3ZP7
 
 | | Arg90Cit chorismate mutase of Bacillus subtilis in complex with chorismate and prephenate | | 分子名称: | (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, CHORISMATE MUTASE AROH, PREPHENIC ACID | | 著者 | Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U. | | 登録日 | 2013-02-26 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | | 主引用文献 | Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3ZP4
 | | Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog | | 分子名称: | 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, CHORISMATE MUTASE AROH | | 著者 | Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U. | | 登録日 | 2013-02-26 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3ZOP
 | | Arg90Cit chorismate mutase of Bacillus subtilis at 1.6 A resolution | | 分子名称: | CHORISMATE MUTASE AROH | | 著者 | Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U. | | 登録日 | 2013-02-22 | | 公開日 | 2014-04-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
3K8D
 | | Crystal structure of E. coli lipopolysaccharide specific CMP-KDO synthetase in complex with CTP and 2-deoxy-Kdo | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, 3-deoxy-manno-octulosonate cytidylyltransferase, CYTIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Heyes, D.J, Levy, C.W, Lafite, P, Scrutton, N.S, Leys, D. | | 登録日 | 2009-10-14 | | 公開日 | 2009-11-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure-based mechanism of CMP-2-keto-3-deoxymanno-octulonic acid synthetase: convergent evolution of a sugar-activating enzyme with DNA/RNA polymerases
J.Biol.Chem., 284, 2009
|
|
1ZK3
 | | Triclinic crystal structure of the apo-form of R-specific alcohol dehydrogenase (mutant G37D) from Lactobacillus brevis | | 分子名称: | MAGNESIUM ION, R-specific alcohol dehydrogenase | | 著者 | Schlieben, N.H, Niefind, K, Muller, J, Riebel, B, Hummel, W, Schomburg, D. | | 登録日 | 2005-05-02 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
J.Mol.Biol., 349, 2005
|
|
6LM3
 | | Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope | | 分子名称: | Capsid protein | | 著者 | Sun, Z, Huang, L, Xia, D, Wei, Y, Sun, E, Zhu, H, Bian, H, Wu, H, Feng, L, Wang, J, Liu, C. | | 登録日 | 2019-12-24 | | 公開日 | 2020-02-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Neutralization Mechanism of a Monoclonal Antibody Targeting a Porcine Circovirus Type 2 Cap Protein Conformational Epitope.
J.Virol., 94, 2020
|
|
6EZC
 | | Crystal Structure of human tRNA-dihydrouridine(20) synthase catalytic domain E294K Q305K double mutant | | 分子名称: | CHLORIDE ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ... | | 著者 | Bou-Nader, C, Bregeon, D, Vincent, G, Fontecave, M, Hamdane, D. | | 登録日 | 2017-11-14 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Electrostatic Potential in the tRNA Binding Evolution of Dihydrouridine Synthases.
Biochemistry, 57, 2018
|
|
3ZJF
 | | A20 OTU domain with irreversibly oxidised Cys103 from 270 min H2O2 soak. | | 分子名称: | A20P50, CHLORIDE ION | | 著者 | Kulathu, Y, Garcia, F.J, Mevissen, T.E.T, Busch, M, Arnaudo, N, Carroll, K.S, Barford, D, Komander, D. | | 登録日 | 2013-01-17 | | 公開日 | 2013-03-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation
Nat.Commun., 4, 2013
|
|
5TVY
 | | Computationally Designed Fentanyl Binder - Fen49 | | 分子名称: | 3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL, Endo-1,4-beta-xylanase A | | 著者 | Bick, M.J, Greisen, P.J, Morey, K.J, Antunes, M.S, La, D, Sankaran, B, Reymond, L, Johnsson, K, Medford, J.I, Baker, D. | | 登録日 | 2016-11-10 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Computational design of environmental sensors for the potent opioid fentanyl.
Elife, 6, 2017
|
|
6M9I
 | | L-GSTSTA from degenerate octameric repeats in InaZ, residues 707-712 | | 分子名称: | Ice nucleation protein | | 著者 | Zee, C, Glynn, C, Gallagher-Jones, M, Miao, J, Santiago, C.G, Cascio, D, Gonen, T, Sawaya, M.R, Rodriguez, J.A. | | 登録日 | 2018-08-23 | | 公開日 | 2019-03-27 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.9 Å) | | 主引用文献 | Homochiral and racemic MicroED structures of a peptide repeat from the ice-nucleation protein InaZ.
IUCrJ, 6, 2019
|
|
6SC7
 | | dAb3/HOIP-RBR-Ligand3 | | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase RNF31, SULFATE ION, ... | | 著者 | Tsai, Y.-C.I, Johansson, H, House, D, Rittinger, K. | | 登録日 | 2019-07-23 | | 公開日 | 2019-11-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | | 主引用文献 | Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases.
