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6MZJ
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BU of 6mzj by Molmil
Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer, 2 Fabs bound, sharpened map
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 426c DS-SOSIP D3, ...
著者Borst, A.J, Weidle, C.E, Gray, M.D, Frenz, B, Snijder, J, Joyce, M.G, Georgiev, I.S, Stewart-Jones, G.B.E, Kwong, P.D, McGuire, A.T, DiMaio, F, Stamatatos, L, Pancera, M, Veesler, D.
登録日2018-11-05
公開日2018-11-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core.
Elife, 7, 2018
7PHC
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BU of 7phc by Molmil
70S ribosome with A*- and P/E-site tRNAs in chloramphenicol-treated Mycoplasma pneumoniae cells
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
登録日2021-08-16
公開日2022-05-25
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (9.9 Å)
主引用文献Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
7PHB
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BU of 7phb by Molmil
70S ribosome with A- and P-site tRNAs in chloramphenicol-treated Mycoplasma pneumoniae cells
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
登録日2021-08-16
公開日2022-05-25
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
1SVY
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BU of 1svy by Molmil
SEVERIN DOMAIN 2, 1.75 ANGSTROM CRYSTAL STRUCTURE
分子名称: CALCIUM ION, SEVERIN, SODIUM ION
著者Puius, Y.A, Fedorov, E.V, Eichinger, L, Sullivan, M, Schleicher, M, Almo, S.C.
登録日1998-08-10
公開日1999-08-10
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mapping the functional surface of domain 2 in the gelsolin superfamily.
Biochemistry, 39, 2000
6N7M
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BU of 6n7m by Molmil
1.78 Angstrom Resolution Crystal Structure of Hypothetical Protein CD630_05490 from Clostridioides difficile 630.
分子名称: Hypothetical Protein CD630_05490
著者Minasov, G, Shuvalova, L, Wawrzak, Z, Kiryukhina, O, Dubrovska, I, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-11-27
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献1.78 Angstrom Resolution Crystal Structure of Hypothetical Protein CD630_05490 from Clostridioides difficile 630.
To Be Published
7PH9
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BU of 7ph9 by Molmil
70S ribosome with P-site tRNA in chloramphenicol-treated Mycoplasma pneumoniae cells
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Xue, L, Lenz, S, Rappsilber, J, Mahamid, J.
登録日2021-08-16
公開日2022-05-25
最終更新日2022-10-19
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献Visualizing translation dynamics at atomic detail inside a bacterial cell.
Nature, 610, 2022
6N86
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BU of 6n86 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein
分子名称: Synembryn-A
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6N8P
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BU of 6n8p by Molmil
Crystal structure of the human cell polarity protein Lethal Giant Larvae 2 (Lgl2). Unphosphorylated, crystal form 1.
分子名称: CHLORIDE ION, Lethal(2) giant larvae protein homolog 2
著者Almagor, L, Weis, W.I.
登録日2018-11-30
公開日2019-05-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.193 Å)
主引用文献Structural insights into the aPKC regulatory switch mechanism of the human cell polarity protein lethal giant larvae 2.
Proc.Natl.Acad.Sci.USA, 116, 2019
1IDA
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BU of 1ida by Molmil
CRYSTAL STRUCTURES OF HIV-2 PROTEASE IN COMPLEX WITH INHIBITORS CONTAINING THE HYDROXYETHYLAMINE DIPEPTIDE ISOSTERE
分子名称: N-[(1R)-1-{[(1S,2S)-1-benzyl-3-{(2R,4S)-2-(tert-butylcarbamoyl)-4-[(pyridin-3-ylmethyl)sulfanyl]piperidin-1-yl}-2-hydroxypropyl]carbamoyl}-2-methylpropyl]quinoline-2-carboxamide, Protease
著者Tong, L, Anderson, P.C.
登録日1994-10-19
公開日1995-01-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of HIV-2 protease in complex with inhibitors containing the hydroxyethylamine dipeptide isostere.
Structure, 3, 1995
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
分子名称: Bromodomain-containing protein 4, FOXO3a peptide
著者Zeng, L, Zhou, M.-M.
登録日2018-10-02
公開日2018-10-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
6NPL
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BU of 6npl by Molmil
Cryo-EM structure of NKCC1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
著者Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
登録日2019-01-17
公開日2019-07-31
最終更新日2019-08-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
1I5N
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BU of 1i5n by Molmil
Crystal structure of the P1 domain of CheA from Salmonella typhimurium
分子名称: CHEMOTAXIS PROTEIN CHEA, SULFATE ION
著者Mourey, L, Da Re, S, Pedelacq, J.-D, Tolstyk, T, Faurie, C, Guillet, V, Stock, J.B, Samama, J.-P.
