7ZZW
 
 | | Ligand binding to HDAC2 | | 分子名称: | 1,2-ETHANEDIOL, 2-(cyclohexylazaniumyl)ethanesulfonate, CALCIUM ION, ... | | 著者 | Cleasby, A, Tisi, D. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.
Acs Med.Chem.Lett., 13, 2022
|
|
8A0B
 | | Inhibitor binding to HDAC2 | | 分子名称: | 1,2-ETHANEDIOL, 1,3-dihydroisoindol-2-yl-[(2R,4S)-4-phenylpyrrolidin-1-ium-2-yl]methanone, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | | 著者 | Cleasby, A, Tisi, D. | | 登録日 | 2022-05-27 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.746 Å) | | 主引用文献 | Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.
Acs Med.Chem.Lett., 13, 2022
|
|
7ZZS
 | | HDAC2 complexed with an inhibitory ligand | | 分子名称: | (5~{S})-5-(4-chlorophenyl)pyrrolidin-2-one, 1,2-ETHANEDIOL, 2-(cyclohexylazaniumyl)ethanesulfonate, ... | | 著者 | Cleasby, A, Tisi, D. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.
Acs Med.Chem.Lett., 13, 2022
|
|
7ZZU
 | | Inhibitory Ligand binding to HDAC2 | | 分子名称: | 1,2-ETHANEDIOL, 2-[4-[(2~{R},4~{S})-4-phenylpyrrolidin-2-yl]carbonylpiperazin-1-yl]pyridine-3-carbonitrile, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ... | | 著者 | Cleasby, A, Tisi, D. | | 登録日 | 2022-05-26 | | 公開日 | 2022-09-21 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor.
Acs Med.Chem.Lett., 13, 2022
|
|
8JJS
 | | Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | | 著者 | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | | 登録日 | 2023-05-31 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.534 Å) | | 主引用文献 | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor.
J.Am.Chem.Soc., 145, 2023
|
|
5WPH
 | | Crystal structure of ArsN, N-acetyltransferase with substrate AST from Pseudomonas putida KT2440 | | 分子名称: | (2S)-2-amino-4-[hydroxy(methyl)arsoryl]butanoic acid, Phosphinothricin N-acetyltransferase, SODIUM ION | | 著者 | Venkadesh, S, Dheeman, D.S, Yoshinaga, M, Kandavelu, P, Rosen, B.P. | | 登録日 | 2017-08-04 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic.
Commun Biol, 2, 2019
|
|
6M7G
 | | Crystal structure of ArsN, N-acetyltransferase with substrate phosphinothricin from Pseudomonas putida KT2440 | | 分子名称: | PHOSPHINOTHRICIN, Phosphinothricin N-acetyltransferase | | 著者 | Venkadesh, S, Dheeman, D.S, Yoshinaga, M, Kandavelu, P, Rosen, B.P. | | 登録日 | 2018-08-20 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.657 Å) | | 主引用文献 | Arsinothricin, an arsenic-containing non-proteinogenic amino acid analog of glutamate, is a broad-spectrum antibiotic.
Commun Biol, 2, 2019
|
|
2ZXT
 | | Crystal structure of Tim40/MIA40, a disulfide relay system in mitochondria, solved as MBP fusion protein | | 分子名称: | Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ... | | 著者 | Kawano, S, Momose, T, Watanabe, N, Endo, T. | | 登録日 | 2009-01-07 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3BOY
 | | Crystal structure of the HutP antitermination complex bound to the HUT mRNA | | 分子名称: | 5'-R(*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*UP*UP*UP*AP*GP*UP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ... | | 著者 | Kumarevel, T.S, Balasundaresan, D, Jeyakanthan, J, Shinkai, A, Yokoyama, S, Kumar, P.K.R, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2007-12-18 | | 公開日 | 2008-01-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of HutP complexed with the 55-mer RNA
To be Published
|
|
6K84
 | | Structure of anti-prion RNA aptamer | | 分子名称: | RNA (25-MER) | | 著者 | Mashima, T, Lee, J.H, Hayashi, T, Nagata, T, Kinoshita, M, Katahira, M. | | 登録日 | 2019-06-11 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Development and structural determination of an anti-PrPCaptamer that blocks pathological conformational conversion of prion protein.
