4KR0
 
 | | Complex structure of MERS-CoV spike RBD bound to CD26 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4, ... | | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | | 登録日 | 2013-05-15 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26.
Nature, 500, 2013
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6UZ4
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6UZ5
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3J3W
 | | Atomic model of the immature 50S subunit from Bacillus subtilis (state II-a) | | 分子名称: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | | 登録日 | 2013-04-28 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (10.7 Å) | | 主引用文献 | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
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3J3V
 | | Atomic model of the immature 50S subunit from Bacillus subtilis (state I-a) | | 分子名称: | 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... | | 著者 | Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. | | 登録日 | 2013-04-28 | | 公開日 | 2013-06-12 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (13.3 Å) | | 主引用文献 | Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit
Nucleic Acids Res., 41, 2013
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3MIL
 | | Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae | | 分子名称: | GLYCEROL, Isoamyl acetate-hydrolyzing esterase | | 著者 | Ma, J, Lu, Q, Yuan, Y, Li, K, Ge, H, Go, Y, Niu, L, Teng, M. | | 登録日 | 2010-04-11 | | 公開日 | 2010-11-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of isoamyl acetate-hydrolyzing esterase from Saccharomyces cerevisiae reveals a novel active site architecture and the basis of substrate specificity
Proteins, 79, 2011
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3NB6
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2MZK
 | | The solution structure of the Magnesium-bound Conantokin RLB | | 分子名称: | Conantokin-R1-B | | 著者 | Kunda, S, Yuan, Y, Balsara, R.D, Zajicek, J, Castellino, F.J. | | 登録日 | 2015-02-14 | | 公開日 | 2015-06-17 | | 最終更新日 | 2015-08-05 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
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2MYZ
 | | The Solution Structure of the Magnesium-bound Conantokin-R1B Mutant | | 分子名称: | Conantokin-R1-B | | 著者 | Kunda, S, Yuan, Y, Balsara, R.D, Zajicek, J, Castellino, F.J. | | 登録日 | 2015-02-04 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
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2MZM
 | | The Solution Structure of the Magnesium-bound Conantokin-G | | 分子名称: | Conantokin-R1-B | | 著者 | Kunda, S, Yuan, Y, Balsara, R.D, Zajicek, J, Castellino, F.J. | | 登録日 | 2015-02-14 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
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2MZL
 | | The Solution Structure of the Magnesium-bound Conantokin-G Mutant | | 分子名称: | Conantokin-R1-B | | 著者 | Kunda, S, Yuan, Y, Balsara, R.D, Zajicek, J, Castellino, F.J. | | 登録日 | 2015-02-14 | | 公開日 | 2015-06-17 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
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7YR7
 | | Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with three RsmA protein dimers | | 分子名称: | RsmZ RNA (118-MER), Translational regulator CsrA | | 著者 | Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Liu, L, Ling, X, Yang, X, Wu, Y, Liu, T, Miao, Z, Wei, X, Bujnicki, J.M, Zhao, K, Su, Z. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence.
Cell Res., 33, 2023
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7YR6
 | | Cryo-EM structure of Pseudomonas aeruginosa RsmZ RNA in complex with two RsmA protein dimers | | 分子名称: | RsmZ RNA, Translational regulator CsrA | | 著者 | Jia, X, Pan, Z, Yuan, Y, Luo, B, Luo, Y, Mukherjee, S, Jia, G, Ling, X, Yang, X, Wu, Y, Liu, T, Wei, X, Bujnick, J.M, Zhao, K, Su, Z. | | 登録日 | 2022-08-09 | | 公開日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Structural basis of sRNA RsmZ regulation of Pseudomonas aeruginosa virulence.
Cell Res., 33, 2023
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7Y6I
 | | Cryo-EM structure of human sodium-chloride cotransporter | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Nan, J, Yang, X, Shan, Z, Yuan, Y, Zhang, Y.Q. | | 登録日 | 2022-06-20 | | 公開日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | | 主引用文献 | Cryo-EM structure of the human sodium-chloride cotransporter NCC.
Sci Adv, 8, 2022
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7Y7Y
 | | Cryo-EM structure of human GABA transporter GAT1 bound with nipecotic acid in NaCl solution in an inward-occluded state at 2.4 angstrom | | 分子名称: | (3R)-piperidine-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2022-06-22 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
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7Y7W
 | | Cryo-EM structure of human GABA transporter GAT1 bound with GABA in NaCl solution in an inward-occluded state at 2.4 angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ... | | 著者 | Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2022-06-22 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
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7Y7Z
 | | Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Sodium- and chloride-dependent GABA transporter 1, ... | | 著者 | Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2022-06-22 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
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7Y7V
 | | Cryo-EM structure of human apo GABA transporter GAT1 in an inward-open state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Sodium- and chloride-dependent GABA transporter 1 | | 著者 | Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2022-06-22 | | 公開日 | 2023-04-26 | | 最終更新日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
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6LZ0
 | | Cryo-EM structure of human MCT1 in complex with Basigin-2 in the presence of lactate | | 分子名称: | (2S)-2-HYDROXYPROPANOIC ACID, Basigin, Monocarboxylate transporter 1 | | 著者 | Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C. | | 登録日 | 2020-02-16 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
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6LYY
 | | Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate AZD3965 in the outward-open conformation. | | 分子名称: | 3-methyl-5-[[(4~{R})-4-methyl-4-oxidanyl-1,2-oxazolidin-2-yl]carbonyl]-6-[[5-methyl-3-(trifluoromethyl)-1~{H}-pyrazol-4-yl]methyl]-1-propan-2-yl-thieno[2,3-d]pyrimidine-2,4-dione, Basigin, Monocarboxylate transporter 1 | | 著者 | Wang, N, Jiang, X, Zhang, S, Zhu, A, Yuan, Y, Lei, J, Yan, C. | | 登録日 | 2020-02-16 | | 公開日 | 2020-12-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Cell, 184, 2021
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6BZK
 | | Solution structure of KTI55 | | 分子名称: | M protein | | 著者 | Castellino, F.J, Qiu, C, Yuan, Y. | | 登録日 | 2017-12-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
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6BZL
 | | Solution structure of VEK75 | | 分子名称: | M protein | | 著者 | Qiu, C, Yuan, Y, Castellino, F.J. | | 登録日 | 2017-12-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
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8HNC
 | | Cryo-EM structure of human OATP1B1 in complex with bilirubin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-2-[[5-[(Z)-(3-ethenyl-4-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1H-pyrrol-2-yl]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, ... | | 著者 | Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y. | | 登録日 | 2022-12-07 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023
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8HND
 | | Cryo-EM structure of human OATP1B1 in complex with estrone-3-sulfate | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier organic anion transporter family member 1B1, ... | | 著者 | Shan, Z, Yang, X, Liu, H, Nan, J, Yuan, Y, Zhang, Y. | | 登録日 | 2022-12-07 | | 公開日 | 2023-09-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Cryo-EM structures of human organic anion transporting polypeptide OATP1B1.
Cell Res., 33, 2023
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8HFF
 | | Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom. | | 分子名称: | L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter | | 著者 | Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. | | 登録日 | 2022-11-10 | | 公開日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Molecular basis for the reuptake and inhibition of human norepinephrine transporter
To Be Published
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