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8SCJ
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BU of 8scj by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCL
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BU of 8scl by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 6h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCI
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BU of 8sci by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCK
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BU of 8sck by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCG
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BU of 8scg by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 0h (Ground State)
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 3'-Amino DNA Primer, CALCIUM ION, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCM
DownloadVisualize
BU of 8scm by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCN
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BU of 8scn by Molmil
Bst DNA polymerase I Large Fragment mutant F710Y/D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h (Product State)
分子名称: CALCIUM ION, DIPHOSPHATE, DNA polymerase I, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCO
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BU of 8sco by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 0h (Ground State)
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 3'-Amino DNA primer, CALCIUM ION, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCP
DownloadVisualize
BU of 8scp by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 1h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCQ
DownloadVisualize
BU of 8scq by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 2h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCR
DownloadVisualize
BU of 8scr by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 4h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCS
DownloadVisualize
BU of 8scs by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 8h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCT
DownloadVisualize
BU of 8sct by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 24h
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
8SCU
DownloadVisualize
BU of 8scu by Molmil
Bst DNA polymerase I Large Fragment wildtype D598A with 3'-amino primer, dGTP, and calcium time-resolved 48h (Product State)
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Fang, Z, Lelyveld, V.S, Szostak, J.W.
登録日2023-04-05
公開日2023-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Trivalent rare earth metal cofactors confer rapid NP-DNA polymerase activity.
Science, 382, 2023
7KUO
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BU of 7kuo by Molmil
FANA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(GFL))-3')
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.281 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KUN
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BU of 7kun by Molmil
2'-F modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*C)-D(P*(GF2))-3')
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KUK
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BU of 7kuk by Molmil
High resolution RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KUM
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BU of 7kum by Molmil
LNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: 5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(LCG)-3', DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.714 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KUL
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BU of 7kul by Molmil
DNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: DIGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*C)-D(P*G)-3'), MAGNESIUM ION
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
7KUP
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BU of 7kup by Molmil
2'-OMe modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G
分子名称: 5'-R((LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(OMG))-3', DIGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Fang, Z, Giurgiu, C, Szostak, J.W.
登録日2020-11-25
公開日2021-09-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Structure-Activity Relationships in Nonenzymatic Template-Directed RNA Synthesis.
Angew.Chem.Int.Ed.Engl., 60, 2021
8TDZ
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BU of 8tdz by Molmil
16mer self-complementary duplex RNA with D:U pair sequence 2
分子名称: COBALT HEXAMMINE(III), RNA
著者Fang, Z, Jia, X, Szostak, J.W.
登録日2023-07-05
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
8TE0
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BU of 8te0 by Molmil
16mer self-complementary duplex RNA with D:C pair sequence 1
分子名称: MAGNESIUM ION, RNA
著者Fang, Z, Jia, X, Szostak, J.W.
登録日2023-07-05
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
8TDY
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BU of 8tdy by Molmil
16mer self-complementary duplex RNA with D:U pair sequence 1
分子名称: MAGNESIUM ION, RNA
著者Fang, Z, Jia, X, Szostak, J.W.
登録日2023-07-05
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
8TE2
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BU of 8te2 by Molmil
16mer self-complementary duplex RNA with D:C pair sequence 2
分子名称: CALCIUM ION, RNA
著者Fang, Z, Jia, X, Szostak, J.W.
登録日2023-07-05
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Diaminopurine in Nonenzymatic RNA Template Copying.
J.Am.Chem.Soc., 146, 2024
7U8B
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BU of 7u8b by Molmil
Product of 14mer primer with activated asymmetric GA dimer diastereomer 1
分子名称: 5'-O-[(S)-(2-amino-1H-imidazol-1-yl)(hydroxy)phosphoryl]adenosine, RNA (5'-R(*(TLN)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3'), SULFATE ION
著者Fang, Z, Szostak, J.W.
登録日2022-03-08
公開日2023-03-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Understanding the metal ion function in the RNA non-enzymatic extesion with phosphorothioates
To Be Published

222415

件を2024-07-10に公開中

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