4PER
 
 | | Structure of Gallus gallus ribonuclease inhibitor complexed with Gallus gallus ribonuclease I | | 分子名称: | Angiogenin, Ribonuclease Inhibitor | | 著者 | Bianchetti, C.M, Lomax, J.E, Raines, R.T, Fox, B.G. | | 登録日 | 2014-04-24 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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4ISJ
 | | RNA Ligase RtcB in complex with Mn(II) | | 分子名称: | MANGANESE (II) ION, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | | 著者 | Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. | | 登録日 | 2013-01-16 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.344 Å) | | 主引用文献 | Structures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine Guanylylation.
Biochemistry, 52, 2013
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4IT0
 | | Structure of the RNA ligase RtcB-GMP/Mn(II) complex | | 分子名称: | GUANOSINE-5'-MONOPHOSPHATE, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Desai, K.K, Bingman, C.A, Phillips Jr, G.N, Raines, R.T. | | 登録日 | 2013-01-17 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine Guanylylation.
Biochemistry, 52, 2013
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2GMK
 | | Crystal structure of onconase double mutant with spontaneously-assembled (AMP) 4 stack | | 分子名称: | ADENOSINE MONOPHOSPHATE, P-30 protein | | 著者 | Bae, E, Lee, J.E, Raines, R.T, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2006-04-06 | | 公開日 | 2006-04-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis for catalysis by onconase.
J.Mol.Biol., 375, 2008
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3TSR
 | | X-ray structure of mouse ribonuclease inhibitor complexed with mouse ribonuclease 1 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Ribonuclease inhibitor, ... | | 著者 | Chang, A, Lomax, J.E, Bingman, C.A, Raines, R.T, Phillips Jr, G.N. | | 登録日 | 2011-09-13 | | 公開日 | 2012-09-19 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.1999 Å) | | 主引用文献 | Functional evolution of ribonuclease inhibitor: insights from birds and reptiles.
J.Mol.Biol., 426, 2014
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2XOG
 | | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A | | 分子名称: | (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC | | 著者 | Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R. | | 登録日 | 2010-08-16 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
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2XOI
 | | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A | | 分子名称: | (2S,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-N-[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-4-HYDROXY-2-(HYDROXYMETHYL)OXOLAN-3-YL]METHYLSULFONYL]-3,4-DIHYDROXY-OXOLANE-2-CARBOXAMIDE, RIBONUCLEASE PANCREATIC | | 著者 | Thiyagarajan, N, Smith, B.D, Raines, R.T, Acharya, K.R. | | 登録日 | 2010-08-17 | | 公開日 | 2011-01-19 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Functional and Structural Analyses of N-Acylsulfonamide-Linked Dinucleoside Inhibitors of Ribonuclease A.
FEBS J., 278, 2011
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1TXX
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5U4A
 | | Wild-type Transthyretin in complex with 5-[(1E)-2-(2-Chloro-4-boronic acid)ethenyl]-1,3-benzenediol | | 分子名称: | Transthyretin, {3-chloro-4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl}boronic acid | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4G
 | | Wild-type Transthyretin in complex with 2-Boronic Acid-1-[(1E)-2-(3-boronic acid)ethenyl]-4-chlorobenzene | | 分子名称: | (3-{(E)-2-[2-chloro-4-(hydroxyboranyl)phenyl]ethenyl}phenyl)boronic acid, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U48
 | | Wild-type Transthyretin in complex with 5-[(1E)-2-(4-Boronic acid)ethenyl]-1,3-benzenediol | | 分子名称: | Transthyretin, {4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]phenyl}boronic acid | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4F
 | | Wild-type Transthyretin in complex with 1,1'-(1E)-(1,2-Ethenediyl)bis[2-chloro-4-boronic acid]benzene | | 分子名称: | Transthyretin, [(E)-ethene-1,2-diylbis(3-chloro-4,1-phenylene)]diboronic acid | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U49
 | | Wild-type Transthyretin in complex with 5-[(1E)-2-(2-Chloro-4-hydroxyphenyl)ethenyl]-1,3-benzenediol | | 分子名称: | 5-[(E)-2-(2-chloro-4-hydroxyphenyl)ethenyl]benzene-1,3-diol, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4E
 | | Wild-type Transthyretin in complex with 3-[(1E)-2-(2-Chloro-4-boronic acid)ethenyl]benzoic Acid | | 分子名称: | 3-[(E)-2-(4-borono-2-chlorophenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4D
 | | Wild-type Transthyretin in complex with 3-[(1E)-2-(2-Chloro-4-hydroxyphenyl)ethenyl]benzoic Acid | | 分子名称: | 3-[(E)-2-(2-chloro-4-hydroxyphenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4C
 | | Wild-type Transthyretin in complex with 3-[(1E)-2-(4-Boronic acid)ethenyl]benzoic Acid | | 分子名称: | 3-[(E)-2-(4-boronophenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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5U4B
 | | Wild-type Transthyretin in complex with 3-[(1E)-2-(4-Hydroxyphenyl)ethenyl]benzoic Acid | | 分子名称: | 3-[(E)-2-(4-hydroxyphenyl)ethenyl]benzoic acid, Transthyretin | | 著者 | Windsor, I.W, Smith, T.P, Raines, R.T, Forest, K.T. | | 登録日 | 2016-12-03 | | 公開日 | 2017-09-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.448 Å) | | 主引用文献 | Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation.
