6F6Z
| Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate | 分子名称: | (2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), Thymidylate synthase | 著者 | Wilk, P, Jarmula, A, Maj, P, Rode, W. | 登録日 | 2017-12-06 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.127 Å) | 主引用文献 | Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies Int J Mol Sci, 22, 2021
|
|
7OP9
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 2,6-dichloropurine | 分子名称: | 2,6-bis(chloranyl)-7H-purine, IMIDAZOLE, MAGNESIUM ION, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-31 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OOZ
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzyloxo-2-chloropurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzyloxo-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OPA
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthiopurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-31 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
7OOY
| Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthio-2-chloropurine | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | 著者 | Narczyk, M, Stefanic, Z. | 登録日 | 2021-05-28 | 公開日 | 2022-05-04 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
|
|
5MX6
| |
5MX4
| |
5MX8
| |
6F52
| |
6F4W
| |
6F5I
| Crystal structure of H. pylori purine nucleoside phosphorylase | 分子名称: | METHANOL, Purine nucleoside phosphorylase DeoD-type | 著者 | Stefanic, Z. | 登録日 | 2017-12-01 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.298 Å) | 主引用文献 | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
|
|
6F5A
| Crystal structure of H. pylori purine nucleoside phosphorylase | 分子名称: | Purine nucleoside phosphorylase DeoD-type | 著者 | Stefanic, Z. | 登録日 | 2017-12-01 | 公開日 | 2018-02-14 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
|
|
6F4X
| |