6IVX
 
 | | Discovery of the Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold. | | 分子名称: | (4S)-4-[4'-cyclopropyl-5-(2,2-dimethylpropyl)[3,5'-bi-1,2-oxazol]-3'-yl]-6-[(2,4-dichlorophenyl)amino]-6-oxohexanoic acid, Nuclear receptor ROR-gamma, Nuclear receptor corepressor 2 | | 著者 | Noguchi, M, Nomura, A, Doi, S, Adachi, T. | | 登録日 | 2018-12-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Discovery of Second Generation ROR gamma Inhibitors Composed of an Azole Scaffold.
J. Med. Chem., 62, 2019
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6KD5
 | | Crystal structure of the extracellular domain of MSPL/TMPRSS13 in complex with dec-RVKR-cmk inhibitor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DECANOYL-ARG-VAL-LYS-ARG-CHLOROMETHYLKETONE INHIBITOR, ... | | 著者 | Ohno, A, Maita, N, Okumura, Y, Nikawa, T. | | 登録日 | 2019-06-30 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of inhibitor-bound human MSPL that can activate high pathogenic avian influenza.
Life Sci Alliance, 4, 2021
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1CYC
 | | THE CRYSTAL STRUCTURE OF BONITO (KATSUO) FERROCYTOCHROME C AT 2.3 ANGSTROMS RESOLUTION. II. STRUCTURE AND FUNCTION | | 分子名称: | FERROCYTOCHROME C, HEME C | | 著者 | Tanaka, N, Yamane, T, Tsukihara, T, Ashida, T, Kakudo, M. | | 登録日 | 1976-08-01 | | 公開日 | 1976-10-06 | | 最終更新日 | 2021-03-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The crystal structure of bonito (katsuo) ferrocytochrome c at 2.3 A resolution. II. Structure and function.
J.Biochem.(Tokyo), 77, 1975
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5H5L
 | | Structure of prostaglandin synthase D of Nilaparvata lugens | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLUTATHIONE, ... | | 著者 | Yamamoto, K, Higashiura, A, Suzuki, S, Nakagawa, A. | | 登録日 | 2016-11-07 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | | 主引用文献 | Molecular structure of a prostaglandin D synthase requiring glutathione from the brown planthopper, Nilaparvata lugens
Biochem. Biophys. Res. Commun., 492, 2017
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6KAW
 | | Crystal structure of CghA | | 分子名称: | CghA | | 著者 | Hara, K, Hashimoto, H, Yokoyama, M, Sato, M, Watanabe, K. | | 登録日 | 2019-06-24 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase
Nat Catal, 2021
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6KBC
 | | Crystal structure of CghA with Sch210972 | | 分子名称: | (2S)-3-[(2S,4E)-4-[[(1R,2S,4aR,6S,8R,8aS)-2-[(E)-but-2-en-2-yl]-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-oxidanyl-methylidene]-3,5-bis(oxidanylidene)pyrrolidin-2-yl]-2-methyl-2-oxidanyl-propanoic acid, CghA | | 著者 | Hara, K, Hashimoto, H, Maeda, N, Sato, M, Watanabe, K. | | 登録日 | 2019-06-24 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Catalytic mechanism and endo-to-exo selectivity reversion of an octalin-forming natural Diels-Alderase
Nat Catal, 2021
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2KTD
 | | Solution structure of mouse lipocalin-type prostaglandin D synthase / substrate analog (U-46619) complex | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Prostaglandin-H2 D-isomerase | | 著者 | Shimamoto, S, Maruo, H, Yoshida, T, Kato, N, Ohkubo, T. | | 登録日 | 2010-01-27 | | 公開日 | 2011-02-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of Lipocalin-type Prostaglandin D synthase / Substrate analog complex reveals Open-Closed Conformational Change required for Substrate Recognition
To be Published
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3VPT
 | | Crystal structure of Bombyx mori sigma-class glutathione transferase in apo form | | 分子名称: | DI(HYDROXYETHYL)ETHER, Glutathione S-transferase sigma, S-1,2-PROPANEDIOL, ... | | 著者 | Yamamoto, K, Higashiura, A, Suzuki, M, Nakagawa, A. | | 登録日 | 2012-03-13 | | 公開日 | 2013-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity
Biochim.Biophys.Acta, 1830, 2013
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3VPQ
 | | Crystal structure of Bombyx mori sigma-class glutathione transferase in complex with glutathione | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLUTATHIONE, Glutathione S-transferase sigma, ... | | 著者 | Yamamoto, K, Higashiura, A, Nakagawa, A, Suzuki, M. | | 登録日 | 2012-03-08 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | | 主引用文献 | Crystal structure of a Bombyx mori sigma-class glutathione transferase exhibiting prostaglandin E synthase activity
Biochim.Biophys.Acta, 1830, 2013
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2TAA
 | | STRUCTURE AND POSSIBLE CATALYTIC RESIDUES OF TAKA-AMYLASE A | | 分子名称: | CALCIUM ION, TAKA-AMYLASE A | | 著者 | Kusunoki, M, Matsuura, Y, Tanaka, N, Kakudo, M. | | 登録日 | 1982-10-18 | | 公開日 | 1982-10-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure and possible catalytic residues of Taka-amylase A
J.Biochem.(Tokyo), 95, 1984
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3VI7
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3VI5
 | | Human hematopoietic prostaglandin D synthase inhibitor complex structures | | 分子名称: | 1-amino-9,10-dioxo-4-[(4-sulfamoylphenyl)amino]-9,10-dihydroanthracene-2-sulfonic acid, CALCIUM ION, GLUTATHIONE, ... | | 著者 | Kado, Y, Inoue, T. | | 登録日 | 2011-09-21 | | 公開日 | 2012-04-18 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Human hematopoietic prostaglandin D synthase inhibitor complex structures
J.Biochem., 151, 2012
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