6QX3
 
 | | Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 | | 分子名称: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | 登録日 | 2019-03-07 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
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8AAA
 | | Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide | | 分子名称: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, Spike protein S1, Stapled peptide | | 著者 | Brear, P, Chen, L, Gaynor, K, Harman, M, Dods, R, Hyvonen, M. | | 登録日 | 2022-06-30 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Nat Commun, 14, 2023
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7Z8O
 | | Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide | | 分子名称: | 2,4,6-tris(chloromethyl)-1,3,5-triazine, GLYCEROL, Spike protein S1, ... | | 著者 | Brear, P, Chen, L, Gaynor, K, Harman, M, Dods, R, Hyvonen, M. | | 登録日 | 2022-03-18 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Nat Commun, 14, 2023
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6XZG
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 | | 分子名称: | Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-04 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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7S1C
 | | Crystal structure of E.coli DsbA in complex with compound MIPS-0001897 (compound 1) | | 分子名称: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-3-ylphenyl)methanamine | | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Sharma, P. | | 登録日 | 2021-09-02 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates
Chemrxiv, 2022
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7S1L
 | | Crystal structure of E.coli DsbA in complex with compound MIPS-0001896 (compound 72) | | 分子名称: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, methyl cis-4-({[3-(thiophen-3-yl)benzyl]amino}methyl)cyclohexanecarboxylate | | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | | 登録日 | 2021-09-02 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.623 Å) | | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates
Chemrxiv, 2022
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7S1D
 | | Crystal structure of E.coli DsbA in complex with compound MIPS-0001877 (compound 39) | | 分子名称: | 1-[3-(thiophen-3-yl)benzyl]piperidin-2-one, COPPER (II) ION, Thiol:disulfide interchange protein DsbA | | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | | 登録日 | 2021-09-02 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates
Chemrxiv, 2022
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7S1F
 | | Crystal structure of E.coli DsbA in complex with compound MIPS-0001886 (compound 38) | | 分子名称: | 1-[(3-thiophen-3-ylphenyl)methyl]-3~{H}-pyrrol-2-one, COPPER (II) ION, GLYCEROL, ... | | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | | 登録日 | 2021-09-02 | | 公開日 | 2023-02-08 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates
Chemrxiv, 2022
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6XZR
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 1 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6XZP
 | | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 4 | | 分子名称: | LRRcap domain-containing protein, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6Y0C
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 2 | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*GP*CP*CP*UP*UP*UP*U)-3'), ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-07 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6XZQ
 | | Influenza C virus polymerase in complex with human ANP32A - Subclass 1 | | 分子名称: | Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Fan, H, Carrique, L, Keown, J.R, Grimes, J.M, Fodor, E. | | 登録日 | 2020-02-05 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020
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6RR7
 | | Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... | | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | | 登録日 | 2019-05-17 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
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6F5O
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6F5P
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