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7MVU
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BU of 7mvu by Molmil
Single particle cryo-EM structure of the Chaetomium thermophilum Nup192-Nic96 complex (Nup192 residues 1-1756; Nic96 residues 240-301)
分子名称: Nucleoporin NIC96, Nucleoporin NUP192
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-05-15
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.77 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7MNI
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Crystal structure of the N-terminal domain of NUP88 in complex with NUP98 C-terminal Autoproteolytic Domain
分子名称: Nuclear pore complex protein Nup88, Nuclear pore complex protein Nup98
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNY
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BU of 7mny by Molmil
Crystal Structure of Nup358/RanBP2 Ran-binding domain 3 in complex with Ran-GPPNHP
分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, MAGNESIUM ION, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNU
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BU of 7mnu by Molmil
Crystal Structure of the ZnF7 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MO2
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BU of 7mo2 by Molmil
Crystal Structure of the ZnF2 of Nucleoporin NUP153 in complex with Ran-GDP
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MVY
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BU of 7mvy by Molmil
Single particle cryo-EM structure of the Chaetomium thermophilum Nup188-Nic96 complex (Nup188 residues 1-1858; Nic96 residues 240-301)
分子名称: Nucleoporin NIC96, Nucleoporin NUP188
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-05-15
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7MNM
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BU of 7mnm by Molmil
Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 1-752) T585M mutant in complex with Fab fragment
分子名称: Antibody Fab14 Heavy Chain, Antibody Fab14 Light Chain, E3 SUMO-protein ligase RanBP2
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MO5
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BU of 7mo5 by Molmil
Crystal Structure of the ZnF4 of Nucleoporin NUP153 in complex with Ran-GDP
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MNQ
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BU of 7mnq by Molmil
Crystal Structure of the ZnF2 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MW1
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BU of 7mw1 by Molmil
Crystal structure of the Homo sapiens NUP93-NUP53 complex (NUP93 residues 174-819; NUP53 residues 84-150)
分子名称: Nuclear pore complex protein Nup93, Nucleoporin Nup35
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-05-15
公開日2022-06-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
7MNT
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BU of 7mnt by Molmil
Crystal Structure of the ZnF5 or ZnF6 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP
分子名称: E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MO3
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BU of 7mo3 by Molmil
Crystal Structure of the ZnF3 of Nucleoporin NUP153 in complex with Ran-GDP, resolution 2.05 Angstrom
分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A.
登録日2021-05-01
公開日2022-06-15
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
7MW0
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BU of 7mw0 by Molmil
Crystal structure of Homo sapiens NUP93 solenoid (residues 174-819)
分子名称: 1,2-ETHANEDIOL, Nuclear pore complex protein Nup93
著者Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A.
登録日2021-05-15
公開日2022-06-15
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
5K7K
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BU of 5k7k by Molmil
Design and Optimization of Biaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7: Discovery of Clinical Candidate PF-05089771
分子名称: 4-[4-chloranyl-2-(1~{H}-pyrazol-4-yl)phenoxy]-3-cyano-~{N}-(1,3-thiazol-2-yl)benzenesulfonamide, Cytochrome P450 2C9, PROTOPORPHYRIN IX CONTAINING FE
著者Swain, N, Chrencik, J.
登録日2016-05-26
公開日2017-06-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7.
J. Med. Chem., 60, 2017
7JUM
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BU of 7jum by Molmil
Pfs230 D1 domain in complex with neutralizing antibody LMIV230-01
分子名称: Gametocyte surface protein P230, Neutralizing antibody, LMIV230-01 Single-chain Fv
著者Tolia, N, Tang, W.K.
登録日2020-08-20
公開日2021-03-31
最終更新日2021-04-07
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes.
Nat Commun, 12, 2021
1VSC
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BU of 1vsc by Molmil
VCAM-1
分子名称: VASCULAR CELL ADHESION MOLECULE-1
著者Wang, J, Stehle, T, Osborn, L.
登録日1995-04-27
公開日1996-06-20
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of an N-terminal two-domain fragment of vascular cell adhesion molecule 1 (VCAM-1): a cyclic peptide based on the domain 1 C-D loop can inhibit VCAM-1-alpha 4 integrin interaction.
Proc.Natl.Acad.Sci.USA, 92, 1995
7MQD
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BU of 7mqd by Molmil
Bartonella henselae NrnC complexed with pAGG. D4 symmetry.
分子名称: NanoRNase C, RNA (5'-R(P*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQB
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BU of 7mqb by Molmil
Bartonella henselae NrnC bound to pGG. D4 Symmetry
分子名称: NanoRNase C, RNA (5'-R(P*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQC
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BU of 7mqc by Molmil
Bartonella henselae NrnC bound to pGG. C1 reconstruction.
分子名称: NanoRNase C, RNA (5'-R(P*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.64 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQG
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BU of 7mqg by Molmil
Bartonella henselae NrnC complexed with pAAAGG. C1 reconstruction.
分子名称: NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQI
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BU of 7mqi by Molmil
Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. C1 reconstruction.
分子名称: NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.21 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQH
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BU of 7mqh by Molmil
Bartonella henselae NrnC complexed with pAAAGG in the presence of Ca2+. D4 Symmetry.
分子名称: NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQF
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BU of 7mqf by Molmil
Bartonella henselae NrnC complexed with pAAAGG. D4 symmetry.
分子名称: NanoRNase C, RNA (5'-R(P*AP*AP*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
7MQE
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BU of 7mqe by Molmil
Bartonella henselae NrnC complexed with pAGG. C1 reconstruction.
分子名称: NanoRNase C, RNA (5'-R(P*AP*GP*G)-3')
著者Lormand, J.D, Brownfield, B, Fromme, J.C, Sondermann, H.
登録日2021-05-05
公開日2021-09-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.69 Å)
主引用文献Structural characterization of NrnC identifies unifying features of dinucleotidases.
Elife, 10, 2021
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