6F8T
 
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-4a | | 分子名称: | (2~{R})-1-[(~{E})-(3-cyclopentyloxy-4-methoxy-phenyl)methylideneamino]oxy-3-[(2~{R},6~{S})-2,6-dimethylmorpholin-4-yl]propan-2-ol, MAGNESIUM ION, ZINC ION, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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6F8V
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-18b | | 分子名称: | 3-[3-(3-cyclopentyloxy-4-methoxy-phenyl)pyrazol-1-yl]-1-[(2~{R},6~{R})-2,6-dimethylmorpholin-4-yl]propan-1-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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6F8U
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-20b | | 分子名称: | 2-[(~{E})-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]methylideneamino]oxy-1-[(2~{R},6~{R})-2,6-dimethylmorpholin-4-yl]ethanone, MAGNESIUM ION, ZINC ION, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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6F8X
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-26g | | 分子名称: | 1,2-ETHANEDIOL, 2-[(5~{R})-3-(3-cyclopentyloxy-4-methoxy-phenyl)-4,5-dihydro-1,2-oxazol-5-yl]-~{N},~{N}-bis(2-hydroxyethyl)ethanamide, DIMETHYL SULFOXIDE, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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6F8R
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-54 | | 分子名称: | (2~{S})-1-[3-(3-cyclopentyloxy-4-methoxy-phenyl)pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol, 1,2-ETHANEDIOL, MAGNESIUM ION, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-13 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.826 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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6FDC
 | | Crystal structure of the PDE4D catalytic domain in complex with GEBR-32a | | 分子名称: | (2~{R})-1-[3-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol, (2~{S})-1-[5-[4-[bis(fluoranyl)methoxy]-3-cyclopentyloxy-phenyl]pyrazol-1-yl]-3-morpholin-4-yl-propan-2-ol, 1,2-ETHANEDIOL, ... | | 著者 | Prosdocimi, T, Donini, S, Parisini, E. | | 登録日 | 2017-12-22 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Molecular Bases of PDE4D Inhibition by Memory-Enhancing GEBR Library Compounds.
Biochemistry, 57, 2018
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1RQF
 | | Structure of CK2 beta subunit crystallized in the presence of a p21WAF1 peptide | | 分子名称: | Casein kinase II beta chain, Disordered segment of Cyclin-dependent kinase inhibitor 1, UNKNOWN, ... | | 著者 | Bertrand, L, Sayed, M.F, Pei, X.-Y, Parisini, E, Dhanaraj, V, Bolanos-Garcia, V.M, Allende, J.E, Blundell, T.L. | | 登録日 | 2003-12-05 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structure of the regulatory subunit of CK2 in the presence of a p21WAF1 peptide demonstrates flexibility of the acidic loop.
Acta Crystallogr.,Sect.D, 60, 2004
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8BJY
 | | Engineered Fructosyl Peptide Oxidase - X02B mutant | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl Peptide Oxidase mutant (X02B), GLYCEROL | | 著者 | Estiri, H, Bhattacharya, S, Rodriguez-Buitrago, J.A, Parisini, E. | | 登録日 | 2022-11-08 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.475 Å) | | 主引用文献 | Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition.
Sci Rep, 13, 2023
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8BLX
 | | Engineered Fructosyl Peptide Oxidase - X02A mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl Peptide Oxidase mutant (X02A), ... | | 著者 | Estiri, H, Bhattacharya, S, Rodriguez-Buitrago, J.A, Parisini, E. | | 登録日 | 2022-11-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition.
Sci Rep, 13, 2023
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8BMU
 | | Engineered Fructosyl Peptide Oxidase - X04 mutant | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl Peptide Oxidase mutant (X04), ... | | 著者 | Estiri, H, Bhattacharya, S, Rodriguez-Buitrago, J.A, Parisini, E. | | 登録日 | 2022-11-11 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition.
Sci Rep, 13, 2023
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8BLZ
 | | Engineered Fructosyl Peptide Oxidase - D02 mutant | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl Peptide Oxidase mutant (D02), GLYCEROL, ... | | 著者 | Estiri, H, Bhattacharya, S, Rodriguez-Buitrago, J.A, Parisini, E. | | 登録日 | 2022-11-10 | | 公開日 | 2023-11-22 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Tailoring FPOX enzymes for enhanced stability and expanded substrate recognition.
Sci Rep, 13, 2023
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5OC3
 | | Crystal structure of Ser67Cys/Pro121Cys Amadoriase I mutant from Aspergillus Fumigatus | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine:oxygen oxidoreductase, GLYCEROL | | 著者 | Rigoldi, F, Donini, S, Gautieri, A, Parisini, E. | | 登録日 | 2017-06-29 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.153 Å) | | 主引用文献 | Thermal stabilization of the deglycating enzyme Amadoriase I by rational design.
Sci Rep, 8, 2018
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5OC2
 | | Crystal structure of Asp295Cys/Lys303Cys Amadoriase I mutant from Aspergillus Fumigatus | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Fructosyl amine:oxygen oxidoreductase | | 著者 | Rigoldi, F, Donini, S, Gautieri, A, Parisini, E. | | 登録日 | 2017-06-29 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Thermal stabilization of the deglycating enzyme Amadoriase I by rational design.
Sci Rep, 8, 2018
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1B0Y
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1AWD
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