8PPD
 
 | | Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with DL-6-deoxy-6-hydroxy-methyl-scyllo-inositol 1,2,4-trisphosphate/ATP/Mn | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DL-6-deoxy-6-hydroxy-methyl-scyllo-inositol 1,2,4-trisphosphate, Inositol-trisphosphate 3-kinase A, ... | | 著者 | Marquez-Monino, M.A, Gonzalez, B. | | 登録日 | 2023-07-07 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.
Nat Commun, 15, 2024
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8PPH
 | | Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with alpha-D-glucopyranosyl 1,3,4-trisphosphate/ATP/Mn | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Inositol-trisphosphate 3-kinase A, MANGANESE (II) ION, ... | | 著者 | Marquez-Monino, M.A, Gonzalez, B. | | 登録日 | 2023-07-07 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Substrate promiscuity of inositol 1,4,5-trisphosphate kinase driven by structurally-modified ligands and active site plasticity.
Nat Commun, 15, 2024
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5CU7
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5CX4
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4AXD
 | | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with AMPPNP | | 分子名称: | CITRIC ACID, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | | 登録日 | 2012-06-12 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference
J.Biol.Chem., 287, 2012
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4AXE
 | | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase in complex with ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... | | 著者 | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | | 登録日 | 2012-06-12 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference
J.Biol.Chem., 287, 2012
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4AXC
 | | Inositol 1,3,4,5,6-pentakisphosphate 2-kinase apo form | | 分子名称: | GLYCEROL, INOSITOL-PENTAKISPHOSPHATE 2-KINASE, SULFATE ION, ... | | 著者 | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | | 登録日 | 2012-06-12 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference
J.Biol.Chem., 287, 2012
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4AXF
 | | InsP5 2-K in complex with Ins(3,4,5,6)P4 plus AMPPNP | | 分子名称: | INOSITOL-PENTAKISPHOSPHATE 2-KINASE, Myo inositol 3,4,5,6 tetrakisphosphate, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | I Banos-Sanz, J, Sanz-Aparicio, J, Gonzalez, B. | | 登録日 | 2012-06-12 | | 公開日 | 2012-07-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Conformational Changes Undergone by Inositol 1,3,4,5,6-Pentakisphosphate 2-Kinase Upon Substrate Binding: The Role of N-Lobe and Enantiomeric Substrate Preference
J.Biol.Chem., 287, 2012
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