5K7O
| MicroED structure of lysozyme at 1.8 A resolution | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
5K7T
| MicroED structure of thermolysin at 2.5 A resolution | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ... | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
5K7N
| MicroED structure of tau VQIVYK peptide at 1.1 A resolution | 分子名称: | VQIVYK | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.1 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
5K7S
| MicroED structure of proteinase K at 1.6 A resolution | 分子名称: | CALCIUM ION, Proteinase K | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2018-08-22 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.6 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
5KO0
| Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED | 分子名称: | THIOCYANATE ION, hIAPP(15-25)WT | 著者 | Krotee, P.A.L, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Shi, D, Nannenga, B.L, Hattne, J, Reyes, F.E, Gonen, T, Eisenberg, D.S. | 登録日 | 2016-06-28 | 公開日 | 2016-12-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | 主引用文献 | Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important for cytotoxicity. Elife, 6, 2017
|
|
5K7P
| MicroED structure of xylanase at 2.3 A resolution | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | 登録日 | 2016-05-26 | 公開日 | 2017-04-05 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED. Nat. Methods, 14, 2017
|
|
8T0B
| |
8T1N
| Micro-ED Structure of a Novel Domain of Unknown Function Solved with AlphaFold | 分子名称: | DUF1842 domain-containing protein | 著者 | Miller, J.E, Cascio, D, Sawaya, M.R, Cannon, K.A, Rodriguez, J.A, Yeates, T.O. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-10 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3 Å) | 主引用文献 | AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta Crystallogr D Struct Biol, 80, 2024
|
|
8T1M
| Novel Domain of Unknown Function Solved with AlphaFold | 分子名称: | DUF1842 domain-containing protein | 著者 | Miller, J.E, Agdanowski, M.P, Cascio, D, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-06-02 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | AlphaFold-assisted structure determination of a bacterial protein of unknown function using X-ray and electron crystallography. Acta Crystallogr D Struct Biol, 80, 2024
|
|
8SPA
| Structural insights into cellular control of the human CPEB3 prion, functionally regulated by a labile-amyloid-forming segment | 分子名称: | Cytoplasmic polyadenylation element-binding protein 3 | 著者 | Flores, M.D, Sawaya, M.R, Boyer, D.R, Zink, S, Fioriti, L, Rodriguez, J.A. | 登録日 | 2023-05-02 | 公開日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of a reversible amyloid fibril formed by the CPEB3 prion-like domain reveals a core sequence involved in translational regulation To Be Published
|
|
8TEQ
| Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) G269V mutant, amyloid fiber | 分子名称: | TRK-fused gene protein Low Complexity Domain G269V mutant | 著者 | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | 登録日 | 2023-07-06 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. Pnas Nexus, 2, 2023
|
|
8TER
| Tropomyosin-receptor kinase fused gene protein (TRK-fused gene protein; TFG) Low Complexity Domain (residues 237-327) P285L mutant, amyloid fiber | 分子名称: | TRK-fused gene protein Low Complexity Domain P285L mutant | 著者 | Rosenberg, G.M, Sawaya, M.R, Boyer, D.R, Ge, P, Abskharon, R, Eisenberg, D.S. | 登録日 | 2023-07-06 | 公開日 | 2023-12-20 | 最終更新日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Fibril structures of TFG protein mutants validate the identification of TFG as a disease-related amyloid protein by the IMPAcT method. Pnas Nexus, 2, 2023
|
|
8UMP
| T33-ml35 - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml35-redesigned-CutA-fold, T33-ml35-redesigned-TPR-domain-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-18 | 公開日 | 2023-11-15 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8UF0
| T33-ml23 - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml23-redesigned-CutA-fold, T33-ml23-redesigned-tandem-BMC-T-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-03 | 公開日 | 2023-11-15 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.02 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8UI2
| T33-ml28 - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml28-redesigned-CutA-fold, T33-ml28-redesigned-tandem-BMC-T-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-09 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8UKM
| T33-ml30 - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml30-redesigned-4-OT-fold, T33-ml30-redesigned-tandem-BMC-T-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-14 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8UN1
| T33-ml23 Assembly Intermediate - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml23-redesigned-CutA-fold, T33-ml23-redesigned-tandem-BMC-T-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-18 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8UMR
| T33-ml35 Assembly Intermediate - Designed Tetrahedral Protein Cage Using Machine Learning Algorithms | 分子名称: | T33-ml35-redesigned-CutA-fold, T33-ml35-redesigned-TPR-domain-fold | 著者 | Castells-Graells, R, Meador, K, Sawaya, M.R, Yeates, T.O. | 登録日 | 2023-10-18 | 公開日 | 2024-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | 主引用文献 | A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure, 32, 2024
|
|
8V9O
| Imaging scaffold engineered to bind the therapeutic protein target BARD1 | 分子名称: | CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... | 著者 | Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. | 登録日 | 2023-12-08 | 公開日 | 2024-05-15 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (3.81 Å) | 主引用文献 | X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr.,Sect.F, 80, 2024
|
|
6UFA
| S4 symmetric peptide design number 1, Tim zinc-bound form | 分子名称: | S4-1, Tim, Zinc-bound form, ... | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-24 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (0.77 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
6UG2
| C2 symmetric peptide design number 1, Zappy, crystal form 2 | 分子名称: | C2-1, Zappy, crystal form 2, ... | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-25 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
6UF4
| S2 symmetric peptide design number 4 crystal form 2, Pugsley | 分子名称: | S2-4, Pusgley crystal form 2 | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-23 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
6UF9
| S4 symmetric peptide design number 1, Tim apo form | 分子名称: | S4-1, Tim apo-form, SULFATE ION | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-24 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
6UG6
| C3 symmetric peptide design number 1, Sporty, crystal form 2 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, C3-1, ... | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-25 | 公開日 | 2020-12-02 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|
6UDW
| S2 symmetric peptide design number 3 crystal form 2, Lurch | 分子名称: | S2-3, Lurch crystal form 2 | 著者 | Mulligan, V.K, Kang, C.S, Antselovich, I, Sawaya, M.R, Yeates, T.O, Baker, D. | 登録日 | 2019-09-19 | 公開日 | 2020-09-23 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Computational design of mixed chirality peptide macrocycles with internal symmetry. Protein Sci., 29, 2020
|
|