5JOO
 
 | | XFEL structure of influenza A M2 wild type TM domain at low pH in the lipidic cubic phase at room temperature | | 分子名称: | CALCIUM ION, CHLORIDE ION, Matrix protein 2 | | 著者 | Thomaston, J.L, Woldeyes, R.A, Fraser, J.S, DeGrado, W.F. | | 登録日 | 2016-05-02 | | 公開日 | 2017-08-02 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.413 Å) | | 主引用文献 | XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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1YOD
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1Y47
 | | Structural studies of designed alpha-helical hairpins | | 分子名称: | CADMIUM ION, dueferri (DF2) | | 著者 | Lahr, S.J, Engel, D.E, Stayrook, S.E, Maglio, O, North, B, Geremia, S, Lombardi, A, DeGrado, W.F. | | 登録日 | 2004-11-30 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Analysis and design of turns in alpha-helical hairpins
J.Mol.Biol., 346, 2005
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2A3D
 | | SOLUTION STRUCTURE OF A DE NOVO DESIGNED SINGLE CHAIN THREE-HELIX BUNDLE (A3D) | | 分子名称: | PROTEIN (DE NOVO THREE-HELIX BUNDLE) | | 著者 | Walsh, S.T.R, Cheng, H, Bryson, J.W, Roder, H, Degrado, W.F. | | 登録日 | 1999-04-01 | | 公開日 | 1999-05-05 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure and dynamics of a de novo designed three-helix bundle protein.
Proc.Natl.Acad.Sci.USA, 96, 1999
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6US9
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6US8
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1QP6
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2KQT
 | | Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine | | 分子名称: | (3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-amine, M2 protein | | 著者 | Cady, S.D, Schmidt-Rohr, K, Wang, J, Soto, C.S, DeGrado, W.F, Hong, M. | | 登録日 | 2009-11-18 | | 公開日 | 2010-02-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers
Nature, 463, 2010
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3LBW
 | | High resolution crystal structure of transmembrane domain of M2 | | 分子名称: | 4-bromobenzoic acid, DI(HYDROXYETHYL)ETHER, M2 protein, ... | | 著者 | Acharya, R, Polishchuk, A.L, DeGrado, W.F. | | 登録日 | 2010-01-08 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus.
Proc.Natl.Acad.Sci.USA, 107, 2010
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5C02
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5ET3
 | | Crystal Structure of De novo Designed Fullerene organizing peptide | | 分子名称: | (C_{60}-I_{h})[5,6]fullerene, Fullerene Organizing Protein (C60Sol-COP-3) | | 著者 | Kim, K.-H, Kim, Y.H, Acharya, R, Kim, N.H, Paul, J, Grigoryan, G, DeGrado, W.F. | | 登録日 | 2015-11-17 | | 公開日 | 2016-05-04 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.671 Å) | | 主引用文献 | Protein-directed self-assembly of a fullerene crystal.
Nat Commun, 7, 2016
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3S0R
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2MUZ
 | | ssNMR structure of a designed rocker protein | | 分子名称: | designed rocker protein | | 著者 | Wang, T, Joh, N, Wu, Y, DeGrado, W.F, Hong, M. | | 登録日 | 2014-09-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2015-01-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | De novo design of a transmembrane Zn2+-transporting four-helix bundle.
Science, 346, 2014
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1COI
 | | DESIGNED TRIMERIC COILED COIL-VALD | | 分子名称: | COIL-VALD, SULFATE ION | | 著者 | Ogihara, N.L, Weiss, M.S, Degrado, W.F, Eisenberg, D. | | 登録日 | 1996-08-10 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of the designed trimeric coiled coil coil-VaLd: implications for engineering crystals and supramolecular assemblies.
Protein Sci., 6, 1997
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1AL1
 | | CRYSTAL STRUCTURE OF ALPHA1: IMPLICATIONS FOR PROTEIN DESIGN | | 分子名称: | ALPHA HELIX PEPTIDE: ELLKKLLEELKG, SULFATE ION | | 著者 | Hill, C.P, Anderson, D.H, Wesson, L, Degrado, W.F, Eisenberg, D. | | 登録日 | 1990-07-02 | | 公開日 | 1991-10-15 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of alpha 1: implications for protein design.
Science, 249, 1990
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6MJH
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6MQU
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6MQ2
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6MPW
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6O3N
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6NV1
 | | Structure of drug-resistant V27A mutant of the influenza M2 proton channel bound to spiroadamantyl amine inhibitor | | 分子名称: | (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, ... | | 著者 | Thomaston, J.L, Liu, L, DeGrado, W.F. | | 登録日 | 2019-02-04 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray Crystal Structures of the Influenza M2 Proton Channel Drug-Resistant V27A Mutant Bound to a Spiro-Adamantyl Amine Inhibitor Reveal the Mechanism of Adamantane Resistance.
Biochemistry, 59, 2020
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4JFX
 | | Structure of phosphotyrosine (pTyr) scaffold bound to pTyr peptide | | 分子名称: | Fab heavy chain, Fab light chain, Phosphopeptide, ... | | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | | 登録日 | 2013-02-28 | | 公開日 | 2013-09-25 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
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4JFZ
 | | Structure of phosphoserine (pSAb) scaffold bound to pSer peptide | | 分子名称: | Fab heavy chain, Fab light chain, PROPANOIC ACID, ... | | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | | 登録日 | 2013-02-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
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4JG1
 | | Structure of phosphoserine/threonine (pSTAb) scaffold bound to pThr peptide | | 分子名称: | Fab heavy chain, Fab light chain, PROPANOIC ACID, ... | | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | | 登録日 | 2013-02-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
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4JG0
 | | Structure of phosphoserine/threonine (pSTAb) scaffold bound to pSer peptide | | 分子名称: | Fab heavy chain, Fab light chain, PROPANOIC ACID, ... | | 著者 | Koerber, J.T, Thomsen, N.D, Hannigan, B.T, Degrado, W.F, Wells, J.A. | | 登録日 | 2013-02-28 | | 公開日 | 2013-08-28 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Nature-inspired design of motif-specific antibody scaffolds.
Nat.Biotechnol., 31, 2013
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