1RCN
 
 | | CRYSTAL STRUCTURE OF THE RIBONUCLEASE A D(APTPAPAPG) COMPLEX : DIRECT EVIDENCE FOR EXTENDED SUBSTRATE RECOGNITION | | 分子名称: | DNA (5'-D(*AP*TP*AP*A)-3'), PROTEIN (RIBONUCLEASE A (E.C.3.1.27.5)) | | 著者 | Fontecilla-Camps, J.C, De Llorens, R, Le Du, M.H, Cuchillo, C.M. | | 登録日 | 1994-05-27 | | 公開日 | 1994-09-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition.
J.Biol.Chem., 269, 1994
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2GLQ
 | | X-ray structure of human alkaline phosphatase in complex with strontium | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Alkaline phosphatase, placental type, ... | | 著者 | Llinas, P, Masella, M, Stigbrand, T, Menez, A, Stura, E.A, Le Du, M.H. | | 登録日 | 2006-04-05 | | 公開日 | 2006-04-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural studies of human alkaline phosphatase in complex with strontium: Implication for its secondary effect in bones.
Protein Sci., 15, 2006
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2HEO
 | | General Structure-Based Approach to the Design of Protein Ligands: Application to the Design of Kv1.2 Potassium Channel Blockers. | | 分子名称: | 5'-D(*TP*CP*GP*CP*GP*CP*G)-3', Z-DNA binding protein 1 | | 著者 | Magis, C, Gasparini, S, Charbonnier, J.B, Stura, E, Le Du, M.H, Menez, A, Cuniasse, P. | | 登録日 | 2006-06-21 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based secondary structure-independent approach to design protein ligands: Application to the design of Kv1.2 potassium channel blockers.
J.Am.Chem.Soc., 128, 2006
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2H7Z
 | | Crystal structure of irditoxin | | 分子名称: | Irditoxin subunit A, Irditoxin subunit B | | 著者 | Pawlak, J, Kini, R.M, Stura, E.A, Le Du, M.H. | | 登録日 | 2006-06-06 | | 公開日 | 2006-08-29 | | 最終更新日 | 2011-10-05 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Irditoxin, a novel covalently linked heterodimeric three-finger toxin with high taxon-specific neurotoxicity.
Faseb J., 23, 2009
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3G5H
 | | Crystallographic analysis of cytochrome P450 cyp121 | | 分子名称: | (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Belin, P, Le Du, M.H, Gondry, M. | | 登録日 | 2009-02-05 | | 公開日 | 2009-04-21 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.USA, 106, 2009
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3G5F
 | | Crystallographic analysis of cytochrome P450 cyp121 | | 分子名称: | Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | 著者 | Belin, P, Le Du, M.H, Gondry, M. | | 登録日 | 2009-02-05 | | 公開日 | 2009-04-21 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Identification and structural basis of the reaction catalyzed by CYP121, an essential cytochrome P450 in Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.USA, 106, 2009
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7ABM
 | | X-ray structure of phosphorylated Barrier-to-autointegration factor (BAF) | | 分子名称: | Barrier-to-autointegration factor, CESIUM ION | | 著者 | Zinn-Justin, S, Marcelot, A, Le Du, M.H, Ropars, V. | | 登録日 | 2020-09-08 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | | 主引用文献 | Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Nucleic Acids Res., 49, 2021
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1IQ9
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7NDY
 | | Di-phosphorylated Barrier-to-Autointegration Factor (BAF) in complex with LEM domain of Emerin | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Barrier-to-autointegration factor, N-terminally processed, ... | | 著者 | Marcelot, A, Le Du, M.H, Hoffmann, G, Zinn-Justin, S. | | 登録日 | 2021-02-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Di-phosphorylated BAF shows altered structural dynamics and binding to DNA, but interacts with its nuclear envelope partners.
Nucleic Acids Res., 49, 2021
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4GFB
 | | Rap1/DNA complex | | 分子名称: | CALCIUM ION, DNA-binding protein RAP1, telomeric DNA | | 著者 | Le Bihan, Y.-V, Matot, B, Le Du, M.-H. | | 登録日 | 2012-08-03 | | 公開日 | 2013-04-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Effect of Rap1 binding on DNA distortion and potassium permanganate hypersensitivity.
Acta Crystallogr.,Sect.D, 69, 2013
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4FMN
 | | Structure of the C-terminal domain of the Saccharomyces cerevisiae MUTL alpha (MLH1/PMS1) heterodimer bound to a fragment of NTG2 | | 分子名称: | 1,2-ETHANEDIOL, DNA mismatch repair protein MLH1, DNA mismatch repair protein PMS1, ... | | 著者 | Gueneau, E, Legrand, P, Charbonnier, J.B. | | 登録日 | 2012-06-18 | | 公開日 | 2013-02-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Structure of the MutL alpha C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site.
Nat.Struct.Mol.Biol., 20, 2013
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2OBH
 | | Centrin-XPC peptide | | 分子名称: | CALCIUM ION, Centrin-2, DNA-repair protein complementing XP-C cells | | 著者 | Charbonnier, J.B. | | 登録日 | 2006-12-19 | | 公開日 | 2007-10-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural, thermodynamic, and cellular characterization of human centrin 2 interaction with xeroderma pigmentosum group C protein.
