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1RJ7
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Crystal structure of EDA-A1
分子名称: Ectodysplasin A
著者Hymowitz, S.G, Compaan, D.M, Yan, M, Ackerly, H, Dixit, V.M, Starovasnik, M.A, de Vos, A.M.
登録日2003-11-18
公開日2003-12-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Structure, 11, 2003
1IMX
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1.8 Angstrom crystal structure of IGF-1
分子名称: BROMIDE ION, Insulin-like Growth Factor 1A, N,N-BIS(3-D-GLUCONAMIDOPROPYL)DEOXYCHOLAMIDE
著者Vajdos, F.F, Ultsch, M, Schaffer, M.L, Deshayes, K.D, Liu, J, Skelton, N.J, de Vos, A.M.
登録日2001-05-11
公開日2001-09-05
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal structure of human insulin-like growth factor-1: detergent binding inhibits binding protein interactions.
Biochemistry, 40, 2001
1A21
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TISSUE FACTOR (TF) FROM RABBIT
分子名称: TISSUE FACTOR
著者Muller, Y.A, De Vos, A.M.
登録日1998-01-14
公開日1998-05-27
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Hinge bending within the cytokine receptor superfamily revealed by the 2.4 A crystal structure of the extracellular domain of rabbit tissue factor.
Protein Sci., 7, 1998
1D0G
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BU of 1d0g by Molmil
CRYSTAL STRUCTURE OF DEATH RECEPTOR 5 (DR5) BOUND TO APO2L/TRAIL
分子名称: APOPTOSIS-2 LIGAND, CHLORIDE ION, DEATH RECEPTOR-5, ...
著者Hymowitz, S.G, Christinger, H.W, Fuh, G, O'Connell, M.P, Kelley, R.F, Ashkenazi, A, de Vos, A.M.
登録日1999-09-09
公開日1999-10-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5.
Mol.Cell, 4, 1999
1HUW
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BU of 1huw by Molmil
THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION
分子名称: HUMAN GROWTH HORMONE
著者Ultsch, M.H, Somers, W.S, Kossiakoff, A.A, De Vos, A.M.
登録日1993-09-22
公開日1994-01-31
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of affinity-matured human growth hormone at 2 A resolution.
J.Mol.Biol., 236, 1994
1JPY
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BU of 1jpy by Molmil
Crystal structure of IL-17F
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hymowitz, S.G, Filvaroff, E.H, Yin, J, Lee, J, Cai, L, Risser, P, Maruoka, M, Mao, W, Foster, J, Kelley, R, Pan, G, Gurney, A.L, de Vos, A.M, Starovasnik, M.A.
登録日2001-08-03
公開日2001-09-28
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20, 2001
1DN2
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FC FRAGMENT OF HUMAN IGG1 IN COMPLEX WITH AN ENGINEERED 13 RESIDUE PEPTIDE DCAWHLGELVWCT-NH2
分子名称: ENGINEERED PEPTIDE, IMMUNOGLOBULIN LAMBDA HEAVY CHAIN, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者DeLano, W.L, Ultsch, M.H, de Vos, A.M, Wells, J.A.
登録日1999-12-15
公開日2000-05-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Convergent solutions to binding at a protein-protein interface.
Science, 287, 2000
1FLT
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BU of 1flt by Molmil
VEGF IN COMPLEX WITH DOMAIN 2 OF THE FLT-1 RECEPTOR
分子名称: FMS-LIKE TYROSINE KINASE 1, VASCULAR ENDOTHELIAL GROWTH FACTOR
著者Wiesmann, C, De Vos, A.M.
登録日1997-11-20
公開日1999-01-13
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor.
Cell(Cambridge,Mass.), 91, 1997
1BHT
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BU of 1bht by Molmil
NK1 FRAGMENT OF HUMAN HEPATOCYTE GROWTH FACTOR
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEPATOCYTE GROWTH FACTOR, SULFATE ION
著者Ultsch, M.H, Lokker, N.A, Godowski, P.J, De Vos, A.M.
登録日1998-06-10
公開日1998-11-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the NK1 fragment of human hepatocyte growth factor at 2.0 A resolution.
Structure, 6, 1998
1BJ1
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VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY
分子名称: Fab fragment, heavy chain, light chain, ...
著者Muller, Y.A, Christinger, H.W, De Vos, A.M.
登録日1998-06-30
公開日1999-01-13
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.
Structure, 6, 1998
1BP3
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THE XRAY STRUCTURE OF A GROWTH HORMONE-PROLACTIN RECEPTOR COMPLEX
分子名称: PROTEIN (GROWTH HORMONE), PROTEIN (PROLACTIN RECEPTOR), ZINC ION
著者Somers, W, Ultsch, M, De Vos, A.M, Kossiakoff, A.A.
登録日1998-08-12
公開日1998-08-19
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The X-ray structure of a growth hormone-prolactin receptor complex.
