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7BIR
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BU of 7bir by Molmil
Inhibitor of MDM2-p53 Interaction
分子名称: 1-[[(1~{R})-2-[(5-chloranylpyridin-2-yl)methyl]-1-(4-chlorophenyl)-7-fluoranyl-3-oxidanylidene-5-(2-oxidanylpropan-2-yl)isoindol-1-yl]oxymethyl]cyclopropane-1-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION
著者Williams, P.A.
登録日2021-01-13
公開日2021-04-07
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.
J.Med.Chem., 64, 2021
8V9J
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BU of 8v9j by Molmil
Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ...
著者Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G.
登録日2023-12-08
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8V9K
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BU of 8v9k by Molmil
Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ...
著者Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G.
登録日2023-12-08
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8V9L
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BU of 8v9l by Molmil
Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ...
著者Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G.
登録日2023-12-08
公開日2024-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
6GKI
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BU of 6gki by Molmil
Structure of E coli MlaC in Variously Loaded States
分子名称: BROMIDE ION, GLYCEROL, Probable phospholipid-binding protein MlaC
著者Knowles, T.J, Lovering, A.L.
登録日2018-05-21
公開日2019-04-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system.
Nat Microbiol, 4, 2019
8RDV
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BU of 8rdv by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon, mRNA and P-site tRNA (structure 2).
分子名称: 16S rRNA, 23S rRNA, 5S rRNA, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-08
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8RD8
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BU of 8rd8 by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factors Balon and RaiA (structure 1).
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S30, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-07
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
8RDW
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BU of 8rdw by Molmil
Cryo-EM structure of P. urativorans 70S ribosome in complex with hibernation factor Balon and EF-Tu(GDP) (structure 3).
分子名称: 16S rRNA, 23S rRNA, 5S rRNA, ...
著者Helena-Bueno, K, Rybak, M.Y, Gagnon, M.G, Hill, C.H, Melnikov, S.V.
登録日2023-12-08
公開日2024-02-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.74 Å)
主引用文献A new family of bacterial ribosome hibernation factors.
Nature, 626, 2024
3LN4
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BU of 3ln4 by Molmil
Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2
分子名称: 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ...
著者Theodossis, A, Gras, S, Rossjohn, J.
登録日2010-02-01
公開日2010-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.296 Å)
主引用文献The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
3LN5
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BU of 3ln5 by Molmil
Crystal structure of HLA-B*4104 in complex with a 11mer self-peptide derived from S-methyl-5-thioadenosine phosphorylase
分子名称: 11-mer peptide from S-methyl-5'-thioadenosine phosphorylase, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Theodossis, A, Gras, S, Rossjohn, J.
登録日2010-02-02
公開日2010-10-20
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family
Haematologica, 96, 2011
4COS
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BU of 4cos by Molmil
Crystal structure of the PHD-Bromo-PWWP cassette of human PRKCBP1
分子名称: 1,4-DIETHYLENE DIOXIDE, PROTEIN KINASE C-BINDING PROTEIN 1, ZINC ION
著者Krojer, T, Savitsky, P, Newman, J.A, Cooper, C.D.O, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Filippakopoulos, P.
登録日2014-01-30
公開日2014-03-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Multivalent Histone and DNA Engagement by a PHD/BRD/PWWP Triple Reader Cassette Recruits ZMYND8 to K14ac-Rich Chromatin.
Cell Rep, 17, 2016
1ARJ
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BU of 1arj by Molmil
ARG-BOUND TAR RNA, NMR
分子名称: ARGININE, TAR RNA
著者Aboul-Ela, F, Varani, G, Karn, J.
登録日1995-08-30
公開日1996-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of the human immunodeficiency virus type-1 TAR RNA reveals principles of RNA recognition by Tat protein.
J.Mol.Biol., 253, 1995
1ANR
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BU of 1anr by Molmil
CIS-ACTING RNA REGULATORY ELEMENT (HIV-1 TAR), NMR, 20 STRUCTURES
分子名称: RNA REGULATORY ELEMENT TAR
著者Aboul-Ela, F, Varani, G, Karn, J.
登録日1996-07-06
公開日1997-01-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of HIV-1 TAR RNA in the absence of ligands reveals a novel conformation of the trinucleotide bulge.
Nucleic Acids Res., 24, 1996
1IBR
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BU of 1ibr by Molmil
COMPLEX OF RAN WITH IMPORTIN BETA
分子名称: GTP-binding nuclear protein RAN, Importin beta-1 subunit, MAGNESIUM ION, ...
著者Vetter, I.R, Arndt, A, Kutay, U, Goerlich, D, Wittinghofer, A.
登録日1999-05-14
公開日1999-06-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural view of the Ran-Importin beta interaction at 2.3 A resolution
Cell(Cambridge,Mass.), 97, 1999
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