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6LVB
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BU of 6lvb by Molmil
Structure of Dimethylformamidase, tetramer
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R.
登録日2020-02-02
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
7VNS
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BU of 7vns by Molmil
Sandercyanin mutant E79A-Biliverdin complex
分子名称: BILIVERDINE IX ALPHA, Sandercyanin Fluorescent Protein
著者Yadav, K, Ghosh, S, Subramanian, R.
登録日2021-10-12
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Phenylalanine stacking enhances the red fluorescence of biliverdin IX alpha on UV excitation in sandercyanin fluorescent protein.
Febs Lett., 596, 2022
7VNL
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BU of 7vnl by Molmil
Sandercyanin mutant-F55A-Biliverdin complex
分子名称: BILIVERDINE IX ALPHA, Sandercyanin Fluorescent Protein, TETRAETHYLENE GLYCOL
著者Yadav, K, Ghosh, S, Subramanian, R.
登録日2021-10-11
公開日2022-05-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Phenylalanine stacking enhances the red fluorescence of biliverdin IX alpha on UV excitation in sandercyanin fluorescent protein.
Febs Lett., 596, 2022
7W8J
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BU of 7w8j by Molmil
Dimethylformamidase, 2x(A2B2)
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Vinothkumar, K.R, Subramanian, R, Arya, C, Ramanathan, G.
登録日2021-12-07
公開日2022-04-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Dimethylformamidase with a Unique Iron Center
To Be Published
6LVC
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BU of 6lvc by Molmil
Structure of Dimethylformamidase, dimer
分子名称: FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R.
登録日2020-02-02
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
6LVD
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BU of 6lvd by Molmil
Structure of Dimethylformamidase, tetramer, Y440A mutant
分子名称: N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit
著者Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R.
登録日2020-02-02
公開日2020-06-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
6MLR
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BU of 6mlr by Molmil
Cryo-EM structure of microtubule-bound Kif7 in the AMPPNP state
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF7, ...
著者Mani, N, Jiang, S, Wilson-Kubalek, E.M, Ku, P, Milligan, R.A, Subramanian, R.
登録日2018-09-27
公開日2019-05-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7.
Dev.Cell, 49, 2019
6MLQ
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BU of 6mlq by Molmil
Cryo-EM structure of microtubule-bound Kif7 in the ADP state
分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Mani, N, Jiang, S, Wilson-Kubalek, E.M, Ku, P, Milligan, R.A, Subramanian, R.
登録日2018-09-27
公開日2019-05-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7.
Dev.Cell, 49, 2019
7O3K
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BU of 7o3k by Molmil
Structure of a monomeric variant (L135E) of Sandercyanin fluorescent protein bound to biliverdin IX-alpha
分子名称: BILIVERDINE IX ALPHA, Sandercyanin Fluorescent Protein
著者Ghosh, S, Yadav, K, Ramaswamy, S.
登録日2021-04-01
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Modulation of biliverdin dynamics and spectral properties by Sandercyanin.
Rsc Adv, 12, 2022
7Q02
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BU of 7q02 by Molmil
Zn-free structure of lipocalin-like Milk protein, inspired from Diploptera punctata, expressed in Saccharomyces cerevisiae
分子名称: Milk protein, PALMITOLEIC ACID
著者Banerjee, S, Dhanabalan, K.V, Ramaswamy, S.
登録日2021-10-14
公開日2021-12-22
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structure of recombinantly expressed cockroach Lili-Mip protein in glycosylated and deglycosylated forms.
Biochim Biophys Acta Gen Subj, 1866, 2022
7D75
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BU of 7d75 by Molmil
X-ray structure of a domain-swapped dimer of Monellin with YEDKG loop-1 mutant
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ...
著者Manjula, R, Ramaswamy, S, Gosavi, S.
登録日2020-10-03
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Domain swapped structure of Monellin Loop1-mutant
To Be Published
8THI
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BU of 8thi by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (parallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, SODIUM ION, Sialic acid TRAP transporter permease protein SiaT
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
8THJ
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BU of 8thj by Molmil
Cryo-EM structure of the Tripartite ATP-independent Periplasmic (TRAP) transporter SiaQM from Haemophilus influenzae (antiparallel dimer)
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, PHOSPHATIDYLETHANOLAMINE, SODIUM ION, ...
著者Davies, J.S, Currie, M.C, Dobson, R.C.J, North, R.A.
登録日2023-07-16
公開日2023-11-22
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.99 Å)
主引用文献Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.
Elife, 12, 2024
4F1S
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BU of 4f1s by Molmil
Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine-sulfonamide inhibitor
分子名称: N-(5-{[3-(4-amino-6-methyl-1,3,5-triazin-2-yl)-5-(tetrahydro-2H-pyran-4-yl)pyridin-2-yl]amino}-2-chloropyridin-3-yl)methanesulfonamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Whittington, D.A, Tang, J, Yakowec, P.