J. Med. Chem., 60, 2017
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1W4P
 | | Binding of Nonnatural 3'-Nucleotides to Ribonuclease A | | 分子名称: | 2'-DEOXYURIDINE 3'-MONOPHOSPHATE, PANCREATIC RIBONUCLEASE A | | 著者 | Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T. | | 登録日 | 2004-07-27 | | 公開日 | 2005-02-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
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1W4O
 | | Binding of Nonnatural 3'-Nucleotides to Ribonuclease A | | 分子名称: | PANCREATIC RIBONUCLEASE A, URACIL ARABINOSE-3'-PHOSPHATE | | 著者 | Jenkins, C.L, Thiyagarajan, N, Sweeney, R.Y, Guy, M.P, Kelemen, B.R, Acharya, K.R, Raines, R.T. | | 登録日 | 2004-07-27 | | 公開日 | 2005-02-02 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Binding of Non-Natural 3'-Nucleotides to Ribonuclease A
FEBS J., 272, 2005
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1JN4
 | | The Crystal Structure of Ribonuclease A in complex with 2'-deoxyuridine 3'-pyrophosphate (P'-5') adenosine | | 分子名称: | ADENOSINE-5'-[TRIHYDROGEN DIPHOSPHATE] P'-3'-ESTER WITH 2'-DEOXYURIDINE, Pancreatic Ribonuclease A | | 著者 | Jardine, A.M, Leonidas, D.D, Jenkins, J.L, Park, C, Raines, R.T, Acharya, K.R, Shapiro, R. | | 登録日 | 2001-07-23 | | 公開日 | 2003-06-03 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Cleavage of 3',5'-Pyrophosphate-Linked Dinucleotides by Ribonuclease A and Angiogenin
Biochemistry, 40, 2001
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1MGR
 | | Crystal structure of RNase Sa3,cytotoxic microbial ribonuclease | | 分子名称: | Guanyl-specific ribonuclease Sa3, SULFATE ION | | 著者 | Sevcik, J, Urbanikova, L, Leland, P.A, Raines, R.T. | | 登録日 | 2002-08-16 | | 公開日 | 2003-02-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Links X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
J.Biol.Chem., 277, 2002
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1MGW
 | | Crystal structure of RNase Sa3, cytotoxic microbial ribonuclease | | 分子名称: | Guanyl-specific ribonuclease Sa3, LITHIUM ION | | 著者 | Sevcik, J, Urbanikova, L, Leland, P.A, Raines, R.T. | | 登録日 | 2002-08-16 | | 公開日 | 2003-02-04 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Links X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
J.Biol.Chem., 277, 2002
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1C8W
 | | THR45GLY VARIANT OF RIBONUCLEASE A | | 分子名称: | ACETATE ION, CHLORIDE ION, PROTEIN (Ribonuclease A) | | 著者 | Kelemen, B.R, Sweeney, R.T, Schultz, L.W, Raines, R.T. | | 登録日 | 1999-07-30 | | 公開日 | 2002-05-01 | | 最終更新日 | 2018-03-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Excavating an active site: the nucleobase specificity of ribonuclease A.
Biochemistry, 39, 2000
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1C9X
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1C9V
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