2F5Z
| Crystal Structure of Human Dihydrolipoamide Dehydrogenase (E3) Complexed to the E3-Binding Domain of Human E3-Binding Protein | 分子名称: | Dihydrolipoyl dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, Pyruvate dehydrogenase protein X component, ... | 著者 | Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T. | 登録日 | 2005-11-28 | 公開日 | 2006-01-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex. Structure, 14, 2006
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6BGD
| The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound ligand | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glucose/galactose-binding lipoprotein | 著者 | Brautigam, C.A, Norgard, M.V, Deka, R.K. | 登録日 | 2017-10-27 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Crystal structures of MglB-2 (TP0684), a topologically variant d-glucose-binding protein from Treponema pallidum, reveal a ligand-induced conformational change. Protein Sci., 27, 2018
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6BGC
| The crystal structure of the W145A variant of TpMglB-2 (Tp0684) with bound glucose | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Glucose/galactose-binding lipoprotein, ... | 著者 | Brautigam, C.A, Norgard, M.V, Deka, R.K. | 登録日 | 2017-10-27 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.082 Å) | 主引用文献 | Crystal structures of MglB-2 (TP0684), a topologically variant d-glucose-binding protein from Treponema pallidum, reveal a ligand-induced conformational change. Protein Sci., 27, 2018
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2FQX
| PnrA from Treponema pallidum complexed with guanosine | 分子名称: | GUANOSINE, Membrane lipoprotein tmpC | 著者 | Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. | 登録日 | 2006-01-18 | 公開日 | 2006-02-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
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2FQW
| PnrA from Treponema pallidum as purified from E. coli (bound to inosine) | 分子名称: | INOSINE, Membrane lipoprotein tmpC | 著者 | Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. | 登録日 | 2006-01-18 | 公開日 | 2006-02-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
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2FQY
| PnrA from Treponema pallidum complexed with adenosine. | 分子名称: | ADENOSINE, Membrane lipoprotein tmpC | 著者 | Brautigam, C.A, Deka, R.K, Tomchick, D.R, Machius, M, Norgard, M.V. | 登録日 | 2006-01-18 | 公開日 | 2006-02-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum J.Biol.Chem., 281, 2006
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7MGT
| Ftp from Treponema pallidum bound to an ADP-like inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-chloroadenosine 5'-(trihydrogen diphosphate), FAD:protein FMN transferase, ... | 著者 | Brautigam, C.A, Deka, R, Norgard, M.V. | 登録日 | 2021-04-13 | 公開日 | 2021-12-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Inhibition of bacterial FMN transferase: A potential avenue for countering antimicrobial resistance. Protein Sci., 31, 2022
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4DA1
| Crystal structure of branched-chain alpha-ketoacid dehydrogenase phosphatase with Mg (II) ions at the active site | 分子名称: | BETA-MERCAPTOETHANOL, MAGNESIUM ION, Protein phosphatase 1K, ... | 著者 | Brautigam, C.A, Chuang, J.L, Chuang, D.T. | 登録日 | 2012-01-12 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.383 Å) | 主引用文献 | Structural and biochemical characterization of human mitochondrial branched-chain alpha-ketoacid dehydrogenase phosphatase. J.Biol.Chem., 287, 2012
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7JP2
| Crystal structure of TP0037 from Treponema pallidum, a D-lactate dehydrogenase | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, D-lactate dehydrogenase | 著者 | Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2020-08-07 | 公開日 | 2020-09-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | Biophysical and Biochemical Characterization of TP0037, a d-Lactate Dehydrogenase, Supports an Acetogenic Energy Conservation Pathway in Treponema pallidum. Mbio, 11, 2020
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4IIL
| Crystal Structure of RfuA (TP0298) of T. pallidum Bound to Riboflavin | 分子名称: | 1,2-ETHANEDIOL, Membrane lipoprotein TpN38(b), POTASSIUM ION, ... | 著者 | Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2012-12-20 | 公開日 | 2013-02-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Evidence for an ABC-type riboflavin transporter system in pathogenic spirochetes. MBio, 4, 2013
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3SI7
| The crystal structure of the NBD1 domain of the mouse CFTR protein, deltaF508 mutant | 分子名称: | ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | 著者 | Brautigam, C.A, Caspa, E, Thomas, P.J. | 登録日 | 2011-06-17 | 公開日 | 2012-02-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Requirements for efficient correction of DeltaF508 CFTR revealed by analyses of evolved sequences Cell(Cambridge,Mass.), 148, 2012
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3Q6S
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3U65
| The Crystal Structure of Tat-P(T) (Tp0957) | 分子名称: | 1,2-ETHANEDIOL, THIOCYANATE ION, Tp33 protein | 著者 | Brautigam, C.A, Tomchick, D.R, Deka, R.K, Norgard, M.V. | 登録日 | 2011-10-12 | 公開日 | 2012-02-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter. J.Mol.Biol., 416, 2012
