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6DNQ
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BU of 6dnq by Molmil
HBZ77 in complex with KIX and c-Myb
分子名称: 1,2-ETHANEDIOL, BZIP factor, CREB-binding protein, ...
著者Yang, K, Wright, P.E, Stanfield, R.L.
登録日2018-06-07
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3BF3
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BU of 3bf3 by Molmil
Type III pantothenate kinase from Thermotoga maritima complexed with product phosphopantothenate
分子名称: MAGNESIUM ION, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, Type III pantothenate kinase
著者Yang, K, Huerta, C, Strauss, E, Zhang, H.
登録日2007-11-20
公開日2008-06-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase.
Biochemistry, 47, 2008
3BEX
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BU of 3bex by Molmil
Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate
分子名称: PANTOTHENOIC ACID, PHOSPHATE ION, Type III pantothenate kinase
著者Yang, K, Huerta, C, Strauss, E, Zhang, H.
登録日2007-11-20
公開日2008-06-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase.
Biochemistry, 47, 2008
3E66
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BU of 3e66 by Molmil
Crystal structure of the beta-finger domain of yeast Prp8
分子名称: PRP8
著者Yang, K, Zhang, L, Xu, T, Heroux, A, Zhao, R.
登録日2008-08-14
公開日2008-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of the beta-finger domain of Prp8 reveals analogy to ribosomal proteins.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3BF1
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BU of 3bf1 by Molmil
Type III pantothenate kinase from Thermotoga maritima complexed with pantothenate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, PANTOTHENOIC ACID, Type III pantothenate kinase
著者Yang, K, Huerta, C, Strauss, E, Zhang, H.
登録日2007-11-20
公開日2008-06-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for substrate binding and the catalytic mechanism of type III pantothenate kinase.
Biochemistry, 47, 2008
7JP0
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BU of 7jp0 by Molmil
Crystal structure of Mpro with inhibitor r1
分子名称: 3C-like proteinase, DIMETHYL SULFOXIDE, N-[(benzyloxy)carbonyl]-L-valyl-N-{(2R)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide
著者Yang, K, Liu, W.
登録日2020-08-07
公開日2021-10-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of Mpro with inhibitor r1
To Be Published
7TIK
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BU of 7tik by Molmil
Structure of the SARS-CoV-2 Omicron spike post-fusion bundle
分子名称: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2'
著者Yang, K, Brunger, A.T.
登録日2022-01-13
公開日2022-04-06
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
1P8X
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BU of 1p8x by Molmil
The Calcium-Activated C-terminal half of gelsolin
分子名称: CALCIUM ION, Gelsolin precursor, plasma
著者Narayan, K, Burtnick, L.D, Robinson, R.C.
登録日2003-05-08
公開日2003-10-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Activation in isolation: Exposure of the actin-binding site in the C-terminal half of gelsolin does not require actin
FEBS LETT., 552, 2003
6KNC
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BU of 6knc by Molmil
PolD-PCNA-DNA (form B)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
6KNB
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BU of 6knb by Molmil
PolD-PCNA-DNA (form A)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
8FA2
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BU of 8fa2 by Molmil
Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex
分子名称: Scaffolded Spike protein S2' HR1, Spike protein S2' 42G
著者Yang, K, Brunger, A.T.
登録日2022-11-25
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.82 Å)
主引用文献Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FA1
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BU of 8fa1 by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation
分子名称: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2
著者Yang, K, Brunger, A.T.
登録日2022-11-25
公開日2023-03-29
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.51 Å)
主引用文献Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
2GTD
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BU of 2gtd by Molmil
Crystal Structure of a Type III Pantothenate Kinase: Insight into the Catalysis of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria
分子名称: Type III Pantothenate Kinase
著者Yang, K, Eyobo, Y, Brand, A.L, Martynowski, D, Tomchick, D.
登録日2006-04-27
公開日2006-08-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of a Type III Pantothenate Kinase: Insight into the Mechanism of an Essential Coenzyme A Biosynthetic Enzyme Universally Distributed in Bacteria.
J.Bacteriol., 188, 2006
5HQP
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BU of 5hqp by Molmil
Crystal structure of the ERp44-peroxiredoxin 4 complex
分子名称: Endoplasmic reticulum resident protein 44, Peroxiredoxin-4
著者Yang, K, Li, D.F, Wang, X, Wang, C.C.
登録日2016-01-22
公開日2016-10-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of the ERp44-Peroxiredoxin 4 Complex Reveals the Molecular Mechanisms of Thiol-Mediated Protein Retention.