登録日2012-05-07
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold.
Bioorg.Med.Chem.Lett., 22, 2012
4FLH
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BU of 4flh by Molmil
Crystal structure of human PI3K-gamma in complex with AMG511
分子名称: 4-(2-[(5-fluoro-6-methoxypyridin-3-yl)amino]-5-{(1R)-1-[4-(methylsulfonyl)piperazin-1-yl]ethyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION
著者Whittington, D.A, Tang, J, Yakowec, P.
登録日2012-06-14
公開日2012-08-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511.
J.Med.Chem., 55, 2012
6XT2
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BU of 6xt2 by Molmil
EQADH-NADH-HEPTAFLUOROBUTANOL, P21
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2,2,3,3,4,4,4-heptafluorobutan-1-ol, ...
著者Plapp, B.V, Ramaswamy, S.
登録日2020-07-16
公開日2020-08-05
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Alternative binding modes in abortive NADH-alcohol complexes of horse liver alcohol dehydrogenase.
Arch.Biochem.Biophys., 701, 2021
7O2Y
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BU of 7o2y by Molmil
Sandercyanin Fluorescent Protein variant V71E bound to biliverdin IX-alpha
分子名称: BILIVERDINE IX ALPHA, Sandercyanin Fluorescent Protein
著者Ghosh, S, Yadav, K, Ramaswamy, S.
登録日2021-03-31
公開日2022-04-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Modulation of biliverdin dynamics and spectral properties by Sandercyanin.
Rsc Adv, 12, 2022
6VVA
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BU of 6vva by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300)
分子名称: CHLORIDE ION, CITRIC ACID, N-acetylmannosamine-6-phosphate 2-epimerase
著者Renwick, R.C.J, Currie, M.J.
登録日2020-02-17
公開日2021-02-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
6LVV
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BU of 6lvv by Molmil
N, N-dimethylformamidase
分子名称: 1,2-ETHANEDIOL, FE (III) ION, N,N-dimethylformamidase large subunit, ...
著者Arya, C.K, Ramaswamy, S, Kutti, R.V, Gurunath, R.
登録日2020-02-05
公開日2020-08-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.
Angew.Chem.Int.Ed.Engl., 59, 2020
7MFN
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BU of 7mfn by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase E180A from Staphylococcus aureus (strain MRSA USA300)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ...
著者Currie, M.J, Dobson, R.C.J.
登録日2021-04-10
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
7MFS
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BU of 7mfs by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300) with substrate and product bound
分子名称: CHLORIDE ION, N-acetyl-D-glucosamine-6-phosphate, N-acetylmannosamine-6-phosphate, ...
著者Currie, M.J, Dobson, R.C.J.
登録日2021-04-11
公開日2022-04-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
7MQT
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BU of 7mqt by Molmil
N-Acetylmannosamine-6-phosphate 2-epimerase from Staphylococcus aureus (strain MRSA USA300) with 5-deoxy substrate bound
分子名称: 2-acetamido-2,5-dideoxy-6-O-phosphono-D-lyxo-hexose, CHLORIDE ION, CITRIC ACID, ...
著者Currie, M.J, Dobson, R.C.J.
登録日2021-05-06
公開日2022-04-20
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献N-acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization.
J.Biol.Chem., 297, 2021
5KJ1
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BU of 5kj1 by Molmil
G173A horse liver alcohol dehydrogenase complexed with NAD+ and pentafluorobenzyl alcohol
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 2,3,4,5,6-PENTAFLUOROBENZYL ALCOHOL, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V.
登録日2016-06-17
公開日2016-07-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Dependence of crystallographic atomic displacement parameters on temperature (25-150 K) for complexes of horse liver alcohol dehydrogenase.
Acta Crystallogr D Struct Biol, 78, 2022
5ZJP
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Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae with N-acetylglucosamine-6-phosphate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-acetyl-D-glucosamine-6-phosphate, ...
著者Manjunath, L, Guntupalli, S.R.
登録日2018-03-21
公開日2018-12-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae
Acta Crystallogr F Struct Biol Commun, 74, 2018
5ZJN
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Structure of N-acetylmannosamine-6-phosphate-2-epimerase from Vibrio cholerae with N-acetylmannosamine-6-phosphate
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-acetylmannosamine-6-phosphate, ...
著者Manjunath, L, Guntupalli, S.
登録日2018-03-21
公開日2018-09-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Crystal structures and kinetic analyses of N-acetylmannosamine-6-phosphate 2-epimerases from Fusobacterium nucleatum and Vibrio cholerae
Acta Crystallogr F Struct Biol Commun, 74, 2018

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