8B0U
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821P
| THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLYCINE-12 MUTANT OF P21H-RAS | 分子名称: | C-H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Scheidig, A.J, Krengel, U, Pai, E.F, Kabsch, W, Wittinghofer, A, Goody, R.S. | 登録日 | 1993-03-29 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras. Biochemistry, 32, 1993
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7KN5
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobodies VHH E and U | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2024-11-20 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7KSG
| SARS-CoV-2 spike in complex with nanobodies E | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 glycoprotein, Spike glycoprotein | 著者 | Hallberg, B.M, Das, H. | 登録日 | 2020-11-22 | 公開日 | 2021-01-20 | 最終更新日 | 2024-10-30 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7KN7
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7KN6
| Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CC12.3 Fab heavy chain, CC12.3 Fab light chain, ... | 著者 | Liu, H, Yuan, M, Zhu, X, Wu, N.C, Wilson, I.A. | 登録日 | 2020-11-04 | 公開日 | 2021-01-20 | 最終更新日 | 2024-11-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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7B17
| SARS-CoV-spike RBD bound to two neutralising nanobodies. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama,SARS-CoV-2 neutralizing biparatopic nanobody VE,nanobody E from Lama glama, Spike protein S1 | 著者 | Hallberg, B.M, Das, H. | 登録日 | 2020-11-23 | 公開日 | 2021-02-10 | 最終更新日 | 2024-10-23 | 実験手法 | ELECTRON MICROSCOPY (4.01 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape Science, 371, 2021
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7B14
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7B18
| SARS-CoV-spike bound to two neutralising nanobodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody against SARS-CoV-2 VHH E, ... | 著者 | Hallberg, B.M, Das, H. | 登録日 | 2020-11-24 | 公開日 | 2021-04-28 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science, 371, 2021
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1RAX
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7QE5
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7QDA
| Crystal structure of CalpL | 分子名称: | CalpL, SULFATE ION, TETRAETHYLENE GLYCOL, ... | 著者 | Schneberger, N, Hagelueken, G. | 登録日 | 2021-11-26 | 公開日 | 2022-11-16 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antiviral signalling by a cyclic nucleotide activated CRISPR protease. Nature, 614, 2023
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1CLU
| H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP | 分子名称: | 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1 | 著者 | Ahmadian, M.R, Zor, T, Vogt, D, Kabsch, W, Selinger, Z, Wittinghofer, A, Scheffzek, K. | 登録日 | 1999-05-03 | 公開日 | 1999-05-28 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Guanosine triphosphatase stimulation of oncogenic Ras mutants. Proc.Natl.Acad.Sci.USA, 96, 1999
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1F5N
| HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP. | 分子名称: | INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Prakash, B, Renault, L, Praefcke, G.J.K, Herrmann, C, Wittinghofer, A. | 登録日 | 2000-06-15 | 公開日 | 2000-09-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Triphosphate structure of guanylate-binding protein 1 and implications for nucleotide binding and GTPase mechanism. EMBO J., 19, 2000
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1DG3
| STRUCTURE OF HUMAN GUANYLATE BINDING PROTEIN-1 IN NUCLEOTIDE FREE FORM | 分子名称: | PROTEIN (INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1) | 著者 | Prakash, B, Praefcke, G.J.K, Renault, L, Wittinghofer, A, Herrmann, C. | 登録日 | 1999-11-23 | 公開日 | 2000-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins. Nature, 403, 2000
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1RVD
| H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP | 分子名称: | 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, TRANSFORMING PROTEIN P21/H-RAS-1 | 著者 | Ahmadian, M.R, Zor, T, Vogt, D, Kabsch, W, Selinger, Z, Wittinghofer, A, Scheffzek, K. | 登録日 | 1999-05-03 | 公開日 | 1999-05-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Guanosine triphosphatase stimulation of oncogenic Ras mutants. Proc.Natl.Acad.Sci.USA, 96, 1999
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2B3A
| Solution structure of the Ras-binding domain of the Ral Guanosine Dissociation Stimulator | 分子名称: | Ral guanine nucleotide dissociation stimulator | 著者 | Gronwald, W, Maurer, T, Fuechsl, R, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R. | 登録日 | 2005-09-20 | 公開日 | 2006-09-26 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | New insights into binding of the possible cancer target RalGDS To be Published
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