UMQ
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6H1X
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6H2L
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6H1Q
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8WY7
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 22 | 分子名称: | 2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]-~{N}-(4-oxidanylcyclohexyl)ethanamide, Bromodomain-containing protein 4 | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WY3
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 21 | 分子名称: | Bromodomain-containing protein 4, ~{N}-cyclopropyl-2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]ethanamide | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WYG
| Crystal Structure of the second bromodomain of human BRD2 in complex with the inhibitor 22 | 分子名称: | 2-[[5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-2-oxidanylidene-pyridin-4-yl]amino]-~{N}-(4-oxidanylcyclohexyl)ethanamide, Bromodomain-containing protein 2 | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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8WXY
| Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor 23 | 分子名称: | 5-[2-(4-fluoranyl-2,6-dimethyl-phenoxy)-5-(2-oxidanylpropan-2-yl)phenyl]-1-methyl-4-[(2-morpholin-4-yl-2-oxidanylidene-ethyl)amino]pyridin-2-one, Bromodomain-containing protein 4, GLYCEROL | 著者 | Xu, H, Zhao, X, Shen, H, Xu, Y, Wu, X. | 登録日 | 2023-10-30 | 公開日 | 2024-01-24 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | Discovery of Novel Phenoxyaryl Pyridones as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with High Selectivity for the Second Bromodomain (BD2) to Potentially Treat Acute Myeloid Leukemia. J.Med.Chem., 67, 2024
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5XBO
| Lanthanoid tagging via an unnatural amino acid for protein structure characterization | 分子名称: | Polyubiquitin-B, TERBIUM(III) ION, UV excision repair protein RAD23 homolog A | 著者 | Jiang, W, Gu, X, Dong, X, Tang, C. | 登録日 | 2017-03-21 | 公開日 | 2017-05-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Lanthanoid tagging via an unnatural amino acid for protein structure characterization J. Biomol. NMR, 67, 2017
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7DPM
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-12-20 | 公開日 | 2021-02-17 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | 主引用文献 | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV. Mabs, 13, 2021
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6EAZ
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4WUM
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4WJA
| Crystal Structure of PAXX | 分子名称: | Uncharacterized protein C9orf142 | 著者 | Xing, M, Yang, M, Huo, W, Feng, F, Wei, L, Ning, S, Yan, Z, Li, W, Wang, Q, Hou, M, Dong, C, Guo, R, Gao, G, Ji, J, Lan, L, Liang, H, Xu, D. | 登録日 | 2014-09-29 | 公開日 | 2015-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway. Nat Commun, 6, 2015
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