4LKK
| The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with human receptor analog 6'SLNLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, hemagglutinin | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-07-07 | 公開日 | 2013-11-06 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKG
| The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with avian receptor analog 3'SLNLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-07-07 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.994 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LG8
| Crystal structure of PRPF19 WD40 repeats | 分子名称: | Pre-mRNA-processing factor 19, SODIUM ION, UNKNOWN ATOM OR ION | 著者 | Xu, C, Tempel, W, He, H, Dobrovetsky, E, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2013-06-27 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Crystal structure of the WD40 domain of human PRPF19. Biochem. Biophys. Res. Commun., 493, 2017
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4FZX
| Exonuclease X in complex with 3' overhanging duplex DNA | 分子名称: | DNA (5'-D(P*CP*GP*GP*AP*TP*CP*CP*AP*CP*AP*AP*TP*GP*AP*CP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, ... | 著者 | Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T. | 登録日 | 2012-07-08 | 公開日 | 2013-07-03 | 最終更新日 | 2013-10-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease Nucleic Acids Res., 41, 2013
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4Q9V
| Crystal structure of TIPE3 | 分子名称: | CHLORIDE ION, SULFATE ION, Tumor necrosis factor alpha-induced protein 8-like protein 3 | 著者 | Wu, J, Zhang, X, Chen, Y.H, Shi, Y. | 登録日 | 2014-05-02 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer. Cancer Cell, 26, 2014
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7XEY
| EDS1-PAD4 complexed with pRib-ADP | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-O-phosphono-beta-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Huang, S, Jia, A, Xiao, Y. | 登録日 | 2022-03-31 | 公開日 | 2022-07-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity. Science, 377, 2022
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7YE9
| SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-05 | 公開日 | 2022-08-24 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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6V8Y
| Structure of a Sodium Potassium ion Channel | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, POTASSIUM ION, Potassium channel protein, ... | 著者 | Roy, R, Weiss, K.L, Coates, L. | 登録日 | 2019-12-12 | 公開日 | 2021-04-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Structural plasticity of the selectivity filter in a nonselective ion channel. Iucrj, 8, 2021
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7YC9
| Co-crystal structure of BTK kinase domain with inhibitor | 分子名称: | (7~{S})-2-(4-bromanyl-3,5-dimethoxy-phenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, 1,2-ETHANEDIOL, Tyrosine-protein kinase BTK | 著者 | Zhou, X. | 登録日 | 2022-07-01 | 公開日 | 2023-05-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases. J.Med.Chem., 66, 2023
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6LRI
| Human cGAS catalytic domain bound with compound 17 | 分子名称: | 3-[5-(2-hydroxy-2-oxoethyl)-3-oxidanylidene-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
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6LRE
| Human cGAS catalytic domain bound with compound 3 | 分子名称: | 1,3-bis(oxidanylidene)benzo[de]isoquinoline-6,7-dicarboxylic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
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6LRK
| Human cGAS catalytic domain bound with compound 40 | 分子名称: | (3R)-1-pyrrolo[1,2-a]quinoxalin-4-ylpiperidine-3-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
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7YDY
| SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-04 | 公開日 | 2022-08-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.75 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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7YEG
| SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-05 | 公開日 | 2022-08-24 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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7YDI
| SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-04 | 公開日 | 2022-08-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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6UZK
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7YE5
| SARS-CoV-2 Spike (6P) in complex with 2 R1-32 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-05 | 公開日 | 2022-08-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (6.75 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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6LRJ
| Human cGAS catalytic domain bound with compound 23 | 分子名称: | 4-[2-(2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl)hydrazinyl]-4-oxidanylidene-butanoic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
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6LRL
| Human cGAS catalytic domain bound with compound s2 | 分子名称: | 3-[[5-(1,2,4-triazol-4-yl)-4H-1,2,4-triazol-3-yl]carbonylamino]benzoic acid, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. | 登録日 | 2020-01-16 | 公開日 | 2020-06-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.655 Å) | 主引用文献 | In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
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6W9H
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6W9I
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3SF5
| Crystal Structure of Helicobacter pylori Urease Accessory Protein UreF/H complex | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... | 著者 | Fong, Y.H, Chen, Y.W, Wong, K.B. | 登録日 | 2011-06-12 | 公開日 | 2011-11-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | 主引用文献 | Assembly of preactivation complex for urease maturation in Helicobacter pylori: crystal structure of UreF-UreH protein complex J.Biol.Chem., 286, 2011
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5XXE
| Crystal structure of Poz1 and Tpz1 | 分子名称: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, SULFATE ION, ... | 著者 | Xue, J, Chen, H, Wu, J, Lei, M. | 登録日 | 2017-07-03 | 公開日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Res., 27, 2017
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5GM5
| Crystal structure of FI-CMCase from Aspergillus aculeatus F-50 in complex with cellobiose | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endoglucanase-1, SULFATE ION, ... | 著者 | Huang, J.W, Liu, W.D, Zheng, Y.Y, Chen, C.C, Guo, R.T. | 登録日 | 2016-07-12 | 公開日 | 2017-05-17 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50 Biochem. Biophys. Res. Commun., 478, 2016
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5XXF
| Crystal structure of Poz1, Tpz1 and Rap1 | 分子名称: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, Rap1, ... | 著者 | Xue, J, Chen, H, Wu, J, Lei, M. | 登録日 | 2017-07-03 | 公開日 | 2017-12-20 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Res., 27, 2017
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