Cell Chem Biol, 27, 2020
|
|
4QR1
 | |
6SCM
 | | SOS1 in Complex with Inhibitor BI-3406 | | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Son of sevenless homolog 1, ... | | 著者 | Kessler, D, Fischer, G, Ramharter, J. | | 登録日 | 2019-07-24 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.866 Å) | | 主引用文献 | BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition.
Cancer Discov, 11, 2021
|
|
2E8Y
 | | Crystal structure of pullulanase type I from Bacillus subtilis str. 168 | | 分子名称: | ACETATE ION, AmyX protein, CALCIUM ION, ... | | 著者 | Mikami, B, Malle, D, Utsumi, S, Iwamoto, H, Katsuya, Y. | | 登録日 | 2007-01-24 | | 公開日 | 2008-02-19 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Crystal structure of pullulanase type I from Bacillus subtilis str. 168
in complex with maltose and alpha-cyclodextrin
To be Published
|
|
3ZNX
 | | Crystal structure of the OTU domain of OTULIN D336A mutant | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D. | | 登録日 | 2013-02-18 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
|
|
1ZK4
 | | Structure of R-specific alcohol dehydrogenase (wildtype) from Lactobacillus brevis in complex with acetophenone and NADP | | 分子名称: | 1-PHENYLETHANONE, MAGNESIUM ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Schlieben, N.H, Niefind, K, Muller, J, Riebel, B, Hummel, W, Schomburg, D. | | 登録日 | 2005-05-02 | | 公開日 | 2005-06-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
J.Mol.Biol., 349, 2005
|
|
5UBL
 | | A circularly permuted version of PvdQ (cpPvdQ) | | 分子名称: | Acyl-homoserine lactone acylase PvdQ | | 著者 | Wu, R, Mascarenhas, R, Catlin, D, Clevenger, K, Fast, W, Liu, D. | | 登録日 | 2016-12-20 | | 公開日 | 2017-03-01 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Circular Permutation Reveals a Chromophore Precursor Binding Pocket of the Siderophore Tailoring Enzyme PvdQ
To Be Published
|
|
6FFZ
 | | Crystal structure of R. ruber ADH-A, mutant F43H, Y54L | | 分子名称: | Alcohol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | | 著者 | Dobritzsch, D, Maurer, D, Hamnevik, E, Enugala, T.R, Widersten, M. | | 登録日 | 2018-01-09 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Directed Evolution of Alcohol Dehydrogenase for Improved Stereoselective Redox Transformations of 1-Phenylethane-1,2-diol and Its Corresponding Acyloin.
Biochemistry, 57, 2018
|
|
8B3T
 | | Hen Egg White Lysozyme 4s in situ crystallization | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Henkel, A, Galchenkova, M, Yefanov, O, Hakanpaeae, J, Chapman, H.N, Oberthuer, D. | | 登録日 | 2022-09-16 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | JINXED: just in time crystallization for easy structure determination of biological macromolecules.
Iucrj, 10, 2023
|
|
1ZMX
 | | Crystal structure of D. melanogaster deoxyribonucleoside kinase N64D mutant in complex with thymidine | | 分子名称: | Deoxynucleoside kinase, SULFATE ION, THYMIDINE | | 著者 | Welin, M, Skovgaard, T, Knecht, W, Berenstein, D, Munch-Petersen, B, Piskur, J, Eklund, H. | | 登録日 | 2005-05-11 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D.
Febs J., 272, 2005
|
|
8B3U
 | | Hen Egg White Lysozyme 6s in situ crystallization | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Henkel, A, Galchenkova, M, Yefanov, O, Hakanpaeae, J, Chapman, H.N, Oberthuer, D. | | 登録日 | 2022-09-16 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | JINXED: just in time crystallization for easy structure determination of biological macromolecules.
Iucrj, 10, 2023
|
|
8B3V
 | | Hen Egg White Lysozyme 8s in situ crystallization | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Henkel, A, Galchenkova, M, Yefanov, O, Hakanpaeae, J, Chapman, H.N, Oberthuer, D. | | 登録日 | 2022-09-16 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | JINXED: just in time crystallization for easy structure determination of biological macromolecules.
Iucrj, 10, 2023
|
|
7W3C
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED0_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W3H
 | | Structure of USP14-bound human 26S proteasome in substrate-engaged state ED2.1_USP14 | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
7W39
 | | Structure of USP14-bound human 26S proteasome in state EA2.1_UBL | | 分子名称: | 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 6B, ... | | 著者 | Zhang, S, Zou, S, Yin, D, Wu, Z, Mao, Y. | | 登録日 | 2021-11-25 | | 公開日 | 2022-05-04 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.
Nature, 605, 2022
|
|
