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3LTC
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BU of 3ltc by Molmil
X-ray structure of a non-biological ATP binding protein determined in the presence of 10 mM ATP at 2.0 A by multi-wavelength anomalous dispersion
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ...
著者Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C.
登録日2010-02-15
公開日2010-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
3LT9
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BU of 3lt9 by Molmil
A non-biological ATP binding protein with a single point mutation (D65V), that contributes to optimized folding and ligand binding
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-D65V, CHLORIDE ION, ...
著者Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C.
登録日2010-02-15
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
3LTD
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BU of 3ltd by Molmil
X-ray structure of a non-biological ATP binding protein determined at 2.8 A by multi-wavelength anomalous dispersion
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ...
著者Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C.
登録日2010-02-15
公開日2010-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
3LTA
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BU of 3lta by Molmil
Crystal structure of a non-biological ATP binding protein with a TYR-PHE mutation within the ligand binding domain
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP BINDING PROTEIN-DX, CHLORIDE ION, ...
著者Simmons, C.R, Magee, C.L, Allen, J.P, Chaput, J.C.
登録日2010-02-15
公開日2010-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Three-dimensional structures reveal multiple ADP/ATP binding modes for a synthetic class of artificial proteins.
Biochemistry, 49, 2010
7K5T
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BU of 7k5t by Molmil
Bst DNA polymerase I time-resolved structure, 25.5 hr post dATP and dCTP addition
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5U
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BU of 7k5u by Molmil
Bst DNA polymerase I time-resolved structure, 48 hr post dATP and dCTP addition
分子名称: DNA (5'-D(P*CP*GP*AP*TP*CP*AP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5P
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BU of 7k5p by Molmil
Bst DNA polymerase I time-resolved structure, 4 min post dATP addition
分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5S
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BU of 7k5s by Molmil
Bst DNA polymerase I time-resolved structure, 4 hr post dATP and dCTP addition
分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*AP*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*C)-3'), DNA polymerase I, ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5O
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BU of 7k5o by Molmil
Bst DNA polymerase I time-resolved structure, 1 min post dATP addition
分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5R
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BU of 7k5r by Molmil
Bst DNA polymerase I time-resolved structure, 120 min post dATP addition
分子名称: DNA (5'-D(P*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
7K5Q
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BU of 7k5q by Molmil
Bst DNA polymerase I time-resolved structure, 8 min post dATP addition
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(P*G*CP*GP*AP*TP*CP*AP*CP*GP*T)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), ...
著者Chim, N, Meza, R.A, Trinh, A.M, Chaput, J.C.
登録日2020-09-17
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Following replicative DNA synthesis by time-resolved X-ray crystallography.
Nat Commun, 12, 2021
6U7Y
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BU of 6u7y by Molmil
RNA hairpin structure containing one TNA nucleotide as template
分子名称: CYTIDINE-5'-MONOPHOSPHATE, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*(TG)P*CP*CP*GP*AP*AP*AP*GP*G)-3')
著者Szostak, J.W, Zhang, W.
登録日2019-09-03
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.
Nucleic Acids Res., 49, 2021
7RSU
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BU of 7rsu by Molmil
TNA polymerase, n+2 product
分子名称: DNA polymerase, Primer, Template
著者Maola, V, Chaput, J, Chim, N.
登録日2021-08-11
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Synthesis and Polymerase Recognition of Threose Nucleic Acid Triphosphates Equipped with Diverse Chemical Functionalities.
J.Am.Chem.Soc., 143, 2021
8SKQ
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BU of 8skq by Molmil
RNA oligonucleotide containing an alpha-(L)-threofuranosyl nucleic acid (TNA)
分子名称: TNA-containing RNA oligonucleotide
著者Harp, J.M, Egli, M.
登録日2023-04-20
公開日2024-02-14
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Shorter Is Better: The alpha-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs.
J.Am.Chem.Soc., 145, 2023
6U7Z
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BU of 6u7z by Molmil
RNA hairpin structure containing one TNA nucleotide as primer
分子名称: CYTIDINE-5'-MONOPHOSPHATE, RNA (5'-R(*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3'), RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*GP*CP*CP*GP*AP*AP*AP*GP*(TG))-3')
著者Szostak, J.W, Zhang, W.
登録日2019-09-03
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.
Nucleic Acids Res., 49, 2021
6U8U
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BU of 6u8u by Molmil
RNA duplex bound with TNA 3'-3' imidazolium dimer
分子名称: 2-amino-3-[(R)-{[(3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}(hydroxy)phosphoryl]-1-[(S)-{[(3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-4-hydroxyoxolan-3-yl]oxy}(hydroxy)phosphoryl]-1H-imidazol-3-ium, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*G)-3')
著者Szostak, J.W, Zhang, W.
登録日2019-09-05
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.
Nucleic Acids Res., 49, 2021
6U89
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BU of 6u89 by Molmil
RNA duplex, bound with TNA monomer
分子名称: 2-azanyl-9-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-oxolan-2-yl]-1~{H}-purin-6-one, RNA (5'-R(*(LCC)P*(TLN)P*(LCG)P*UP*AP*CP*A)-3')
著者Szostak, J.W, Zhang, W.
登録日2019-09-04
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.
Nucleic Acids Res., 49, 2021
6U8F
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BU of 6u8f by Molmil
RNA hairpin, bound with TNA monomer
分子名称: 2-azanyl-9-[(2~{R},3~{R},4~{S})-3-oxidanyl-4-[oxidanyl-bis(oxidanylidene)-$l^{6}-phosphanyl]oxy-oxolan-2-yl]-1~{H}-purin-6-one, RNA (5'-R(*CP*UP*GP*CP*UP*GP*GP*CP*UP*AP*AP*GP*GP*CP*AP*UP*GP*AP*AP*AP*GP*U)-3'), RNA (5'-R(P*CP*UP*AP*UP*GP*CP*CP*UP*GP*CP*UP*G)-3')
著者Szostak, J.W, Zhang, W.
登録日2019-09-04
公開日2020-12-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural interpretation of the effects of threo-nucleotides on nonenzymatic template-directed polymerization.
Nucleic Acids Res., 49, 2021
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