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2B8Z
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BU of 2b8z by Molmil
Crystal structure of the interleukin-4 variant R85A
分子名称: Interleukin-4, SULFATE ION
著者Kraich, M, Klein, M, Patino, E, Harrer, H, Sebald, W, Mueller, T.D.
登録日2005-10-10
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A modular interface of IL-4 allows for scalable affinity without affecting specificity for the IL-4 receptor
Bmc Biol., 4, 2006
3EVS
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BU of 3evs by Molmil
Crystal structure of the GDF-5:BMP receptor IB complex.
分子名称: Bone morphogenetic protein receptor type-1B, Growth/differentiation factor 5
著者Kotzsch, A, Mueller, T.D.
登録日2008-10-13
公開日2009-03-10
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure analysis reveals a spring-loaded latch as molecular mechanism for GDF-5-type I receptor specificity.
Embo J., 28, 2009
1HZI
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BU of 1hzi by Molmil
INTERLEUKIN-4 MUTANT E9A
分子名称: INTERLEUKIN-4, SULFATE ION
著者Hulsmeyer, M, Scheufler, C, Dreyer, M.K.
登録日2001-01-25
公開日2001-08-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation.
Acta Crystallogr.,Sect.D, 57, 2001
6H41
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BU of 6h41 by Molmil
Structure of the complex of the IL-5 inhibitory peptide AF17121 bound to the IL-5 receptor IL-5Ralpha
分子名称: Interleukin-5 receptor subunit alpha, VAL-ASP-GLU-CYS-TRP-ARG-ILE-ILE-ALA-SER-HIS-THR-TRP-PHE-CYS-ALA-GLU-GLU
著者Mueller, T.D, Scheide, J.P.
登録日2018-07-20
公開日2018-12-26
最終更新日2019-02-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural Basis of Interleukin-5 Inhibition by the Small Cyclic Peptide AF17121.
J. Mol. Biol., 431, 2019
2K3G
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BU of 2k3g by Molmil
NMR structure analysis of a BMP receptor
分子名称: Bone morphogenetic protein receptor type-1A
著者Klages, J, Kotzsch, A, Mueller, T, Kessler, H.
登録日2008-05-07
公開日2008-12-16
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The solution structure of BMPR-IA reveals a local disorder-to-order transition upon BMP-2 binding.
Biochemistry, 47, 2008
3B5K
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BU of 3b5k by Molmil
Crystal structure of murine interleukin-5
分子名称: Interleukin-5
著者Mueller, T.D, Patino, E.
登録日2007-10-26
公開日2008-11-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of murine interleukin-5
To be Published
2H62
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BU of 2h62 by Molmil
Crystal structure of a ternary ligand-receptor complex of BMP-2
分子名称: Acvr2b protein, Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Mueller, T.D.
登録日2006-05-30
公開日2007-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor.
Bmc Struct.Biol., 7, 2007
2QJA
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BU of 2qja by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B12
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJB
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BU of 2qjb by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant IA/IB
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA, CHLORIDE ION
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
2QJ9
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BU of 2qj9 by Molmil
Crystal structure analysis of BMP-2 in complex with BMPR-IA variant B1
分子名称: Bone morphogenetic protein 2, Bone morphogenetic protein receptor type IA
著者Kotzsch, A, Mueller, T.D.
登録日2007-07-06
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Structure analysis of bone morphogenetic protein-2 type I receptor complexes reveals a mechanism of receptor inactivation in juvenile polyposis syndrome.
J.Biol.Chem., 283, 2008
1HIJ
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BU of 1hij by Molmil
INTERLEUKIN-4 MUTANT WITH ARG 88 REPLACED WITH GLN (R88Q)
分子名称: INTERLEUKIN-4
著者Mueller, T, Buehner, M.
登録日1995-06-01
公開日1996-01-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
1HIK
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BU of 1hik by Molmil
INTERLEUKIN-4 (WILD-TYPE)
分子名称: INTERLEUKIN-4
著者Mueller, T, Buehner, M.
登録日1995-06-01
公開日1996-01-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models.
J.Mol.Biol., 247, 1995
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