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1EH6
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BU of 1eh6 by Molmil
HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
分子名称: O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE, ZINC ION
著者Daniels, D.S, Tainer, J.A.
登録日2000-02-18
公開日2000-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding.
EMBO J., 19, 2000
9NSE
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BU of 9nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, ETHYL-ISOSELENOUREA COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, CACODYLIC ACID, ...
著者Li, H, Raman, C.S, Martasek, P, Kral, V, Masters, B.S.S, Poulos, T.L.
登録日1999-01-13
公開日2000-10-25
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Mapping the active site polarity in structures of endothelial nitric oxide synthase heme domain complexed with isothioureas.
J.Inorg.Biochem., 81, 2000
8NSE
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BU of 8nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, NNA COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, CACODYLIC ACID, GLYCEROL, ...
著者Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L.
登録日1999-01-14
公開日2001-11-21
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
Biochemistry, 40, 2001
5CWH
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BU of 5cwh by Molmil
Crystal structure of de novo designed helical repeat protein DHR14
分子名称: 1,2-ETHANEDIOL, Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWO
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BU of 5cwo by Molmil
Crystal structure of de novo designed helical repeat protein DHR76
分子名称: Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWC
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BU of 5cwc by Molmil
Crystal structure of de novo designed helical repeat protein DHR5
分子名称: 1,2-ETHANEDIOL, Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-27
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWM
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BU of 5cwm by Molmil
Crystal structure of de novo designed helical repeat protein DHR64
分子名称: Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWN
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BU of 5cwn by Molmil
Crystal structure of de novo designed helical repeat protein DHR71
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Designed helical repeat protein, TETRAETHYLENE GLYCOL
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWG
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BU of 5cwg by Molmil
Crystal structure of de novo designed helical repeat protein DHR10
分子名称: 1,2-ETHANEDIOL, Designed helical repeat protein, UNKNOWN LIGAND
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWB
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BU of 5cwb by Molmil
Crystal structure of de novo designed helical repeat protein DHR4
分子名称: Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-27
公開日2015-12-16
最終更新日2016-01-06
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWK
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BU of 5cwk by Molmil
Crystal structure of de novo designed helical repeat protein DHR53
分子名称: Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
3E65
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BU of 3e65 by Molmil
Murine INOS dimer with HEME, pterin and inhibitor AR-C120011
分子名称: 1-[4-(AMINOMETHYL)BENZOYL]-5'-FLUORO-1'H-SPIRO[PIPERIDINE-4,2'-QUINAZOLIN]-4'-AMINE, 5,6,7,8-TETRAHYDROBIOPTERIN, Nitric oxide synthase, ...
著者Rosenfeld, R.J, Garcin, E.D, Getzoff, E.D.
登録日2008-08-14
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
4WHV
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BU of 4whv by Molmil
E3 ubiquitin-protein ligase RNF8 in complex with Ubiquitin-conjugating enzyme E2 N and Polyubiquitin-B
分子名称: E3 ubiquitin-protein ligase RNF8, Polyubiquitin-B, Ubiquitin-conjugating enzyme E2 N, ...
著者Hodge, C.D, Edwards, R.A, Glover, J.N.M.
登録日2014-09-23
公開日2015-09-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (8.3 Å)
主引用文献RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
J.Biol.Chem., 291, 2016
5NSE
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BU of 5nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, HYDROXY-ARG COMPLEX
分子名称: ACETATE ION, CACODYLIC ACID, GLYCEROL, ...
著者Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L.
登録日1999-01-13
公開日2002-05-29
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of the Heme Domain of Bovine Endothelial Nitric Oxide Synthase Complexed with Arginine Analogues
To be Published
6DCX
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BU of 6dcx by Molmil
iASPP-PP-1c structure and targeting of p53
分子名称: RelA-associated inhibitor, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
著者Glover, J.N.M, Zhou, Y, Edwards, R.A.
