1E96
| Structure of the Rac/p67phox complex | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, NEUTROPHIL CYTOSOL FACTOR 2 (NCF-2) TPR DOMAIN, ... | 著者 | Lapouge, K, Smith, S.J.M, Walker, P.A, Gamblin, S.J, Smerdon, S.J, Rittinger, K. | 登録日 | 2000-10-10 | 公開日 | 2000-11-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the TPR domain of p67phox in complex with Rac.GTP. Mol.Cell, 6, 2000
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1BGW
| TOPOISOMERASE RESIDUES 410-1202, | 分子名称: | TOPOISOMERASE | 著者 | Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C. | 登録日 | 1996-02-20 | 公開日 | 1996-07-11 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure and mechanism of DNA topoisomerase II. Nature, 379, 1996
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1I49
| CRYSTAL STRUCTURE ANALYSIS OF ARFAPTIN | 分子名称: | ARFAPTIN 2 | 著者 | Tarricone, C, Xiao, B, Justin, N, Gamblin, S.J, Smerdon, S.J. | 登録日 | 2001-02-20 | 公開日 | 2001-05-16 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways. Nature, 411, 2001
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1MXE
| Structure of the Complex of Calmodulin with the Target Sequence of CaMKI | 分子名称: | CALCIUM ION, Calmodulin, Target Sequence of rat Calmodulin-Dependent Protein Kinase I | 著者 | Clapperton, J.A, Martin, S.R, Smerdon, S.J, Gamblin, S.J, Bayley, P.M. | 登録日 | 2002-10-02 | 公開日 | 2002-12-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structure of the Complex
of Calmodulin with the Target
Sequence of Calmodulin-Dependent
Protein Kinase I: Studies of the
Kinase Activation Mechanism Biochemistry, 41, 2002
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1LDN
| STRUCTURE OF A TERNARY COMPLEX OF AN ALLOSTERIC LACTATE DEHYDROGENASE FROM BACILLUS STEAROTHERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Wigley, D.B, Gamblin, S.J, Turkenburg, J.P, Dodson, E.J, Piontek, K, Muirhead, H, Holbrook, J.J. | 登録日 | 1991-11-19 | 公開日 | 1994-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of a ternary complex of an allosteric lactate dehydrogenase from Bacillus stearothermophilus at 2.5 A resolution. J.Mol.Biol., 223, 1992
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5ISO
| STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) | 分子名称: | 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... | 著者 | Xiao, B, Hubbard, J.A, Gamblin, S.J. | 登録日 | 2016-03-15 | 公開日 | 2017-03-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | STRUCTURE OF FULL LENGTH HUMAN AMPK (NON-PHOSPHORYLATED AT T-LOOP) IN COMPLEX WITH A SMALL MOLECULE ACTIVATOR, A BENZIMIDAZOLE DERIVATIVE (991) To Be Published
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5JW5
| Structure of MEDI8852 Fab Fragment | 分子名称: | MEDI8852 Heavy chain, MEDI8852 Light chain, PHOSPHATE ION | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
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5JW3
| Structure of MEDI8852 Fab Fragment in Complex with H7 HA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Collins, P.J, Neu, U, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.75 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
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5JW4
| Structure of MEDI8852 Fab Fragment in Complex with H5 HA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... | 著者 | Neu, U, Collins, P.J, Walker, P.A, Vorlaender, M.K, Ogrodowicz, R.W, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2016-05-11 | 公開日 | 2016-08-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structure and Function Analysis of an Antibody Recognizing All Influenza A Subtypes. Cell, 166, 2016
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3CKZ
| N1 Neuraminidase H274Y + Zanamivir | 分子名称: | CALCIUM ION, Neuraminidase, ZANAMIVIR | 著者 | Colllins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | 登録日 | 2008-03-18 | 公開日 | 2008-05-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453, 2008
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3CL2
| N1 Neuraminidase N294S + Oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | 登録日 | 2008-03-18 | 公開日 | 2008-05-20 | 最終更新日 | 2018-08-22 | 実験手法 | X-RAY DIFFRACTION (2.538 Å) | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453, 2008
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3CL0
| N1 Neuraminidase H274Y + oseltamivir | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase | 著者 | Collins, P, Haire, L.F, Lin, Y.P, Liu, J, Russell, R.J, Walker, P.A, Skehel, J.J, Martin, S.R, Hay, A.J, Gamblin, S.J. | 登録日 | 2008-03-18 | 公開日 | 2008-05-20 | 最終更新日 | 2018-08-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants. Nature, 453, 2008
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3EYM
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.A, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
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3EYJ
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinahuer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
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3EYK
| Structure of Influenza Haemagglutinin in complex with an inhibitor of membrane fusion | 分子名称: | 2-tert-butylbenzene-1,4-diol, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain | 著者 | Russell, R.J, Kerry, P.S, Stevens, D.J, Steinhauer, D.A, Martin, S.R, Gamblin, S.J, Skehel, J.J. | 登録日 | 2008-10-21 | 公開日 | 2009-01-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion Proc.Natl.Acad.Sci.USA, 105, 2008
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3IT5
| Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa | 分子名称: | Protease lasA, ZINC ION | 著者 | Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J. | 登録日 | 2009-08-27 | 公開日 | 2009-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J.Mol.Biol., 396, 2010
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3IIY
| Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide | 分子名称: | Histone H1K26 peptide, Polycomb protein EED | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | 登録日 | 2009-08-03 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
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3IIW
| Crystal structure of Eed in complex with a trimethylated histone H3K27 peptide | 分子名称: | Histone H3 peptide, Polycomb protein EED | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | 登録日 | 2009-08-03 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
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3IJ0
| Crystal structure of Eed in complex with a trimethylated histone H3K9 peptide | 分子名称: | Histone H3K9 peptide, Polycomb protein EED | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | 登録日 | 2009-08-03 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
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3IJC
| Crystal structure of Eed in complex with NDSB-195 | 分子名称: | ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, Polycomb protein EED | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | 登録日 | 2009-08-04 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
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3IJ1
| Crystal structure of Eed in complex with a trimethylated histone H4K20 peptide | 分子名称: | Histone H4K20 peptide, Polycomb protein EED | 著者 | Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. | 登録日 | 2009-08-03 | 公開日 | 2009-09-15 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
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3IT7
| Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa | 分子名称: | GLYCEROL, L(+)-TARTARIC ACID, Protease lasA, ... | 著者 | Spencer, J, Murphy, L.M, Conners, R, Sessions, R.B, Gamblin, S.J. | 登録日 | 2009-08-27 | 公開日 | 2009-11-17 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J.Mol.Biol., 396, 2010
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7R15
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7R1A
| Furin Cleaved Alpha Variant SARS-CoV-2 Spike in complex with 3 ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | 登録日 | 2022-02-02 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
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7R10
| Dissociated S1 domain of Alpha Variant SARS-CoV-2 Spike bound to ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike glycoprotein, ... | 著者 | Benton, D.J, Wrobel, A.G, Gamblin, S.J. | 登録日 | 2022-02-02 | 公開日 | 2022-03-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Evolution of the SARS-CoV-2 spike protein in the human host. Nat Commun, 13, 2022
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