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4FS2
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BU of 4fs2 by Molmil
Base pairing mechanism of N2,3-ethenoguanine with dCTP by human polymerase iota
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*TP*CP*TP*(EFG)P*GP*GP*GP*TP*CP*CP*TP*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA polymerase iota, ...
著者Zhao, L.
登録日2012-06-26
公開日2012-08-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Basis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA Polymerases.
J.Biol.Chem., 287, 2012
4JV0
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BU of 4jv0 by Molmil
Ring-Opening of the -OH-PdG Adduct in Ternary Complexes with the Sulfolobus solfataricus DNA polymerase Dpo4
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), ...
著者Banerjee, S, Shanmugam, G, Stone, M.P.
登録日2013-03-25
公開日2013-08-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4.
Chem.Res.Toxicol., 26, 2013
4JV1
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BU of 4jv1 by Molmil
Ternary complex of gamma-OHPDG adduct modified dna with dna (-1 primer) polymerase iv and incoming dgtp
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*C)-3'), ...
著者Banerjee, S, Shanmugam, G, Stone, M.P.
登録日2013-03-25
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ring-Opening of the gamma-OH-PdG Adduct Promotes Error-Free Bypass by the Sulfolobus solfataricus DNA Polymerase Dpo4.
Chem.Res.Toxicol., 26, 2013
6NE5
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BU of 6ne5 by Molmil
Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors that Demonstrate in vivo Activity in Mouse Xenograft Models of Human Cancer
分子名称: 3-[(4R)-7-chloro-10-[3-(4-chloro-3,5-dimethylphenoxy)propyl]-4-methyl-1-oxo-6-(1,3,5-trimethyl-1H-pyrazol-4-yl)-3,4-dihydropyrazino[1,2-a]indol-2(1H)-yl]-1-methyl-1H-indole-5-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1
著者Zhao, B.
登録日2018-12-17
公開日2019-04-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer.
J.Med.Chem., 62, 2019
6NOS
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BU of 6nos by Molmil
PD-L1 IgV domain V76T with fragment
分子名称: 1-[5-(3,5-dichlorophenyl)furan-2-yl]-N-methylmethanamine, Programmed cell death 1 ligand 1
著者Zhao, B, Perry, E.
登録日2019-01-16
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
6NM8
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BU of 6nm8 by Molmil
IgV-V76T BMS compound 105
分子名称: N-({2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl}methyl)-D-alanine, Programmed cell death 1 ligand 1
著者Perry, E, Zhao, B, Fesik, S.
登録日2019-01-10
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.792 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
6NP9
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BU of 6np9 by Molmil
PD-L1 IgV domain V76T with fragment
分子名称: Programmed cell death 1 ligand 1, SULFATE ION
著者Zhao, B, Perry, E.
登録日2019-01-17
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
6NNV
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BU of 6nnv by Molmil
PD-L1 IgV domain complex with macro-cyclic peptide
分子名称: Programmed cell death 1 ligand 1, macrocyclic peptide
著者Zhao, B, Perry, E.
登録日2019-01-15
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
6NOJ
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BU of 6noj by Molmil
PD-L1 IgV domain V76T with fragment
分子名称: Programmed cell death 1 ligand 1, methyl 3-amino-4-(2-fluorophenyl)-1H-pyrrole-2-carboxylate
著者Zhao, B, Perry, E.
登録日2019-01-16
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
6NM7
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BU of 6nm7 by Molmil
PD-L1 IgV domain bound to fragment
分子名称: 5-phenylthieno[2,3-d]pyrimidin-4(3H)-one, Programmed cell death 1 ligand 1
著者Perry, E, Zhao, B.
登録日2019-01-10
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.426 Å)
主引用文献Fragment-based screening of programmed death ligand 1 (PD-L1).
Bioorg. Med. Chem. Lett., 29, 2019
3W0F
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BU of 3w0f by Molmil
Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3)
分子名称: Endonuclease 8-like 3, IODIDE ION, ZINC ION
著者Liu, M, Imamura, K, Averill, A.M, Wallace, S.S, Doublie, S.
登録日2012-10-30
公開日2013-01-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA
Structure, 21, 2013
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件を2024-08-14に公開中

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