登録日2018-05-08
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.408 Å)
主引用文献Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
Structure, 27, 2019
3EHW
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BU of 3ehw by Molmil
Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, dUTP pyrophosphatase
著者Takacs, E, Barabas, O, Vertessy, B.G.
登録日2008-09-15
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
To be Published
5IKN
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BU of 5ikn by Molmil
Crystal Structure of the T7 Replisome in the Absence of DNA
分子名称: DNA primase/helicase, DNA-directed DNA polymerase, Thioredoxin-1
著者Wallen, J.R, Ellenberger, T.
登録日2016-03-03
公開日2016-12-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (4.802 Å)
主引用文献Hybrid Methods Reveal Multiple Flexibly Linked DNA Polymerases within the Bacteriophage T7 Replisome.
Structure, 25, 2017
5JIG
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BU of 5jig by Molmil
Crytsal structure of Wss1 from S. pombe
分子名称: NICKEL (II) ION, OXYGEN MOLECULE, Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c
著者Groll, M, Stingele, J, Boulton, S.
登録日2016-04-22
公開日2016-11-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
Mol.Cell, 64, 2016
2WTE
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BU of 2wte by Molmil
The structure of the CRISPR-associated protein, Csa3, from Sulfolobus solfataricus at 1.8 angstrom resolution.
分子名称: CSA3, DI(HYDROXYETHYL)ETHER
著者Lintner, N.G, Alsbury, D.L, Copie, V, Young, M.J, Lawrence, C.M.
登録日2009-09-15
公開日2010-09-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Structure of the Crispr-Associated Protein Csa3 Provides Insight Into the Regulation of the Crispr/Cas System.
J.Mol.Biol., 405, 2011
5LN5
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BU of 5ln5 by Molmil
Crystal structure of the Wss1 E203Q mutant from S. pombe
分子名称: CARBONATE ION, NICKEL (II) ION, Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c
著者Groll, M, Stingele, J, Boulton, S.J.
登録日2016-08-03
公開日2016-11-09
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN.
Mol.Cell, 64, 2016
4KC3
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BU of 4kc3 by Molmil
Cytokine/receptor binary complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-1 receptor-like 1, Interleukin-33
著者Liu, X, Wang, X.Q.
登録日2013-04-24
公開日2013-08-28
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.2702 Å)
主引用文献Structural insights into the interaction of IL-33 with its receptors.
Proc.Natl.Acad.Sci.USA, 110, 2013
6NSE
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BU of 6nse by Molmil
BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, CANAVANINE COMPLEX
分子名称: ACETATE ION, CACODYLIC ACID, GLYCEROL, ...
著者Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L.
登録日1999-01-13
公開日2002-05-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of the Heme Domain of Bovine Endothelial Nitric Oxide Synthase Complexed with Arginine Analogues
To be Published
5CWD
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BU of 5cwd by Molmil
Crystal structure of de novo designed helical repeat protein DHR7
分子名称: Designed helical repeat protein
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
5CWI
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BU of 5cwi by Molmil
Crystal structure of de novo designed helical repeat protein DHR18
分子名称: Designed helical repeat protein, PHOSPHATE ION
著者Bhabha, G, Ekiert, D.C.
登録日2015-07-28
公開日2015-12-16
最終更新日2016-01-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Exploring the repeat protein universe through computational protein design.
Nature, 528, 2015
2NSI
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BU of 2nsi by Molmil
HUMAN INDUCIBLE NITRIC OXIDE SYNTHASE, ZN-FREE, SEITU COMPLEX
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYLISOTHIOUREA, PROTEIN (NITRIC OXIDE SYNTHASE), ...
著者Li, H, Raman, C.S, Glaser, C.B, Blasko, E, Young, T.A, Parkinson, J.F, Whitlow, M, Poulos, T.L.
登録日1999-01-11
公開日2000-01-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase.
J.Biol.Chem., 274, 1999

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