6POS
| ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | 登録日 | 2019-07-05 | 公開日 | 2020-03-11 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PO1
| ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 4 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | 登録日 | 2019-07-03 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PP8
| ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | 登録日 | 2019-07-05 | 公開日 | 2020-03-11 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PP6
| ClpX in ClpX-ClpP complex bound to substrate and ATP-gamma-S, class 3 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Fei, X, Jenni, S, Harrison, S.C, Sauer, R.T. | 登録日 | 2019-07-05 | 公開日 | 2020-03-11 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.28 Å) | 主引用文献 | Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate. Elife, 9, 2020
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6PXI
| The crystal structure of a singly capped HslUV complex with an axial pore plug and a HslU E257Q mutation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | 著者 | Baytshtok, V, Grant, R.A, Sauer, R.T. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.447 Å) | 主引用文献 | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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4RQZ
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4RR0
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4RQY
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4RR1
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6PXL
| 3.74 Angstroms resolution structure of HlsU with an axial-channel plug | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, MAGNESIUM ION, ... | 著者 | Baytshtok, V, Grant, R.A, Sauer, R.T. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.741 Å) | 主引用文献 | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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6PXK
| 3.65 Angstroms resolution structure of HslU with an axial-channel plug | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, SULFATE ION, ... | 著者 | Baytshtok, V, Grant, R.A, Sauer, R.T. | 登録日 | 2019-07-26 | 公開日 | 2020-07-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.647 Å) | 主引用文献 | Heat activates the AAA+ HslUV protease by melting an axial autoinhibitory plug. Cell Rep, 34, 2021
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5JI2
| HslU L199Q in HslUV complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV, ... | 著者 | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | 登録日 | 2016-04-21 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.307 Å) | 主引用文献 | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis. Structure, 24, 2016
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5JI3
| HslUV complex | 分子名称: | 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU, ATP-dependent protease subunit HslV | 著者 | Grant, R.A, Sauer, R.T, Schmitz, K.R, Baytshtok, V. | 登録日 | 2016-04-21 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A Structurally Dynamic Region of the HslU Intermediate Domain Controls Protein Degradation and ATP Hydrolysis. Structure, 24, 2016
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6WR2
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6WRF
| ClpX-ClpP complex bound to GFP-ssrA, recognition complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Fei, X, Sauer, R.T. | 登録日 | 2020-04-29 | 公開日 | 2020-11-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates. Elife, 9, 2020
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6WSG
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8ET3
| Cryo-EM structure of a delivery complex containing the SspB adaptor, an ssrA-tagged substrate, and the AAA+ ClpXP protease | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent Clp protease ATP-binding subunit ClpX, ATP-dependent Clp protease proteolytic subunit, ... | 著者 | Ghanbarpour, A, Fei, X, Davis, J.H, Sauer, R.T. | 登録日 | 2022-10-16 | 公開日 | 2023-01-25 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The SspB adaptor drives structural changes in the AAA+ ClpXP protease during ssrA-tagged substrate delivery. Proc.Natl.Acad.Sci.USA, 120, 2023
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5TXV
| HslU P21 cell with 4 hexamers | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent protease ATPase subunit HslU | 著者 | Grant, R.A, Chen, J, Glynn, S.E, Sauer, R.T. | 登録日 | 2016-11-17 | 公開日 | 2017-03-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (7.086 Å) | 主引用文献 | Covalently linked HslU hexamers support a probabilistic mechanism that links ATP hydrolysis to protein unfolding and translocation. J. Biol. Chem., 292, 2017
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