登録日2001-02-28
公開日2001-07-11
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of the CheA histidine phosphotransfer domain that mediates response regulator phosphorylation in bacterial chemotaxis
J.Biol.Chem., 276, 2001
1I7E
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BU of 1i7e by Molmil
C-Terminal Domain Of Mouse Brain Tubby Protein bound to Phosphatidylinositol 4,5-bis-phosphate
分子名称: L-ALPHA-GLYCEROPHOSPHO-D-MYO-INOSITOL-4,5-BIS-PHOSPHATE, TUBBY PROTEIN
著者Santagata, S, Boggon, T.J, Baird, C.L, Shan, W.S, Shapiro, L.
登録日2001-03-08
公開日2001-06-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献G-protein signaling through tubby proteins.
Science, 292, 2001
1L2X
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BU of 1l2x by Molmil
Atomic Resolution Crystal Structure of a Viral RNA Pseudoknot
分子名称: MAGNESIUM ION, POTASSIUM ION, RNA pseudoknot, ...
著者Egli, M, Minasov, G, Su, L, Rich, A.
登録日2002-02-25
公開日2002-03-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution.
Proc.Natl.Acad.Sci.USA, 99, 2002
3DP1
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BU of 3dp1 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3n
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
2IAM
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BU of 2iam by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
3DP0
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BU of 3dp0 by Molmil
Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with compound 3m
分子名称: (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, BENZAMIDINE, CHLORIDE ION, ...
著者Zhang, L, He, L, Liu, X, Liu, H, Shen, X, Jiang, H.
登録日2008-07-07
公開日2009-05-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination.
J.Med.Chem., 52, 2009
6NIG
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BU of 6nig by Molmil
Crystal structure of the human TLR2-Diprovocim complex
分子名称: (3S,4S,3'S,4'S)-1,1'-(1,4-phenylenedicarbonyl)bis{N~3~,N~4~-bis[(1S,2R)-2-phenylcyclopropyl]pyrrolidine-3,4-dicarboxami de}, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhang, H, Beutler, B.A, Tomchick, D.R, Su, L.
登録日2018-12-27
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim.
J. Med. Chem., 62, 2019
6NAU
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BU of 6nau by Molmil
1.55 Angstrom Resolution Crystal Structure of 6-phosphogluconolactonase from Klebsiella pneumoniae
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-phosphogluconolactonase, CHLORIDE ION
著者Minasov, G, Shuvalova, L, Pshenychnyi, S, Dubrovska, I, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-12-06
公開日2018-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae.
Microbiol Resour Announc, 12, 2023
6NBU
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BU of 6nbu by Molmil
CRISPR Complex Subunit Csm2 from Staphylococcus epidermidis RP62a
分子名称: CRISPR-associated protein
著者Dorsey, B.W, Huang, L, Mondragon, A.
登録日2018-12-10
公開日2019-02-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural organization of a Type III-A CRISPR effector subcomplex determined by X-ray crystallography and cryo-EM.
Nucleic Acids Res., 47, 2019
6O2R
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BU of 6o2r by Molmil
Deacetylated Microtubules
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E.
登録日2019-02-24
公開日2019-05-22
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Effects of alpha-tubulin acetylation on microtubule structure and stability.
Proc.Natl.Acad.Sci.USA, 116, 2019
3FXT
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BU of 3fxt by Molmil
Crystal structure of the N-terminal domain of human NUDT6
分子名称: GLYCEROL, Nucleoside diphosphate-linked moiety X motif 6
著者Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Siponen, M.I, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Wikstrom, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2009-01-21
公開日2009-03-03
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the N-terminal domain of human NUDT6
To be Published
6NXV
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BU of 6nxv by Molmil
Crystal structure of the theta class glutathione S-transferase from the citrus canker pathogen Xanthomonas axonopodis pv. citri, apo form
分子名称: CHLORIDE ION, DIMETHYL SULFOXIDE, Glutathione S-transferase
著者Hilario, E, De Keyser, S, Fan, L.
登録日2019-02-10
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and biochemical characterization of a glutathione transferase from the citrus canker pathogen Xanthomonas.
Acta Crystallogr D Struct Biol, 76, 2020
6O15
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BU of 6o15 by Molmil
Crystal structure of a putative oxidoreductase YjhC from Escherichia coli in complex with NAD(H)
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, Uncharacterized oxidoreductase YjhC
著者Horne, C.R, Kind, L, Davies, J.S, Dobson, R.C.
登録日2019-02-17
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.
Proteins, 88, 2020
3G1U
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BU of 3g1u by Molmil
Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Siponen, M.I, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Wisniewska, M, Schueler, H, Structural Genomics Consortium (SGC)
登録日2009-01-30
公開日2009-02-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Leishmania major S-adenosylhomocysteine hydrolase
To be Published

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