J.Mol.Biol., 373, 2007
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1FG9
 | | 3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER | | 分子名称: | INTERFERON GAMMA, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN | | 著者 | Thiel, D.J, le Du, M.-H, Walter, R.L, D'Arcy, A, Chene, C, Fountoulakis, M, Garotta, G, Winkler, F.K, Ealick, S.E. | | 登録日 | 2000-07-28 | | 公開日 | 2000-08-11 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
Structure Fold.Des., 8, 2000
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4ICT
 | | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | | 分子名称: | (3S,6S)-3-benzyl-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Fonvielle, M, Le Du, M.-H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | | 登録日 | 2012-12-11 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
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3UKG
 | | Crystal structure of Rap1/DNA complex | | 分子名称: | CALCIUM ION, DNA-binding protein RAP1, telomeric DNA | | 著者 | Matot, B, Le Bihan, Y.-V, Gasparini, S, LeDu, M.H. | | 登録日 | 2011-11-09 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNA.
Nucleic Acids Res., 40, 2012
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4A3T
 | | yeast regulatory particle proteasome assembly chaperone Hsm3 | | 分子名称: | DNA MISMATCH REPAIR PROTEIN HSM3 | | 著者 | Richet, N, Barrault, M.B, Godart, C, Murciano, B, Le Tallec, B, Rousseau, E, Ledu, M.H, Charbonnier, J.B, Legrand, P, Guerois, R, Peyroche, A, Ochsenbein, F. | | 登録日 | 2011-10-04 | | 公開日 | 2012-04-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Dual Functions of the Hsm3 Protein in Chaperoning and Scaffolding Regulatory Particle Subunits During the Proteasome Assembly.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4RQI
 | | Structure of TRF2/RAP1 secondary interaction binding site | | 分子名称: | GLYCEROL, MAGNESIUM ION, Telomeric repeat-binding factor 2, ... | | 著者 | Miron, S, Guimaraes, B, Gaullier, G, Giraud-Panis, M.-J, Gilson, E, Le Du, M.-H. | | 登録日 | 2014-11-03 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.4405 Å) | | 主引用文献 | A higher-order entity formed by the flexible assembly of RAP1 with TRF2.
Nucleic Acids Res., 44, 2016
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1FSS
 | | ACETYLCHOLINESTERASE (E.C. 3.1.1.7) COMPLEXED WITH FASCICULIN-II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, FASCICULIN II, ... | | 著者 | Harel, M, Kleywegt, G.J, Silman, I, Sussman, J.L. | | 登録日 | 1995-10-25 | | 公開日 | 1996-03-08 | | 最終更新日 | 2021-06-02 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target.
Structure, 3, 1995
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6GHD
 | | Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases | | 分子名称: | 1,2-ETHANEDIOL, Barrier-to-autointegration factor, Emerin, ... | | 著者 | Samson, C, Petitalot, A, Celli, F, Herrada, I, Ropars, V, Ledu, M.H, Nhiri, N, Arteni, A.A, Buendia, B, ZinnJustin, S. | | 登録日 | 2018-05-07 | | 公開日 | 2018-08-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Nucleic Acids Res., 46, 2018
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4IPS
 | | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | | 分子名称: | (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazin-2-one, Cytochrome P450 121, GLYCEROL, ... | | 著者 | Fonvielle, M, LeDu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | | 登録日 | 2013-01-10 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
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4IPW
 | | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | | 分子名称: | (3S,6S)-3-(3,4-dihydroxybenzyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... | | 著者 | Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | | 登録日 | 2013-01-10 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
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4IQ7
 | | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | | 分子名称: | (3S,6S)-3-(4-hydroxybenzyl)-6-methylpiperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | | 登録日 | 2013-01-11 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
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4IQ9
 | | Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 | | 分子名称: | (3S,6S)-3-(4-hydroxybenzyl)-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... | | 著者 | Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. | | 登録日 | 2013-01-11 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES.
J.Biol.Chem., 288, 2013
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3OQV
 | | AlbC, a cyclodipeptide synthase from Streptomyces noursei | | 分子名称: | AlbC, DITHIANE DIOL, PHOSPHATE ION | | 著者 | Sauguet, L, Ledu, M.H, Charbonnier, J.B, Gondry, M. | | 登録日 | 2010-09-04 | | 公開日 | 2011-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cyclodipeptide synthases, a family of class-I aminoacyl-tRNA synthetase-like enzymes involved in non-ribosomal peptide synthesis.
Nucleic Acids Res., 39, 2011
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6RMN
 | | DNA mismatch repair proteins MLH1 and MLH3 | | 分子名称: | DNA mismatch repair protein MLH1, DNA mismatch repair protein MLH3, ZINC ION | | 著者 | Dai, J, Chervy, P, Legrand, P, Ropars, V, Charbonnier, J.B. | | 登録日 | 2019-05-07 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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