1PWX
| Crystal structure of the haloalcohol dehalogenase HheC complexed with bromide | 分子名称: | BROMIDE ION, halohydrin dehalogenase | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2003-07-02 | 公開日 | 2003-10-07 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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1NX9
| Acetobacter turbidans alpha-amino acid ester hydrolase S205A mutant complexed with ampicillin | 分子名称: | (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, GLYCEROL, alpha-amino acid ester hydrolase | 著者 | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2003-02-10 | 公開日 | 2004-03-09 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Acetobacter turbidans {alpha}-Amino Acid Ester Hydrolase: HOW A SINGLE MUTATION IMPROVES AN ANTIBIOTIC-PRODUCING ENZYME. J.Biol.Chem., 281, 2006
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3ZN2
| protein engineering of halohydrin dehalogenase | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, ACETATE ION, HALOHYDRIN DEHALOGENASE, ... | 著者 | Schallmey, M, Jekel, P, Tang, L, Majeric-Elenkov, M, Hoeffken, H.W, Hauer, B, Janssen, D.B. | 登録日 | 2013-02-13 | 公開日 | 2014-03-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A Single Point Mutation Enhances Hydroxynitrile Synthesis by Halohydrin Dehalogenase. Enzyme.Microb.Technol., 70, 2015
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4AO4
| Structural Determinants of the beta-Selectivity of a Bacterial Aminotransferase | 分子名称: | (3R)-3-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]-5-METHYLHEXANOIC ACID, 1,2-ETHANEDIOL, Beta-transaminase | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2012-03-23 | 公開日 | 2012-06-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural determinants of the beta-selectivity of a bacterial aminotransferase. J. Biol. Chem., 287, 2012
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1PWZ
| Crystal structure of the haloalcohol dehalogenase HheC complexed with (R)-styrene oxide and chloride | 分子名称: | CHLORIDE ION, R-STYRENE OXIDE, halohydrin dehalogenase | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2003-07-02 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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4AO9
| Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from Variovorax paradoxus | 分子名称: | BETA-PHENYLALANINE AMINOTRANSFERASE, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE | 著者 | Crismaru, C.G, Wybenga, G.G, Szymanski, W, Wijma, H.J, Wu, B, deWildeman, S, Poelarends, G.J, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-03-25 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Biochemical Properties and Crystal Structure of a Novel Beta-Phenylalanine Aminotransferase from Variovorax Paradoxus Appl.Environ.Microbiol., 79, 2013
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4AOA
| Biochemical properties and crystal structure of a novel beta- phenylalanine aminotransferase from Variovorax paradoxus | 分子名称: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, BETA-PHENYLALANINE AMINOTRANSFERASE, GLYCEROL | 著者 | Crismaru, C.G, Wybenga, G.G, Szymanski, W, Wijma, H.J, Wu, B, deWildeman, S, Poelarends, G.J, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-03-25 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Biochemical Properties and Crystal Structure of a Beta-Phenylalanine Aminotransferase from Variovorax Paradoxus. Appl.Environ.Microbiol., 79, 2013
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3ZVH
| Methylaspartate ammonia lyase from Clostridium tetanomorphum mutant Q73A | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Raj, H, Szymanski, W, de Villiers, J, Rozeboom, H.J, Veetil, V.P, Reis, C.R, de Villiers, M, de Wildeman, S, Dekker, F.J, Quax, W.J, Thunnissen, A.M.W.H, Feringa, B.L, Janssen, D.B, Poelarends, G.J. | 登録日 | 2011-07-25 | 公開日 | 2012-05-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Engineering Methylaspartate Ammonia Lyase for the Asymmetric Synthesis of Unnatural Amino Acids. Nat.Chem., 4, 2012
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4BAB
| Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | 分子名称: | PHENYLALANINE AMINOMUTASE | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-09-12 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase To be Published
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4BAA
| Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | 分子名称: | PHENYLALANINE AMMONIA-LYASE | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-09-12 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase To be Published
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3ZVI
| Methylaspartate ammonia lyase from Clostridium tetanomorphum mutant L384A | 分子名称: | CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... | 著者 | Raj, H, Szymanski, W, de Villiers, J, Rozeboom, H.J, Veetil, V.P, Reis, C.R, de Villiers, M, de Wildeman, S, Dekker, F.J, Quax, W.J, Thunnissen, A.M.W.H, Feringa, B.L, Janssen, D.B, Poelarends, G.J. | 登録日 | 2011-07-25 | 公開日 | 2012-05-02 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Engineering Methylaspartate Ammonia Lyase for the Asymmetric Synthesis of Unnatural Amino Acids. Nat.Chem., 4, 2012
