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3L5B
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BU of 3l5b by Molmil
Structure of BACE Bound to SCH713601
分子名称: (2Z,5R)-3-(3-chlorobenzyl)-2-imino-5-methyl-5-(2-methylpropyl)imidazolidin-4-one, Beta-secretase 1, D(-)-TARTARIC ACID
著者Strickland, C, Zhu, Z.
登録日2009-12-21
公開日2010-02-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Discovery of Cyclic Acylguanidines as Highly Potent and Selective beta-Site Amyloid Cleaving Enzyme (BACE) Inhibitors: Part I-Inhibitor Design and Validation
J.Med.Chem., 53, 2010
2JXB
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BU of 2jxb by Molmil
Structure of CD3epsilon-Nck2 first SH3 domain complex
分子名称: T-cell surface glycoprotein CD3 epsilon chain, Cytoplasmic protein NCK2
著者Takeuchi, K, Yang, H, Ng, E, Park, S, Sun, Z.J, Reinherz, E.L, Wagner, G.
登録日2007-11-09
公開日2008-09-23
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and functional evidence that Nck interaction with CD3epsilon regulates T-cell receptor activity.
J.Mol.Biol., 380, 2008
2JWO
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BU of 2jwo by Molmil
A PHD finger motif in the C-terminus of RAG2 modulates recombination activity
分子名称: V(D)J recombination-activating protein 2, ZINC ION
著者Ivanov, D, Hyberts, S.G, Sun, Z, Wagner, G.
登録日2007-10-17
公開日2007-11-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
J.Biol.Chem., 280, 2005
2KY6
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BU of 2ky6 by Molmil
Structure of ARC92VBD/MED25ACID
分子名称: Mediator of RNA polymerase II transcription subunit 25
著者Milbradt, A.G, Sun, Z.J, Selenko, P, Takeuchi, K, Naar, A.M, Wagner, G.
登録日2010-05-14
公開日2011-03-09
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the VP16 transactivator target in the Mediator.
Nat.Struct.Mol.Biol., 18, 2011
5WUU
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BU of 5wuu by Molmil
Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring
分子名称: Bromodomain-containing protein 4, ~{N}-methyl-~{N}-[3-[(2-oxidanylidenechromen-4-yl)amino]propyl]thiophene-2-carboxamide
著者Zhang, H, Sun, Z.Y.
登録日2016-12-21
公開日2017-04-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.724 Å)
主引用文献Discovery of novel BRD4 inhibitors by high-throughput screening, crystallography, and cell-based assays.
Bioorg. Med. Chem. Lett., 27, 2017
8XKE
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BU of 8xke by Molmil
The structure of HLA-A/14-3-D
分子名称: Beta-2-microglobulin, GLU-VAL-ASP-ASN-ALA-THR-ARG-PHE-ALA-SER-VAL-TYR, HLA class I heavy chain
著者Zhang, J.N, Yue, C, Liu, J, Sun, Z.Y.
登録日2023-12-23
公開日2024-07-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.
Immunohorizons, 8, 2024
7EDO
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BU of 7edo by Molmil
First insight into marsupial MHC I peptide presentation: immune features of lower mammals paralleled with bats
分子名称: Beta-2-microglobulin, CYS-ASN-VAL-THR-LEU-ASN-TYR-PRO, MHC class I antigen
著者Wang, P.Y, Yue, C, Lu, D, Liu, K.F, Liu, S, Yao, S.J, Chai, Y, Qi, J.X, Lou, Y.L, Sun, Z.Y, Gao, G.F, Liu, W.J.
登録日2021-03-16
公開日2021-08-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Peptide Presentations of Marsupial MHC Class I Visualize Immune Features of Lower Mammals Paralleled with Bats.
J Immunol., 207, 2021
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