Sci Rep, 10, 2020
|
|
3A3C
 | | Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant | | 分子名称: | Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ... | | 著者 | Kawano, S, Naoe, M, Momose, T, Watanabe, N, Endo, T. | | 登録日 | 2009-06-11 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
5YV5
 | | Crystal structure of the complex of archaeal ribosomal stalk protein aP1 and archaeal ribosome recycling factor aABCE1. | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ATPase RIL, Archaeal ribosomal stalk protein aP1, ... | | 著者 | Imai, H, Abe, T, Miyoshi, T, Nishikawa, S, Ito, K, Uchiumi, T. | | 登録日 | 2017-11-24 | | 公開日 | 2018-07-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The ribosomal stalk protein is crucial for the action of the conserved ATPase ABCE1
Nucleic Acids Res., 46, 2018
|
|
1VEA
 | | Crystal Structure of HutP, an RNA binding antitermination protein | | 分子名称: | Hut operon positive regulatory protein, N-(2-NAPHTHYL)HISTIDINAMIDE | | 著者 | Kumarevel, T.S, Fujimoto, Z, Karthe, P, Oda, M, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-03-29 | | 公開日 | 2004-07-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structure of Activated HutP; An RNA Binding Protein that Regulates Transcription of the hut Operon in Bacillus subtilis
Structure, 12, 2004
|
|
1WRQ
 | |
1WPT
 | | Crystal Structure of HutP, an RNA binding anti-termination protein | | 分子名称: | Hut operon positive regulatory protein | | 著者 | Kumarevel, T, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-09-13 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
Nucleic Acids Res., 33, 2005
|
|
1WMQ
 | | Structure of the HutP antitermination complex bound to a single stranded region of hut mRNA | | 分子名称: | 5'-R(P*UP*UP*UP*AP*GP*UP*U)-3', HISTIDINE, Hut operon positive regulatory protein, ... | | 著者 | Kumarevel, T.S, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-07-14 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand.
Nature, 434, 2005
|
|
1WPV
 | | Crystal Structure of Activated Binary complex of HutP, an RNA binding anti-termination protein | | 分子名称: | HISTIDINE, Hut operon positive regulatory protein, MAGNESIUM ION | | 著者 | Kumarevel, T.S, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-09-14 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of HutP-mediated anti-termination and roles of the Mg2+ ion and L-histidine ligand.
Nature, 434, 2005
|
|
1WPU
 | |
1WRO
 | | Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis | | 分子名称: | BARIUM ION, HISTIDINE, Hut operon positive regulatory protein | | 著者 | Kumarevel, T, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-10-25 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
Nucleic Acids Res., 33, 2005
|
|
1WRN
 | | Metal Ion dependency of the antiterminator protein, HutP, for binding to the terminator region of hut mRNA- A structural basis | | 分子名称: | DI(HYDROXYETHYL)ETHER, HISTIDINE, Hut operon positive regulatory protein, ... | | 著者 | Kumarevel, T, Mizuno, H, Kumar, P.K.R. | | 登録日 | 2004-10-25 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of the metal ion binding site in the anti-terminator protein, HutP, of Bacillus subtilis
Nucleic Acids Res., 33, 2005
|
|
1WPS
 | |
2ZE4
 | | Crystal structure of phospholipase D from streptomyces antibioticus | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Phospholipase D | | 著者 | Suzuki, A, Kakuno, K, Saito, R, Iwasaki, Y, Yamane, T, Yamane, T. | | 登録日 | 2007-12-05 | | 公開日 | 2007-12-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of phospholipase D from streptomyces antibioticus
To be Published
|
|
2ZE9
 | | Crystal structure of H168A mutant of phospholipase D from Streptomyces antibioticus, as a complex with phosphatidylcholine | | 分子名称: | (2R)-3-(phosphonooxy)propane-1,2-diyl diheptanoate, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Phospholipase D | | 著者 | Suzuki, A, Toda, H, Iwasaki, Y, Yamane, T, Yamane, T. | | 登録日 | 2007-12-06 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of phospholipase D from streptomyces antibioticus
To be Published
|
|
