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7K79
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CBF3
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, Suppressor of kinetochore protein 1
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
7K7G
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BU of 7k7g by Molmil
nucleosome and Gal4 complex
分子名称: Centromere DNA-binding protein complex CBF3 subunit B, DNA (147-MER), Histone H2A.1, ...
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
7K78
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antibody and nucleosome complex
分子名称: Cse4, DNA (136-MER), Histone H2A.1, ...
著者Ruifang, G, Yawen, B.
登録日2020-09-22
公開日2021-03-31
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and dynamic mechanisms of CBF3-guided centromeric nucleosome formation.
Nat Commun, 12, 2021
7D2T
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BU of 7d2t by Molmil
Crystal structure of Rsu1/PINCH1_LIM45C complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ...
著者Yang, H, Wei, Z, Yu, C.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7VAH
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BU of 7vah by Molmil
The crystal structure of COVID-19 main protease in H41A mutation
分子名称: 3C-like proteinase
著者Liu, X, Zhao, Y, Yang, H, Rao, Z.
登録日2021-08-29
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.491 Å)
主引用文献Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 119, 2022
3HDN
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BU of 3hdn by Molmil
Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2
分子名称: Serine/threonine-protein kinase Sgk1, [4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid
著者Zhao, B, Hammond, M.
登録日2009-05-07
公開日2009-06-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
7D2S
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Crystal structure of Rsu1/PINCH1_LIM5C complex
分子名称: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ...
著者Yang, H, Wei, Z, Cong, Y.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7D2U
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Crystal structure of Rsu1/PINCH1_LIM45C complex
分子名称: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ...
著者Yang, H, Wei, Z, Cong, Y.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7F83
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Crystal Structure of a receptor in Complex with inverse agonist
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone, Growth hormone secretagogue receptor type 1,Soluble cytochrome b562
著者Xu, Z, Shao, Z.
登録日2021-07-01
公開日2022-01-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Molecular mechanism of agonism and inverse agonism in ghrelin receptor.
Nat Commun, 13, 2022
3HDM
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BU of 3hdm by Molmil
Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 1
分子名称: 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid, Serine/threonine-protein kinase Sgk1
著者Zhao, B, Hammond, M.
登録日2009-05-07
公開日2009-06-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
1D4T
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BU of 1d4t by Molmil
CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH A SLAM PEPTIDE
分子名称: SIGNALING LYMPHOCYTIC ACTIVATION MOLECULE, T CELL SIGNAL TRANSDUCTION MOLECULE SAP
著者Poy, F, Yaffe, M.B, Sayos, J, Saxena, K, Eck, M.J.
登録日1999-10-06
公開日1999-10-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.
Mol.Cell, 4, 1999
5GXJ
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BU of 5gxj by Molmil
Zika Virus NS2B-NS3 protease
分子名称: FLAVIVIRUS_NS2B,LINKER,Peptidase S7
著者Yang, H, Chen, X, Ji, X, Xiong, Y, Yang, K.
登録日2016-09-18
公開日2017-05-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Viral protease activation mechanism
To Be Published
7W2Z
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BU of 7w2z by Molmil
Cryo-EM structure of the ghrelin-bound human ghrelin receptor-Go complex
分子名称: Appetite-regulating hormone, CHOLESTEROL, Growth hormone secretagogue receptor type 1, ...
著者Qin, J, Ming, Q, Ji, S, Mao, C, Shen, D, Zhang, Y.
登録日2021-11-24
公開日2022-01-19
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular mechanism of agonism and inverse agonism in ghrelin receptor.
Nat Commun, 13, 2022
5V8C
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BU of 5v8c by Molmil
LytR-Csp2A-Psr enzyme from Actinomyces oris
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, COBALT (II) ION, PHOSPHATE ION, ...
著者Amer, B.R, Sawaya, M.R, Liauw, B, Fu, J.Y, Ton-That, H, Clubb, R.T.
登録日2017-03-21
公開日2018-04-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure and Mechanism of LcpA, a Phosphotransferase That Mediates Glycosylation of a Gram-Positive Bacterial Cell Wall-Anchored Protein.
MBio, 10, 2019
5VAO
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BU of 5vao by Molmil
Crystal structure of eVP30 C-terminus and eNP peptide
分子名称: CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者XU, W, Leung, D.W, Amarasinghe, G.K.
登録日2017-03-27
公開日2017-06-21
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis.
Nat Commun, 8, 2017
1D1Z
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BU of 1d1z by Molmil
CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP
分子名称: SAP SH2 DOMAIN, SULFATE ION
著者Poy, F, Yaffe, M.B, Sayos, J, Saxena, K, Eck, M.J.
登録日1999-09-22
公開日1999-10-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition.
Mol.Cell, 4, 1999
8GVK
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BU of 8gvk by Molmil
Cryo-EM structure of streptavidin
分子名称: Streptavidin
著者Liu, N, Zheng, L.M, Peng, H.L, Wang, H.W.
登録日2022-09-15
公開日2022-11-09
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Uniform thin ice on ultraflat graphene for high-resolution cryo-EM.
Nat.Methods, 20, 2023
8GZZ
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BU of 8gzz by Molmil
Local refinement of SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab
分子名称: Spike protein S1, rabbit monoclonal antibody 1H1 Fab heavy chain, rabbit monoclonal antibody 1H1 Fab light chain
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-09-27
公開日2023-04-12
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants.
Commun Biol, 6, 2023
8H01
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SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in class 2 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-09-27
公開日2023-04-12
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants.
Commun Biol, 6, 2023
8H00
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SARS-CoV-2 Omicron BA.1 Spike glycoprotein in complex with rabbit monoclonal antibody 1H1 Fab in the class 1 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-09-27
公開日2023-04-12
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Mechanism of a rabbit monoclonal antibody broadly neutralizing SARS-CoV-2 variants.
Commun Biol, 6, 2023
8HEC
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SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 2 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-11-08
公開日2023-04-26
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism of an RBM-targeted rabbit monoclonal antibody 9H1 neutralizing SARS-CoV-2.
Biochem.Biophys.Res.Commun., 660, 2023
8HEB
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SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab in the class 1 conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-11-08
公開日2023-04-26
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献Mechanism of an RBM-targeted rabbit monoclonal antibody 9H1 neutralizing SARS-CoV-2.
Biochem.Biophys.Res.Commun., 660, 2023
8HED
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BU of 8hed by Molmil
Local refinement of the SARS-CoV-2 Spike trimer in complex with RmAb 9H1 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Guo, H, Gao, Y, Lu, Y, Yang, H, Ji, X.
登録日2022-11-08
公開日2023-04-26
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Mechanism of an RBM-targeted rabbit monoclonal antibody 9H1 neutralizing SARS-CoV-2.
Biochem.Biophys.Res.Commun., 660, 2023
8H0F
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Crystal structure of collagen heterotrimer with KD,ER and KE axial pairs
分子名称: collagen-like peptide chain A, collagen-like peptide chain B, collagen-like peptide chain C
著者Fan, S.
登録日2022-09-28
公開日2023-07-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Stability of collagen heterotrimer with same charge pattern and different charged residue identities.
Biophys.J., 122, 2023
8GZO
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Crystal structure of collagen heterotrimer with K, D, E, R residuesC
分子名称: collagen-like peptide
著者Fan, S.
登録日2022-09-27
公開日2023-07-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.23 Å)
主引用文献Stability of collagen heterotrimer with same charge pattern and different charged residue identities.
Biophys.J., 122, 2023

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