7F8K
| |
3VHV
| Mineralocorticoid receptor ligand-binding domain with non-steroidal antagonist | 分子名称: | 1,2-ETHANEDIOL, 6-[(1E)-2-phenyl-N-(3-sulfanyl-4H-1,2,4-triazol-4-yl)ethanimidoyl]-2H-1,4-benzoxazin-3(4H)-one, 6-[(7S)-7-phenyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-6-yl]-2H-1,4-benzoxazin-3(4H)-one, ... | 著者 | Sogabe, S, Habuka, N. | 登録日 | 2011-09-07 | 公開日 | 2011-12-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Identification of Benzoxazin-3-one Derivatives as Novel, Potent, and Selective Nonsteroidal Mineralocorticoid Receptor Antagonists J.Med.Chem., 54, 2011
|
|
1ETN
| |
3KC6
| |
3KHW
| |
6A78
| Crystal structure of the fifth immunoglobulin domain (Ig5) of human Robo1 in complex with the scFv fragment of murine monoclonal antibody B5209B | 分子名称: | Heavy chain and linker region of the anti-human Robo1 antibody B5209B scFv, Light chain region of the anti-human Robo1 antibody B5209B scFv, Roundabout homolog 1, ... | 著者 | Mizohata, E, Nakayama, T, Kado, Y, Inoue, T. | 登録日 | 2018-07-02 | 公開日 | 2019-01-30 | 最終更新日 | 2019-03-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Affinity Improvement of a Cancer-Targeted Antibody through Alanine-Induced Adjustment of Antigen-Antibody Interface. Structure, 27, 2019
|
|
8DMY
| Cryo-EM structure of cardiac muscle alpha-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-09 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
|
|
8DNF
| Cryo-EM structure of nonmuscle gamma-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 2, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-11 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
|
|
8DMX
| Cryo-EM structure of skeletal muscle alpha-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-08 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
|
|
8DNH
| Cryo-EM structure of nonmuscle beta-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... | 著者 | Arora, A.S, Huang, H.L, Heissler, S.M, Chinthalapudi, K. | 登録日 | 2022-07-11 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Structural insights into actin isoforms. Elife, 12, 2023
|
|
2D7G
| Crystal structure of the aa complex of the N-terminal domain of PriA | 分子名称: | DNA (5'-D(P*AP*A)-3'), Primosomal protein N' | 著者 | Sasaki, K, Ose, T, Maenaka, K, Masai, H, Kohda, D. | 登録日 | 2005-11-21 | 公開日 | 2006-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA. EMBO J., 26, 2007
|
|
2D7H
| Crystal structure of the ccc complex of the N-terminal domain of PriA | 分子名称: | DNA (5'-D(P*CP*CP*C)-3'), Primosomal protein N' | 著者 | Sasaki, K, Ose, T, Maenaka, K, Masai, H, Kohda, D. | 登録日 | 2005-11-21 | 公開日 | 2006-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA. EMBO J., 26, 2007
|
|
2D7E
| Crystal structure of N-terminal domain of PriA from E.coli | 分子名称: | Primosomal protein N' | 著者 | Sasaki, K, Ose, T, Maenaka, K, Masai, H, Kohda, D. | 登録日 | 2005-11-18 | 公開日 | 2006-11-07 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of the 3'-end recognition of a leading strand in stalled replication forks by PriA. EMBO J., 26, 2007
|
|
1ETL
| |
6LYC
| Crystal structure of the NOD SIRPa complex with D4-2 | 分子名称: | ACETIC ACID, D4-2, SIRPa of the NOD mouse strain | 著者 | Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. | 登録日 | 2020-02-14 | 公開日 | 2020-07-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol, 27, 2020
|
|
1ETM
| |
5K5B
| Wild-type PAS-GAF fragment from Deinococcus radiodurans BphP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, ACETATE ION, ... | 著者 | Takala, H, Edlund, P, Claesson, E, Ihalainen, J.A, Westenhoff, S. | 登録日 | 2016-05-23 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography. Sci Rep, 6, 2016
|
|
6Y7A
| X-ray structure of the Haloalkane dehalogenase HaloTag7 labeled with a chloroalkane-tetramethylrhodamine fluorophore substrate | 分子名称: | CHLORIDE ION, GLYCEROL, Haloalkane dehalogenase, ... | 著者 | Tarnawski, M, Johnsson, K, Hiblot, J. | 登録日 | 2020-02-28 | 公開日 | 2021-03-31 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60, 2021
|
|
6Y7B
| X-ray structure of the Haloalkane dehalogenase HaloTag7 labeled with a chloroalkane-carbopyronine fluorophore substrate | 分子名称: | 4-[2-[2-(6-chloranylhexoxy)ethoxy]ethylcarbamoyl]-2-[3-(dimethylamino)-6-(dimethyl-$l^{4}-azanylidene)-10,10-dimethyl-anthracen-9-yl]benzoic acid, CHLORIDE ION, Haloalkane dehalogenase | 著者 | Tarnawski, M, Johnsson, K, Hiblot, J. | 登録日 | 2020-02-28 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60, 2021
|
|
6PU2
| Dark, Mutant H275T , 100K, PCM Myxobacterial Phytochrome, P2 | 分子名称: | 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, Photoreceptor-histidine kinase BphP | 著者 | Pandey, S, Schmidt, M, Stojkovic, E.A. | 登録日 | 2019-07-16 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures. Struct Dyn., 6, 2019
|
|
6PTQ
| Dark, Room Temperature, PCM Myxobacterial Phytochrome, P2, Wild Type | 分子名称: | 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, BENZAMIDINE, Photoreceptor-histidine kinase BphP | 著者 | Pandey, S, Schmidt, M, Stojkovic, E.A. | 登録日 | 2019-07-16 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures. Struct Dyn., 6, 2019
|
|
6PTX
| Dark, 100K, PCM Myxobacterial Phytochrome, P2, Wild Type, | 分子名称: | 3-[(2Z)-2-({3-(2-carboxyethyl)-5-[(E)-(4-ethenyl-3-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl}methylidene)-5-{(Z)-[(3E,4S)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene]methyl}-4-methyl-2H-pyrrol-3-yl]propanoic acid, Photoreceptor-histidine kinase BphP | 著者 | Pandey, S, Schmidt, M, Stojkovic, E.A. | 登録日 | 2019-07-16 | 公開日 | 2019-10-09 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | High-resolution crystal structures of a myxobacterial phytochrome at cryo and room temperatures. Struct Dyn., 6, 2019
|
|
3RCD
| HER2 Kinase Domain Complexed with TAK-285 | 分子名称: | N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide, Receptor tyrosine-protein kinase erbB-2 | 著者 | Aertgeerts, K, Skene, R, Sogabe, S. | 登録日 | 2011-03-30 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | 主引用文献 | Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold. J.Med.Chem., 54, 2011
|
|
6ZCC
| X-ray structure of the Haloalkane dehalogenase HOB (HaloTag7-based Oligonucleotide Binder) labeled with a chloroalkane-tetramethylrhodamine fluorophore substrate | 分子名称: | ACETATE ION, CALCIUM ION, Haloalkane dehalogenase, ... | 著者 | Tarnawski, M, Johnsson, K, Hiblot, J. | 登録日 | 2020-06-10 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Kinetic and Structural Characterization of the Self-Labeling Protein Tags HaloTag7, SNAP-tag, and CLIP-tag. Biochemistry, 60, 2021
|
|
7YOW
| |