Structure, 24, 2016
2A2Y
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BU of 2a2y by Molmil
NMR Structue of Sso10b2 from Sulfolobus solfataricus
分子名称: DNA/RNA-binding protein Alba 2
著者Biyani, K, Kahsai, M.A, Clark, A.T, Armstrong, T.L, Edmondson, S.P, Shriver, J.W.
登録日2005-06-23
公開日2005-11-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure, stability, and nucleic Acid binding of the hyperthermophile protein sso10b2.
Biochemistry, 44, 2005
7P5O
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BU of 7p5o by Molmil
Crystal structure of Aspergillus fumigatus phosphoglucomutase in complex with the reaction intermediate
分子名称: 1,6-di-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, Phosphoglucomutase
著者Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-07-14
公開日2022-07-27
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Targeting an essential step in the biosynthetic pathway of uridine diphosphate glucose in Aspergillus fumigatus
To Be Published
7PPR
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BU of 7ppr by Molmil
The structure of UDP-glucose pyrophosphorylase from Aspergillus fumigatus
分子名称: CHLORIDE ION, SULFATE ION, UTP--glucose-1-phosphate uridylyltransferase
著者Morton, S, Raimi, O.G, Yan, K, van Aalten, D.M.F.
登録日2021-09-14
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Genetic and structural validation of UDP-glucose pyrophosphorylase as a novel antifungal target against Aspergillus fumigatus
To Be Published
7U34
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BU of 7u34 by Molmil
The structure of phosphoglucose isomerase from Aspergillus fumigatus
分子名称: CHLORIDE ION, CITRATE ANION, GLYCEROL, ...
著者Yan, K, Kowalski, B, Fang, W, van Aalten, D.
登録日2022-02-25
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Phosphoglucose Isomerase Is Important for Aspergillus fumigatus Cell Wall Biogenesis.
Mbio, 13, 2022
5JZX
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BU of 5jzx by Molmil
Crystal Structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Mycobacterium tuberculosis
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, UDP-N-acetylenolpyruvoylglucosamine reductase
著者Dharavath, S, Eniyan, K, Bajpai, U, Gourinath, S.
登録日2016-05-17
公開日2017-05-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of UDP-N-acetylglucosamine-enolpyruvate reductase (MurB) from Mycobacterium tuberculosis
Biochim. Biophys. Acta, 1866, 2017
1FUS
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BU of 1fus by Molmil
CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2'GMP
分子名称: RIBONUCLEASE F1
著者Katayanagi, K, Vassylyev, D.G, Ishikawa, K, Morikawa, K.
登録日1993-01-18
公開日1993-10-31
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
J.Mol.Biol., 230, 1993
1FUT
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BU of 1fut by Molmil
CRYSTAL STRUCTURES OF RIBONUCLEASE F1 OF FUSARIUM MONILIFORME IN ITS FREE FORM AND IN COMPLEX WITH 2'GMP
分子名称: GUANOSINE-2'-MONOPHOSPHATE, RIBONUCLEASE F1
著者Katayanagi, K, Vassylyev, D.G, Ishikawa, K, Morikawa, K.
登録日1993-01-18
公開日1993-10-31
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
J.Mol.Biol., 230, 1993
7KK6
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BU of 7kk6 by Molmil
Structure of the catalytic domain of PARP1 in complex with veliparib
分子名称: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Gajiwala, K.S, Ryan, K.
登録日2020-10-27
公開日2021-01-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.
J.Biol.Chem., 296, 2021
7KKQ
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BU of 7kkq by Molmil
Structure of the catalytic domain of tankyrase 1 in complex with veliparib
分子名称: (2R)-2-(7-carbamoyl-1H-benzimidazol-2-yl)-2-methylpyrrolidinium, Poly [ADP-ribose] polymerase, ZINC ION
著者Gajiwala, K.S, Ryan, K.
登録日2020-10-27
公開日2021-01-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.
J.Biol.Chem., 296, 2021
7KK2
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Structure of the catalytic domain of PARP1
分子名称: Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Gajiwala, K.S, Ryan, K.
登録日2020-10-27
公開日2021-01-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.695 Å)
主引用文献Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.
J.Biol.Chem., 296, 2021
7KK5
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BU of 7kk5 by Molmil
Structure of the catalytic domain of PARP1 in complex with niraparib
分子名称: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, Poly [ADP-ribose] polymerase 1, SULFATE ION
著者Gajiwala, K.S, Ryan, K.
登録日2020-10-27
公開日2021-01-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.
J.Biol.Chem., 296, 2021

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