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BU of 4r8l by Molmil

Crystal structure of the Asp-bound guinea pig L-asparaginase 1 catalytic domain
分子名称:	ASPARTIC ACID, Uncharacterized protein
著者	Schalk, A.M, Lavie, A.
登録日	2014-09-02
公開日	2014-10-22
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.41 Å)
主引用文献	Identification and Structural Analysis of an l-Asparaginase Enzyme from Guinea Pig with Putative Tumor Cell Killing Properties. J.Biol.Chem., 289, 2014

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BU of 4r8k by Molmil

Crystal structure of the guinea pig L-asparaginase 1 catalytic domain
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Uncharacterized protein
著者	Schalk, A.M, Lavie, A.
登録日	2014-09-02
公開日	2014-10-22
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Identification and Structural Analysis of an l-Asparaginase Enzyme from Guinea Pig with Putative Tumor Cell Killing Properties. J.Biol.Chem., 289, 2014

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BU of 4q18 by Molmil

Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 4 [1-[5-(4-{[(2,6-diaminopyrimidin-4-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]-2-methylpropan-2-ol]
分子名称:	1-(5-(4-(((2,6-diaminopyrimidin-4-yl)thio)methyl)-5-propylthiazol-2-yl)-2-methoxyphenoxy)-2-methylpropan-2-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者	Nomme, J, Lavie, A.
登録日	2014-04-03
公開日	2014-11-05
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. J.Med.Chem., 57, 2014

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BU of 4q1e by Molmil

Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 10 {2-{[(1R/S)-1-{2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol 4-yl}ethyl]sulfanyl}pyrimidine-4,6-diamine}
分子名称:	(R)-2-((1-(2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine, (S)-2-((1-(2-(3-(2-fluoroethoxy)-4-methoxyphenyl)-5-methylthiazol-4-yl)ethyl)thio)pyrimidine-4,6-diamine, Deoxycytidine kinase, ...
著者	Nomme, J, Lavie, A.
登録日	2014-04-03
公開日	2014-11-05
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.85 Å)
主引用文献	Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. J.Med.Chem., 57, 2014

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BU of 4q1a by Molmil

Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 6 {2-[5-(4-{[(4,6-diaminopyrimidin-2-yl)sulfanyl]methyl}-5-propyl-1,3-thiazol-2-yl)-2-methoxyphenoxy]ethanol}
分子名称:	2-(5-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)-2-methoxyphenoxy)ethan-1-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE
著者	Nomme, J, Lavie, A.
登録日	2014-04-03
公開日	2015-02-18
最終更新日	2023-09-20
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. J.Med.Chem., 57, 2014

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BU of 7s0s by Molmil

M. tuberculosis ribosomal RNA methyltransferase TlyA bound to M. smegmatis 50S ribosomal subunit
分子名称:	16S/23S rRNA (Cytidine-2'-O)-methyltransferase TlyA, 23S rRNA, 50S ribosomal protein L10, ...
著者	Laughlin, Z.T, Dunham, C.M, Conn, G.L.
登録日	2021-08-31
公開日	2022-03-30
最終更新日	2024-06-05
実験手法	ELECTRON MICROSCOPY (3.05 Å)
主引用文献	50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA. Proc.Natl.Acad.Sci.USA, 119, 2022

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件を2024-07-31に公開中

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