3E16
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![BU of 3e16 by Molmil](/molmil-images/mine/3e16) | X-ray structure of human prostasin in complex with Benzoxazole warhead peptidomimic, lysine in P3 | 分子名称: | DIMETHYL SULFOXIDE, GLYCEROL, Prostasin, ... | 著者 | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | 登録日 | 2008-08-01 | 公開日 | 2008-09-09 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg.Med.Chem.Lett., 18, 2008
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3E0P
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![BU of 3e0p by Molmil](/molmil-images/mine/3e0p) | The X-ray structure of Human Prostasin in complex with a covalent benzoxazole inhibitor | 分子名称: | GLYCEROL, Prostasin, benzyl [(1R)-1-({(2S,4R)-2-({(1S)-5-amino-1-[(S)-1,3-benzoxazol-2-yl(hydroxy)methyl]pentyl}carbamoyl)-4-[(4-methylbenzyl)oxy]pyrrolidin-1-yl}carbonyl)-3-phenylpropyl]carbamate | 著者 | Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. | 登録日 | 2008-07-31 | 公開日 | 2008-09-09 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of inhibitors of the channel-activating protease prostasin (CAP1/PRSS8) utilizing structure-based design. Bioorg.Med.Chem.Lett., 18, 2008
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2F1G
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![BU of 2f1g by Molmil](/molmil-images/mine/2f1g) | Cathepsin S in complex with non-covalent 2-(Benzoxazol-2-ylamino)-acetamide | 分子名称: | Cathepsin S, GLYCEROL, N~2~-1,3-BENZOXAZOL-2-YL-3-CYCLOHEXYL-N-{2-[(4-METHOXYPHENYL)AMINO]ETHYL}-L-ALANINAMIDE | 著者 | Spraggon, G, Hornsby, M, Lesley, S.A, Tully, D.C, Harris, J.L, Karenewsky, D.S, Kulathila, R, Clark, K. | 登録日 | 2005-11-14 | 公開日 | 2006-04-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: Heterocyclic P3. Bioorg.Med.Chem.Lett., 16, 2006
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