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6DET
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1WCI
| Reactivity modulation of human branched-chain alpha-ketoacid dehydrogenase by an internal molecular switch | 分子名称: | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, C2-1-HYDROXY-3-METHYL-BUTYL-THIAMIN, ... | 著者 | Machius, M, Wynn, R.M, Chuang, J.L, Tomchick, D.R, Brautigam, C.A, Chuang, D.T. | 登録日 | 2004-11-16 | 公開日 | 2006-02-16 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure, 14, 2006
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3LET
| Crystal Structure of Fic domain containing AMPylator, VopS | 分子名称: | Adenosine monophosphate-protein transferase vopS | 著者 | Luong, P.H, Kinch, L.N, Brautigam, C.A, Grishin, N.V, Tomchick, D.R, Orth, K. | 登録日 | 2010-01-15 | 公開日 | 2010-04-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Structural and Kinetic Analysis of VopS with Fic Domain Supports a Direct Transfer Mechanism for AMPylation To be Published
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3U64
| The Crystal Structure of Tat-T (Tp0956) | 分子名称: | Protein TP_0956, SULFATE ION | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2011-10-12 | 公開日 | 2012-02-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural, Bioinformatic, and In Vivo Analyses of Two Treponema pallidum Lipoproteins Reveal a Unique TRAP Transporter. J.Mol.Biol., 416, 2012
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4ZJ8
| Structures of the human OX1 orexin receptor bound to selective and dual antagonists | 分子名称: | OLEIC ACID, [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl][5-methyl-2-(2H-1,2,3-triazol-2-yl)phenyl]methanone, human OX1R fusion protein to P.abysii glycogen synthase | 著者 | Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P, Renger, J.J, Rosenbaum, D.M. | 登録日 | 2015-04-29 | 公開日 | 2016-03-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | 主引用文献 | Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. Nat.Struct.Mol.Biol., 23, 2016
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4ZJC
| Structures of the human OX1 orexin receptor bound to selective and dual antagonists | 分子名称: | OLEIC ACID, [5-(2-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]{(2S)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]pyrrolidin-1-yl}methanone, human OX1R fusion protein to P.abysii glycogen synthase | 著者 | Yin, J, Brautigam, C.A, Shao, Z, Clark, L, Harrell, C.M, Gotter, A.L, Coleman, P.J, Renger, J.J, Rosenbaum, D.M. | 登録日 | 2015-04-29 | 公開日 | 2016-03-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.832 Å) | 主引用文献 | Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors. Nat.Struct.Mol.Biol., 23, 2016
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4XHF
| Crystal structure of Shewanella oneidensis NqrC | 分子名称: | FLAVIN MONONUCLEOTIDE, Na-translocating NADH-quinone reductase subunit C NqrC, SODIUM ION | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2015-01-05 | 公開日 | 2015-12-16 | 最終更新日 | 2016-03-16 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
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4XDT
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional FMN transferase/FAD pyrophosphatase, N55Y mutant, FAD bound form | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, FAD:protein FMN transferase, ... | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2014-12-19 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.452 Å) | 主引用文献 | Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein. Mbio, 6, 2015
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4XGV
| Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2015-01-02 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.883 Å) | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
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4XDU
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein,a bifunctional FMN transferase/FAD pyrophosphatase, N55Y mutant, ADP bound form | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2014-12-20 | 公開日 | 2015-10-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein. Mbio, 6, 2015
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4XGX
| Crystal structure of Escherichia coli Flavin trafficking protein, an FMN transferase, Y60N mutant, ADP-inhibited | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FAD:protein FMN transferase, ... | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2015-01-02 | 公開日 | 2015-12-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insights into the enzymatic diversity of flavin-trafficking protein (Ftp; formerly ApbE) in flavoprotein biogenesis in the bacterial periplasm. Microbiologyopen, 5, 2016
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4XDR
| Crystal structure of Treponema pallidum TP0796 Flavin trafficking protein, a bifunctional FMN transferase/FAD pyrophosphatase, D284A mutant, ADN bound form | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ADENOSINE, ... | 著者 | Tomchick, D.R, Brautigam, C.A, Deka, R.K, Norgard, M.V. | 登録日 | 2014-12-19 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Evidence for Posttranslational Protein Flavinylation in the Syphilis Spirochete Treponema pallidum: Structural and Biochemical Insights from the Catalytic Core of a Periplasmic Flavin-Trafficking Protein. Mbio, 6, 2015
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