Nature, 372, 1994
1DG6
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BU of 1dg6 by Molmil
CRYSTAL STRUCTURE OF APO2L/TRAIL
分子名称: APO2L/TNF-RELATED APOPOTIS INDUCING LIGAND (TRAIL), CHLORIDE ION, ZINC ION
著者Hymowitz, S.G, O'ConnelL, M.P, Ultsch, M.H, de Vos, A.M, Kelley, R.F.
登録日1999-11-23
公開日2000-01-26
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献A unique zinc-binding site revealed by a high-resolution X-ray structure of homotrimeric Apo2L/TRAIL.
Biochemistry, 39, 2000
1KF9
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BU of 1kf9 by Molmil
PHAGE DISPLAY DERIVED VARIANT OF HUMAN GROWTH HORMONE COMPLEXED WITH TWO COPIES OF THE EXTRACELLULAR DOMAIN OF ITS RECEPTOR
分子名称: EXTRACELLULAR DOMAIN HUMAN GROWTH HORMONE RECEPTOR (1-238), PHAGE DISPLAY DERIVED VARIANT HUMAN GROWTH HORMONE
著者Schiffer, C.A, Ultsch, M, Walsh, S, Somers, W, De Vos, A.M, Kossiakoff, A.A.
登録日2001-11-19
公開日2002-11-20
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of a Phage Display Derived Variant of Human Growth Hormone Complexed to Two Copies of the Extracellular Domain of its Receptor: Evidence for Strong Structural Coupling between Receptor Binding Sites
J.Mol.Biol., 316, 2002
2Q21
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BU of 2q21 by Molmil
CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
分子名称: C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kim, S.-H.
登録日1991-09-25
公開日1992-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
J.Mol.Biol., 217, 1991
1Q21
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CRYSTAL STRUCTURES AT 2.2 ANGSTROMS RESOLUTION OF THE CATALYTIC DOMAINS OF NORMAL RAS PROTEIN AND AN ONCOGENIC MUTANT COMPLEXED WITH GSP
分子名称: C-H-RAS P21 PROTEIN CATALYTIC DOMAIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Kim, S.-H.
登録日1991-09-25
公開日1992-07-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures at 2.2 A resolution of the catalytic domains of normal ras protein and an oncogenic mutant complexed with GDP.
J.Mol.Biol., 217, 1991
1HE7
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Human Nerve growth factor receptor TrkA
分子名称: GLYCEROL, HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR
著者Banfield, M, Robertson, A, Allen, S, Dando, J, Tyler, S, Bennett, G, Brain, S, Mason, G, Holden, P, Clarke, A, Naylor, R, Wilcock, G, Brady, R, Dawbarn, D.
登録日2000-11-20
公開日2001-04-02
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification and Structure of the Nerve Growth Factor Binding Site on Trka.
Biochem.Biophys.Res.Commun., 282, 2001
1PMK
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KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES
分子名称: PLASMINOGEN KRINGLE 4
著者Padmanabhan, K, Tulinsky, A.
登録日1994-04-25
公開日1994-06-22
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Kringle-kringle interactions in multimer kringle structures.
Protein Sci., 3, 1994
1PML
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KRINGLE-KRINGLE INTERACTIONS IN MULTIMER KRINGLE STRUCTURES
分子名称: CHLORIDE ION, TISSUE PLASMINOGEN ACTIVATOR KRINGLE 2
著者Padmanabhan, K, Tulinsky, A.
登録日1994-04-25
公開日1994-06-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Kringle-kringle interactions in multimer kringle structures.
Protein Sci., 3, 1994
4BLB
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BU of 4blb by Molmil
Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, ZINC FINGER PROTEIN GLI1, ...
著者Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
4BLD
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Crystal structure of a human Suppressor of fused (SUFU)-GLI3p complex
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, TRANSCRIPTIONAL ACTIVATOR GLI3, ...
著者Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
4BL9
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Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I)
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Cherry, A.L, Finta, C, Karlstrom, M, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
4BL8
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Crystal structure of full-length human Suppressor of fused (SUFU)
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Karlstrom, M, Finta, C, Cherry, A.L, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
4BLA
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BU of 4bla by Molmil
Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form II)
分子名称: MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG
著者Cherry, A.L, Finta, C, Karlstrom, M, Toftgard, R, Jovine, L.
登録日2013-05-02
公開日2013-11-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
Acta Crystallogr.,Sect.D, 69, 2013
2SPT
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BU of 2spt by Molmil
DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTHROMBIN, STRONTIUM ION
著者Tulinsky, A.
登録日1994-02-01
公開日1994-05-31
最終更新日2025-03-26
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1.
Biochemistry, 33, 1994
1JPS
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Crystal structure of tissue factor in complex with humanized Fab D3h44
分子名称: immunoglobulin Fab D3H44, heavy chain, light chain, ...
著者Faelber, K, Kirchhofer, D, Presta, L, Kelley, R.F, Muller, Y.A.
登録日2001-08-03
公開日2002-02-03
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The 1.85 A resolution crystal structures of tissue factor in complex with humanized Fab D3h44 and of free humanized Fab D3h44: revisiting the solvation of antigen combining sites.
J.Mol.Biol., 313, 2001
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