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1PX0
| Crystal structure of the haloalcohol dehalogenase HheC complexed with the haloalcohol mimic (R)-1-para-nitro-phenyl-2-azido-ethanol | 分子名称: | (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, halohydrin dehalogenase | 著者 | de Jong, R.M, Tiesinga, J.J.W, Rozeboom, H.J, Kalk, K.H, Tang, L, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2003-07-02 | 公開日 | 2003-10-07 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Mechanism of a Bacterial Haloalcohol Dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site EMBO J., 22, 2003
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2YII
| Manipulating the regioselectivity of phenylalanine aminomutase: new insights into the reaction mechanism of MIO-dependent enzymes from structure-guided directed evolution | 分子名称: | BETA-MERCAPTOETHANOL, FORMIC ACID, GLYCEROL, ... | 著者 | Wu, B, Szymanski, W, Wybenga, G.G, Heberling, M.M, Bartsch, S, Wildeman, S, Poelarends, G.J, Feringa, B.L, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2011-05-13 | 公開日 | 2011-11-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Mechanism-Inspired Engineering of Phenylalanine Aminomutase for Enhanced Beta-Regioselective Asymmetric Amination of Cinnamates. Angew.Chem.Int.Ed.Engl., 51, 2012
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4C5R
| Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis | 分子名称: | (3S)-3-amino-2,2-difluoro-3-phenylpropanoic acid, GLYCEROL, PHENYLALANINE AMMONIA-LYASE | 著者 | Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2013-09-16 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis. Biochemistry, 53, 2014
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4C5S
| Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis | 分子名称: | (3S)-3-amino-2,2-difluoro-3-phenylpropanoic acid, PHENYLALANINE AMMONIA-LYASE | 著者 | Wybenga, G.G, Szymanski, W, Wu, B, Feringa, B.L, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2013-09-16 | 公開日 | 2014-05-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Investigations Into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus Chinensis. Biochemistry, 53, 2014
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2YKV
| Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, BETA-TRANSAMINASE | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2011-05-30 | 公開日 | 2012-05-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase. J.Biol.Chem., 287, 2012
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2YKU
| Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | 分子名称: | 1,2-ETHANEDIOL, BETA-TRANSAMINASE, GLYCEROL, ... | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2011-05-30 | 公開日 | 2012-05-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase. J.Biol.Chem., 287, 2012
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2YKX
| Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | 分子名称: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, BETA-TRANSAMINASE, ... | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2011-05-30 | 公開日 | 2012-05-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase. J.Biol.Chem., 287, 2012
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2YKY
| Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase | 分子名称: | (3S)-3-amino-3-phenylpropanoic acid, 1,2-ETHANEDIOL, BENZENE, ... | 著者 | Wybenga, G.G, Crismaru, C.G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2011-05-30 | 公開日 | 2012-05-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Structural Determinants of the Beta-Selectivity of a Bacterial Aminotransferase. J.Biol.Chem., 287, 2012
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2B4K
| Acetobacter turbidans alpha-amino acid ester hydrolase complexed with phenylglycine | 分子名称: | Alpha-amino acid ester hydrolase, D-PHENYLGLYCINE, GLYCEROL | 著者 | Barends, T.R.M, Polderman-Tijmes, J.J, Jekel, P.A, Williams, C, Wybenga, G, Janssen, D.B, Dijkstra, B.W. | 登録日 | 2005-09-26 | 公開日 | 2005-12-27 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme. J.Biol.Chem., 281, 2006
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6TP2
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6T8F
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6TB0
| Crystal structure of thermostable omega transaminase 4-fold mutant from Pseudomonas jessenii | 分子名称: | Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | 登録日 | 2019-10-31 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Robust omega-Transaminases by Computational Stabilization of the Subunit Interface. Acs Catalysis, 10, 2020
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6T8E
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6TB1
| Crystal structure of thermostable omega transaminase 6-fold mutant from Pseudomonas jessenii | 分子名称: | Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B. | 登録日 | 2019-10-31 | 公開日 | 2020-07-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Robust omega-Transaminases by Computational Stabilization of the Subunit Interface. Acs Catalysis, 10, 2020
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