5HC8
 
 | | Crystal structure of lavandulyl diphosphate synthase from Lavandula x intermedia in complex with dimethylallyl diphosphate | | 分子名称: | 2-methylbuta-1,3-diene, 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, MAGNESIUM ION, ... | | 著者 | Liu, M.X, Liu, W.D, Gao, J, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | 登録日 | 2016-01-04 | | 公開日 | 2016-03-02 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure and Function of a "Head-to-Middle" Prenyltransferase: Lavandulyl Diphosphate Synthase
Angew.Chem.Int.Ed.Engl., 55, 2016
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5HC6
 | | Crystal structure of lavandulyl diphosphate synthase from Lavandula x intermedia in apo form | | 分子名称: | SULFATE ION, prenyltransference for protein | | 著者 | Liu, M.X, Liu, W.D, Gao, J, Zheng, Y.Y, Chen, C.C, Guo, R.T. | | 登録日 | 2016-01-04 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure and Function of a "Head-to-Middle" Prenyltransferase: Lavandulyl Diphosphate Synthase
Angew.Chem.Int.Ed.Engl., 55, 2016
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1WVL
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6IPG
 | | Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mg-8oxodGMP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*CP*TP*AP*CP*G)-3'), ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPN
 | | Binary Complex of Human DNA Polymerase Mu with MgdGTP | | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPH
 | | Binary Complex of Human DNA Polymerase Mu with MndATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPE
 | | Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mg-8oxodGMP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPK
 | | Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPM
 | | Binary Complex of Human DNA Polymerase Mu with MgdCTP | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPF
 | | Post-catalytic Complex of Human DNA Polymerase Mu with Templating Cytosine and Mn-8oxodGMP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPL
 | | Binary Complex of Human DNA Polymerase Mu with MgdATP | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPD
 | | Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DNA (5'-D(*CP*GP*GP*CP*AP*TP*AP*CP*G)-3'), ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6IPI
 | | Binary Complex of Human DNA Polymerase Mu with MndCTP | | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6J03
 | | Crystal structure of a cyclase mutant in apo form | | 分子名称: | 12-epi-hapalindole U synthase, CALCIUM ION, amino({3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl}amino)methaniminium | | 著者 | Tang, X.K, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2018-12-20 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural insights into the calcium dependence of Stig cyclases.
Rsc Adv, 9, 2019
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6IPJ
 | | Binary Complex of Human DNA Polymerase Mu with MndTTP | | 分子名称: | DNA-directed DNA/RNA polymerase mu,DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Chang, Y.K, Wu, W.J, Tsai, M.D. | | 登録日 | 2018-11-03 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions.
J.Am.Chem.Soc., 141, 2019
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6KA3
 | | Crystal structure of a Thebaine synthase from Papaver somniferum | | 分子名称: | PALMITIC ACID, SULFATE ION, Thebaine synthase 2 | | 著者 | Xue, J, Yu, X.J, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-06-20 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | Structural insights into thebaine synthase 2 catalysis.
Biochem.Biophys.Res.Commun., 529, 2020
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6KA2
 | | Crystal structure of a Thebaine synthase from Papaver somniferum in complex with TBN | | 分子名称: | (4R,7aR,12bS)-7,9-dimethoxy-3-methyl-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline, Thebaine synthase 2 | | 著者 | Xue, J, Yu, X.J, Huang, J.W, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2019-06-20 | | 公開日 | 2020-06-24 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structural insights into thebaine synthase 2 catalysis.
Biochem.Biophys.Res.Commun., 529, 2020
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7D1D
 | | Crystal structure of Bacteroides thetaiotaomicron glutaminyl cyclase bound to 1-benzylimidazole | | 分子名称: | 1-BENZYL-1H-IMIDAZOLE, Glutamine cyclotransferase, ZINC ION | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-14 | | 公開日 | 2021-04-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D2B
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with a Ni ion bound to the active site | | 分子名称: | Glutaminyl-peptide cyclotransferase, NICKEL (II) ION | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-16 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D2I
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with a Fe ion bound to the active site | | 分子名称: | FE (III) ION, Glutaminyl-peptide cyclotransferase, SULFATE ION | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-16 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D23
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with one K ion bound to the active site | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutaminyl-peptide cyclotransferase, POTASSIUM ION | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-15 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D17
 | | Crystal structure of Macrostomum lignano glutaminyl cyclase | | 分子名称: | Glutaminyl-peptide cyclotransferase, ZINC ION | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-14 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1N
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cu ions bound to the active site | | 分子名称: | BICARBONATE ION, COPPER (II) ION, Glutaminyl-peptide cyclotransferase | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-15 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1Y
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with two Co ions bound to the active site | | 分子名称: | COBALT (II) ION, Glutaminyl-peptide cyclotransferase | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-15 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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7D1P
 | | Crystal structure of Ixodes scapularis glutaminyl cyclase with three Cd ions bound to the active site | | 分子名称: | BICARBONATE ION, CADMIUM ION, Glutaminyl-peptide cyclotransferase | | 著者 | Huang, K.-F, Huang, J.-S, Wu, M.-L, Hsieh, W.-L, Wang, A.H.-J. | | 登録日 | 2020-09-15 | | 公開日 | 2021-04-14 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | A Unique Carboxylic-Acid Hydrogen-Bond Network (CAHBN) Confers Glutaminyl Cyclase Activity on M28 Family Enzymes.
J.Mol.Biol., 433, 2021
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