1N45
 
 | | X-RAY CRYSTAL STRUCTURE OF HUMAN HEME OXYGENASE-1 (HO-1) IN COMPLEX WITH ITS SUBSTRATE HEME | | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, heme oxygenase 1 | | 著者 | Schuller, D.J, Wilks, A, Ortiz de Montellano, P.R, Poulos, T.L. | | 登録日 | 2002-10-30 | | 公開日 | 2002-11-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1.
J. Biol. Chem., 278, 2003
|
|
8Q8N
 | | Crystal structure of human GPX4-U46C-I129S-L130S | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
|
|
8Q8J
 | | Crystal structure of human GPX4-R152H | | 分子名称: | Glutathione peroxidase | | 著者 | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human GPX4-R152H
To Be Published
|
|
1N3U
 | | Crystal structure of human heme oxygenase 1 (HO-1) in complex with its substrate heme, crystal form B | | 分子名称: | CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, heme oxygenase 1 | | 著者 | Lad, L, Schuller, D.J, Friedman, J.P, Li, H, Ortiz de Montellano, P.R, Poulos, T.L. | | 登録日 | 2002-10-29 | | 公開日 | 2002-11-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Comparison of the heme-free and -bound crystal structures of human heme oxygenase-1
J.Biol.Chem., 278, 2003
|
|
2O8Y
 | | Apo IRAK4 Kinase Domain | | 分子名称: | Interleukin-1 receptor-associated kinase 4 | | 著者 | Boriack-Sjodin, P.A, Mol, C. | | 登録日 | 2006-12-12 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of the apo and inhibited IRAK4 kinase domain
To be Published
|
|
3PWY
 | | Crystal structure of an extender (SPD28345)-modified human PDK1 complex 2 | | 分子名称: | 3-phosphoinositide-dependent protein kinase 1, N-[2-({6-[(2-sulfanylethyl)amino]pyrimidin-4-yl}amino)ethyl]propanamide | | 著者 | Elling, R.A, Penny, D.M, Simmons, R.L, Erlanson, D.A, Romanowski, M.J. | | 登録日 | 2010-12-09 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
3QC4
 | | PDK1 in complex with DFG-OUT inhibitor xxx | | 分子名称: | 1-(3,4-difluorobenzyl)-2-oxo-N-{(1R)-2-[(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)oxy]-1-phenylethyl}-1,2-dihydropyridine-3-carboxamide, 3-phosphoinositide-dependent protein kinase 1 | | 著者 | Arndt, J.W. | | 登録日 | 2011-01-15 | | 公開日 | 2011-04-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
3ADK
 | |
